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First clinical trial launched to test psilocybin therapy for depression in cancer patients

The first clinical trial to test the safety and feasibility of psilocybin therapy with simultaneous administration and one-on-one patient support to treat depression in cancer patients was launched today by Maryland Oncology Hematology at the Aquilino Cancer Center at Adventist HealthCare Shady Grove Medical Center.

16 Sep 2020

Candidate monoclonal antibody shows hope as COVID-19 treatment

Researchers in the United States have described the effectiveness of a candidate monoclonal antibody currently being evaluated in a Phase 1 trial as a therapy for coronavirus disease 2019 (COVID-19) and its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Sep 2020

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a new pill which uses the stomach as a drug reservoir and delivers medicines slowly over time to patients with Parkinson's disease (PD).

16 Sep 2020

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Participation in clinical trials among Black people is low, according to Food and Drug Administration statistics.

16 Sep 2020

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Now, a new study by researchers from Pfizer, University of Arizona, Purdue University, The Scripps Research Institute, and UC San Diego School of Medicine and published on the preprint server bioRxiv in September 2020 reports that an enzyme inhibitor may act in synergism with the approved antiviral remdesivir to suppress viral replication in COVID-19.

16 Sep 2020

Sex and gender not receiving enough attention in COVID-19 trials

Researchers in Denmark and the Netherlands have conducted a study showing that sex and gender are not being adequately considered in clinical trials investigating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) pandemic.

15 Sep 2020

Oxford University and AstraZeneca resume COVID-19 vaccine trial

More than a hundred candidate vaccine trials against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), are underway. About 35 are now undergoing clinical evaluation, and of these, nine are in the final phase of human trials, including the vaccine developed by Oxford University and the biopharmaceutical firm, AstraZeneca.

14 Sep 2020

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

Following a large-scale clinical trial, researchers have found that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease.

14 Sep 2020

International trial of blood thinners for COVID-19 treatment begins

These trials, known as ACTIV-4 Antithrombotics, are part of the three planned adaptive trials in this area of clinical research, included in the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative. They are expected to yield new data on the safety and efficacy of these drugs in the treatment of active and convalescent COVID-19 treatment.

13 Sep 2020

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

Researchers in India have conducted a preclinical study demonstrating the safety and efficacy of a new candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

13 Sep 2020

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers in the United States and Germany have conducted a study demonstrating the preclinical efficacy of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

9 Sep 2020

Study: Generic cholesterol medications save billions of dollars for Medicare

The switch from brand name to generic cholesterol medications that occurred between 2014 and 2018 has saved Medicare billions of dollars, even as the number of people on cholesterol-lowering drugs has increased, UT Southwestern scientists have calculated.

9 Sep 2020

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

The coronavirus disease (COVID-19) pandemic is rippling across the globe, with over 27.47 million reported cases. With the vast spread of the virus, scientists are racing to gain the approval of candidate vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease and Multisystem Inflammatory Syndrome in Children (MIS-C).

8 Sep 2020

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice and performs much better than a conventional mRNA vaccine. This could allow single-dose immunization, allowing progress towards global vaccination.

6 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

Octapharma has launched a phase 3, multi-center superiority study to compare the effectiveness of PANZYGA (immune globulin intravenous, human - ifas) 10% Liquid Preparation versus placebo in patients with pediatric acute-onset neuropsychiatric syndrome (PANS).

3 Sep 2020

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

3 Sep 2020

Corticosteroids can be lifesaving for critically ill COVID-19 patients

Now, a prospective meta-analysis of 7 randomized trials published in the journal JAMA showed that the widely available steroid drugs could help seriously ill patients survive COVID-19.

3 Sep 2020

Experimental drug for ALS shows promising results in clinical trial

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and Amylyx Pharmaceuticals, Inc., the company that manufactures the medication.

2 Sep 2020

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

Vanderbilt University Medical Center is launching a clinical trial of promising treatments for COVID-19 in the outpatient setting.

2 Sep 2020

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Drug Trial News

First clinical trial launched to test psilocybin therapy for depression in cancer patients

Candidate monoclonal antibody shows hope as COVID-19 treatment

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Sex and gender not receiving enough attention in COVID-19 trials

Oxford University and AstraZeneca resume COVID-19 vaccine trial

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

International trial of blood thinners for COVID-19 treatment begins

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Study: Generic cholesterol medications save billions of dollars for Medicare

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

Corticosteroids can be lifesaving for critically ill COVID-19 patients

Experimental drug for ALS shows promising results in clinical trial

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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