Genomics

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New genetically based score could help identify young children at high risk of impulsive behavior

While not all impulsive behavior speaks of mental illness, a wide range of mental health disorders which often emerge in adolescence, including depression and substance abuse, have been linked to impulsivity. So, finding a way to identify and treat those who may be particularly vulnerable to impulsivity early in life is especially important.

7 Oct 2022

New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022

Improved brain organoids provide cellular and molecular insights into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids - which are grown in the lab from human cells - provide insights into the brain and uncover differences that may contribute to autism in some people.

6 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

BGI Genomics, in collaboration with Southwest University, the State Key Laboratory of Silkworm Genome Biology, and other partners, has constructed a high-resolution pangenome dataset representing almost the entire genomic content in a silkworm.

30 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Study offers a new glimpse at how DNA variants can impact the lifespan

In a new study of more than 3,000 genetically diverse mice in a multicenter, multiyear project on healthy aging, Maroun Bou Sleiman and colleagues identified several genetic loci that correlate with longevity, offering a new glimpse at how DNA variants can impact the lifespan.

29 Sep 2022

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Yourgene Health plc (“Yourgene”, AIM: YGEN), a leading international molecular diagnostics group, today announced it has received Health Sciences Authority (HSA) approval for its IONA® Nx NIPT Workflow in Singapore.

From Yourgene Health 29 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

NIH launches new program to better understand the function of every human gene

The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.

27 Sep 2022

Study shows how a common epigenetic modification can be transmitted across multiple generations

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development.

27 Sep 2022

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces its continuing commitment to the next generation of researchers and scientists with a call for registrations for its SPRI Grants for Genomic Research.

From Beckman Coulter Life Sciences 27 Sep 2022

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Researchers at the University of California San Diego have for the first time discovered a pattern of DNA mutations that links bladder cancer to tobacco smoking.

27 Sep 2022

Advanced software tool uncovers new cancer-driving genes

An advanced software tool for analyzing DNA sequences from tumor samples has uncovered likely new cancer-driving genes, in a study led by Weill Cornell Medicine researchers.

26 Sep 2022

Researchers identify key gene network responsible for severe tooth enamel defects

Mutations in a certain molecule result in severe damage in the structure and mineral composition of tooth enamel in mice, according to a study conducted at the UZH Center of Dental Medicine.

26 Sep 2022

Viruses exploit ability to sense the environment to maximize their infective yield

New UMBC-led research in Frontiers in Microbiology suggests that viruses are using information from their environment to "decide" when to sit tight inside their hosts and when to multiply and burst out, killing the host cell. The work has implications for antiviral drug development.

23 Sep 2022

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Tiny nets woven from DNA strands can ensnare the spike protein of the virus that causes COVID-19, lighting up the virus for a fast-yet-sensitive diagnostic test – and also impeding the virus from infecting cells, opening a new possible route to antiviral treatment, according to a new study.

23 Sep 2022

Coral genome reveals an alternative pathway for cysteine biosynthesis

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

23 Sep 2022

Genomics

New genetically based score could help identify young children at high risk of impulsive behavior

New platform for gene editing may change the landscape of CRISPR-based therapeutics

Improved brain organoids provide cellular and molecular insights into autism

The involvement of minor intron-containing gene-encoded proteins in viral infections

ASU scientists discover an unusual RNA biogenesis pathway

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

“Mystery gene” matures a main component of the cell skeleton

Study offers a new glimpse at how DNA variants can impact the lifespan

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Novel CRISPR-based method benefits further cancer studies

NIH launches new program to better understand the function of every human gene

Study shows how a common epigenetic modification can be transmitted across multiple generations

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Advanced software tool uncovers new cancer-driving genes

Researchers identify key gene network responsible for severe tooth enamel defects

Viruses exploit ability to sense the environment to maximize their infective yield

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Coral genome reveals an alternative pathway for cysteine biosynthesis

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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