Histology & Microscopy

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Protoporphyrin IX delayed fluorescence imaging as a modality for hypoxia-based oncologic surgical guidance

In the surgical treatment of cancer, distinguishing between tumors and healthy tissues is critical. Fluorescent markers can help to do this, by enhancing the contrast of tumors during surgery.

11 Oct 2022

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

10 Oct 2022

Self-teaching deep learning algorithm can find similar cases in large pathology image repositories

Rare diseases are often difficult to diagnose and predicting the best course of treatment can be challenging for clinicians.

10 Oct 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

Researchers reveal native 3D structure of the ciliary base for the first time

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling.

19 Sep 2022

Researchers use sea anemone to understand how behavior impacts body shape during early development

As humans, we know that an active lifestyle gives us some control over our form. When we hit the pavement, track our steps, and head to the gym, we can maintain muscle development and reduce body fat.

16 Sep 2022

Study reveals cellular underpinnings of motor memory acquisition and consolidation

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best.

14 Sep 2022

New technology reveals cellular changes across neural-epithelial-vascular complex in choroideremia

By combining traditional eye imaging techniques with adaptive optics - a technology that enhances imaging resolution - researchers at the National Eye Institute have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness.

13 Sep 2022

LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Zika virus has a trick up its sleeve. Once inside the body, the virus likes to make a bee line for dendritic cells, the cells we rely on to launch an effective immune response.

12 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Intelligent fluorescent microscope for imaging biological events in detail

Imagine you're a PhD student with a fluorescent microscope and a sample of live bacteria. What's the best way use these resources to obtain detailed observations of bacterial division from the sample?

9 Sep 2022

Novel method can be used to study the resistance profile of bacteria that cause meningitis

A study published in the journal PLOS ONE could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis – an inflammation of the membranes that envelop the brain and spinal cord – are resistant to antibiotics.

6 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer.

From DeNovix Inc. 1 Sep 2022

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

Using organic metal nanohybrid structures to simultaneously identify multiple food poisoning bacteria

Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria.

29 Aug 2022

Histology & Microscopy

Protoporphyrin IX delayed fluorescence imaging as a modality for hypoxia-based oncologic surgical guidance

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Self-teaching deep learning algorithm can find similar cases in large pathology image repositories

Scientists visualize antibiotics in action inside a pathogenic bacterium

Researchers reveal native 3D structure of the ciliary base for the first time

Researchers use sea anemone to understand how behavior impacts body shape during early development

Study reveals cellular underpinnings of motor memory acquisition and consolidation

New technology reveals cellular changes across neural-epithelial-vascular complex in choroideremia

LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Using Q-bodies for imaging intracellular proteins in live cells

Intelligent fluorescent microscope for imaging biological events in detail

Novel method can be used to study the resistance profile of bacteria that cause meningitis

Cell Counting Without Slides to Reduce Waste and Cost

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

Using organic metal nanohybrid structures to simultaneously identify multiple food poisoning bacteria

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inactivation of particular protein complex associated with Parkinson's and anxiety disorders

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Cornell research offers insights into CRISPR RNA-guided Caspase system

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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