Genomics

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UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

'Genetic scissors' can give rise to unforeseen heritable mutations

CRISPR-Cas9, the "genetic scissors", creates new potential for curing diseases; but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation.

2 Feb 2022

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Your gut bacteria need vitamin B12 just as much as you do. Though DNA is usually passed from parent to child, new research shows gut bacteria transfer genes through "sex" in order to take their vitamins.

2 Feb 2022

Study finds minimal genetic difference between healthy sea stars and those with wasting syndrome

Healthy-looking ochre sea stars have minimal genetic difference from those displaying symptoms of sea star wasting syndrome, say Oregon State University researchers who examined whether genetic variation was the reason some animals went unaffected during an epidemic of the deadly disease.

2 Feb 2022

Dexamethasone administration at a late time point could enhance transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors.

31 Jan 2022

New study on mutation origination fundamentally challenges neo-Darwinism

A new study by a team of researchers from Israel and Ghana has brought the first evidence of nonrandom mutation in human genes, challenging a core assumption at the heart of evolutionary theory by showing a long-term directional mutational response to environmental pressure.

31 Jan 2022

Study identifies high-priority genes associated with uterine cancer that could be potential drug targets

No single gene causes uterine cancer, the fourth most common cancer among women, which is on the rise in the U.S.

28 Jan 2022

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

An international team of researchers led by Karolinska Institutet in Sweden have discovered that a cell type in the central nervous system known as oligodendrocytes might have a different role in the development of multiple sclerosis (MS) than previously thought.

28 Jan 2022

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

A study conducted at the University of Helsinki indicates that early sexual maturation and high aerobic performance in salmon have a genetic link that is already evident in juvenile salmon.

28 Jan 2022

ERGA aims to provide genomic data to inform research about Europe's biodiversity

To provide important genomic data to inform research about Europe's biodiversity, scientists from 48 different countries initiated the "European Reference Genome Atlas" (ERGA) in 2021.

28 Jan 2022

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear.

27 Jan 2022

Diet leaves permanent genetic alterations in the gut microbes

Our gut is inhabited by a diverse community of microbes, the gut microbiota. This community, composed of hundreds of different species, is essential to our health: it influences our immune system, protects us from infections, and helps us digest food.

27 Jan 2022

Genomics

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

'Genetic scissors' can give rise to unforeseen heritable mutations

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Study finds minimal genetic difference between healthy sea stars and those with wasting syndrome

Dexamethasone administration at a late time point could enhance transgene expression

New study on mutation origination fundamentally challenges neo-Darwinism

Study identifies high-priority genes associated with uterine cancer that could be potential drug targets

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

ERGA aims to provide genomic data to inform research about Europe's biodiversity

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

Diet leaves permanent genetic alterations in the gut microbes

New report investigates how genomics could play a part in our lives in the future

New study holds promise to help plants defend themselves against viruses

Study determines how genetics and environmental conditions interact during plant development

Blood proteins could be potential targets for future drugs to slow aging process

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Gene replacement therapy could help mend a broken heart, study suggests

Genetic marker linked to higher risk of death in COVID-19 patients

Study finds more than 1,000 gene-activation differences between female and male mouse brains

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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