Genomics

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The first clinical trials of CRISPR gene editing have shown promising results

Results of clinical trials testing CRISPR suggest that treating diseases with the gene-editing tool may be on the horizon.

7 Jan 2020

Some genetic sequencing misses out large parts of the genome

A study of patient samples has found that more than a quarter of genes are missed in genetic sequencing procedures.

7 Jan 2020

Using CRISPR to switch off pain gene becomes a possibility with new study

A pathbreaking study reports success in disabling an important gene that is responsible for inducing the sensation of pain.

7 Jan 2020

Study uncovers genes controlling mycorrhizal colonization in soybean

Like most plants, soybeans pair up with soil fungi in a symbiotic mycorrhizal relationship. In exchange for a bit of sugar, the fungus acts as an extension of the root system to pull in more phosphorus, nitrogen, micronutrients, and water than the plant could on its own.

6 Jan 2020

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical Center.

6 Jan 2020

Prison sentences given to scientists who gene-edited babies

The three scientists responsible for the creation of three gene-edited babies have received prison sentences.

6 Jan 2020

Competition between groups has negative effects on wild chimpanzees' reproductive success

Both species, humans and chimpanzees, can be extremely territorial, and territorial disputes between groups can turn violent, with individuals killing each other. In humans, such between-group competition can escalate to war and devastating loss of human life.

3 Jan 2020

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Promega announce license agreement with MilliporeSigma, a leader in genome editing, to access MilliporeSigma’s foundational CRISPR genome-editing technology.

From Promega Corporation 2 Jan 2020

Common plasticizer leads to fertility problems in roundworms

A new study published 9th January in PLOS Genetics by Mónica Colaiácovo of Harvard Medical School and colleagues reports that the most commonly used plasticizer, diethylhexyl phthalate, leads to fertility problems by causing an excess number of breaks in the DNA during egg production, and then interfering with the repair systems that fixes the breaks.

2 Jan 2020

Advancement in reconstitution of the blood system from human pluripotent stem cells

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others.

31 Dec 2019

Scientists identify molecules capable of inhibiting DNA methylation, effectively killing malaria parasites

Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes.

31 Dec 2019

Chemical reprogramming of granulosa cells to form functional oocytes

By introducing a chemical cocktail to granulosa cells, researchers in China induced the cells to transform into functional oocytes in mice.

26 Dec 2019

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications.

23 Dec 2019

Researchers develop powerful computer algorithm for large-scale genomic analysis

Haplotypes are a set of genetic variations that, located side by side on the same chromosome, are transmitted in a single group to the next generation. Their examination makes it possible to understand the heritability of certain complex traits, such as the risk of developing a disease.

20 Dec 2019

Using artificial intelligence to disassemble hunting behavior of zebrafish into its components

What is the common ground between making a cup of tea and putting on your shoes? Both actions consist of several movements in a row.

20 Dec 2019

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Scientists create new classification system for tumors

Based on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumors.

19 Dec 2019

First images of new gene editing complex which could upgrade CRISPR

Nobel Prize-winning technique used to capture images of a new gene-editing tool that could improve CRISPR-based tools.

19 Dec 2019

Different mutations in a single gene can have myriad effects on a person's health

Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November.

18 Dec 2019

Researchers identify frequent technical bias in data generated by RNA-seq technology

Reproducibility of research data is a major challenge in experimental biology. As data generated by genomic-scale techniques increases in complexity, this concern is becoming more and more worrisome.

18 Dec 2019

Genomics

The first clinical trials of CRISPR gene editing have shown promising results

Some genetic sequencing misses out large parts of the genome

Using CRISPR to switch off pain gene becomes a possibility with new study

Study uncovers genes controlling mycorrhizal colonization in soybean

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Prison sentences given to scientists who gene-edited babies

Competition between groups has negative effects on wild chimpanzees' reproductive success

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Common plasticizer leads to fertility problems in roundworms

Advancement in reconstitution of the blood system from human pluripotent stem cells

Scientists identify molecules capable of inhibiting DNA methylation, effectively killing malaria parasites

Chemical reprogramming of granulosa cells to form functional oocytes

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

Researchers develop powerful computer algorithm for large-scale genomic analysis

Using artificial intelligence to disassemble hunting behavior of zebrafish into its components

p53 may play a more important role in kidney cancer than previously thought

Scientists create new classification system for tumors

First images of new gene editing complex which could upgrade CRISPR

Different mutations in a single gene can have myriad effects on a person's health

Researchers identify frequent technical bias in data generated by RNA-seq technology

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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