Genomics

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Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

20 Jan 2022

Study identifies a new potential pathway for developing therapeutics against Epstein-Barr virus

A new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

19 Jan 2022

New structure prediction method allows scientists to map thousands of secreted proteins

Scientists at the University of California, Berkeley, have recently published work that lays the foundation for new ways of thinking about pathogen evolution.

19 Jan 2022

Rapid DNA sequencing technique used to diagnose rare genetic disease in short time

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours — a feat that's nearly unheard of in standard clinical care.

19 Jan 2022

New method reverses insecticide resistance using CRISPR/Cas9 technology

Insecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year. These insect-specific chemicals, which cost more than $100 million to develop and bring to market, also are critical to controlling insect-driven damage on crops that poses a challenge to food security.

18 Jan 2022

Contagious cancers can jump between marine clam species, study shows

A contagious blood cancer jumped from one species of clam to another and spread among clams living in the Atlantic Ocean and Mediterranean Sea, shows a study published today in eLife.

18 Jan 2022

MD Anderson and Eisbach Bio collaborate to develop precision oncology drugs

The University of Texas MD Anderson Cancer Center and Eisbach Bio GmbH today announced a strategic research collaboration to jointly discover and develop precision oncology drugs that target synthetic lethal engines key to tumor genome evolution.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

University of South Australia scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide.

18 Jan 2022

Earth BioGenome Project moves from pilot projects to full-scale sequencing

A global effort to map the genomes of all plants, animals, fungi and other microbial life on Earth, is entering a new phase as it moves from pilot projects to full-scale production sequencing.

18 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Researchers identify gene variant that protects against severe COVID-19

An international metastudy led by researchers at Karolinska Institutet in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

13 Jan 2022

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

A major new project will investigate how bacterial defenses influence the spread of segments of DNA called mobile genetic elements (MGEs) between bacteria.

13 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours -; a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

Monitoring the presence of enteric pathogens in imported seafood

To monitor the presence of enteric pathogens in imported seafood, the authors of this paper collected a total of 140 seafood samples imported from eight overseas countries from Beijing, Dalian, Shanghai, Guangzhou, and Wuhan seafood markets from June to November 2019.

11 Jan 2022

Study reveals genomic regions that could help understand obesity

A new study has helped to shine light on the genetic pathways underlying obesity. The findings could help develop more personalized ways to help people maintain a healthy weight.

11 Jan 2022

Genomics

Scientists develop new drug delivery system for treating genetic diseases

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Study identifies a new potential pathway for developing therapeutics against Epstein-Barr virus

New structure prediction method allows scientists to map thousands of secreted proteins

Rapid DNA sequencing technique used to diagnose rare genetic disease in short time

New method reverses insecticide resistance using CRISPR/Cas9 technology

Contagious cancers can jump between marine clam species, study shows

MD Anderson and Eisbach Bio collaborate to develop precision oncology drugs

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

Earth BioGenome Project moves from pilot projects to full-scale sequencing

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Study provides valuable insight into the developmental origins of schizophrenia

Researchers identify gene variant that protects against severe COVID-19

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

Monitoring the presence of enteric pathogens in imported seafood

Study reveals genomic regions that could help understand obesity

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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