Histology & Microscopy

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New ultra-thin photoacoustic endomicroscopy probe can be easily integrated with medical devices

Researchers have created a photoacoustic imaging endoscope probe that can fit inside a medical needle with an inner diameter of just 0.6 millimeters.

28 Jul 2022

Researchers develop new kind of Atomic Force Microscopy probes in true 3D shapes

A team of researchers from NYU Abu Dhabi's Advanced Microfluidics and Microdevices Laboratory (AMMLab) have developed new kind of Atomic Force Microscopy (AFM) probes in true three-dimensional shapes they call 3DTIPs. AFM technology allows scientists to observe, measure, and manipulate samples and micro and nanoscale entities with unprecedented precision.

26 Jul 2022

Genome arrangement of tree ferns offers insights into its evolution

Land plants evolved 470 million years ago from algae and have since reshaped our world. Throughout their evolution, ferns have undergone a series of changes that have helped them survive on land.

25 Jul 2022

Stopping 'budding' viruses in their tracks

Paramyxoviruses have the potential to trigger a devastating pandemic. This family of viruses includes measles, Nipah virus, mumps, Newcastle disease and canine distemper.

20 Jul 2022

Simple, effective method can detect protein misfolding at an early stage of neurodegenerative disease

Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure.

20 Jul 2022

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

19 Jul 2022

Pox viruses deliver proteins that directly interfere with the body's innate immune system

Pox viruses are able to get a head start on infecting a host by delivering a package of proteins that directly interferes with the body's innate immune system.

15 Jul 2022

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Prion diseases are incurable, deadly neurological disorders that can affect both humans and animals–including Creutzfeldt-Jakob Disease (CJD) in people, Bovine Spongiform Encephalopathy (also known as Mad Cow Disease) and Chronic Wasting Disease found in deer.

13 Jul 2022

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.

11 Jul 2022

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

In a discovery that could spur the development of new therapies for more than 40 million HIV patients worldwide, scientists from Rutgers University and the Salk Institute determined the molecular structure of the HIV Pol polyprotein, a protein that plays a critical role in helping the virus propagate itself and spread throughout the body.

7 Jul 2022

Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Urinary tract infections are both very common and potentially very dangerous. More than half of all Australian women will suffer from a UTI in their lifetime, and nearly one in three women will have an infection requiring treatment with antibiotics before the age of 24.

28 Jun 2022

Bacterium discovery helps to solve the puzzle of what factors limit cell size

On sunken leaves in the waters of a Caribbean mangrove swamp, researchers discovered a bacterium that challenges the prevailing view of bacterial cell size; counter to the notion that microbes are only visible with a microscope, this one – named Thiomargarita magnifica – is larger than all other known giant bacteria by ~50-fold, and can be seen by the naked eye, the study's authors say.

23 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

Bruker Corporation today announced the release of the NeuraLight 3D Ultra™ module to support advanced neuroscience and optogenetics research applications on Bruker’s Ultima multiphoton microscopes.

From Bruker Nano Surfaces and Metrology 16 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

Histology & Microscopy

New ultra-thin photoacoustic endomicroscopy probe can be easily integrated with medical devices

Researchers develop new kind of Atomic Force Microscopy probes in true 3D shapes

Genome arrangement of tree ferns offers insights into its evolution

Stopping 'budding' viruses in their tracks

Simple, effective method can detect protein misfolding at an early stage of neurodegenerative disease

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Pox viruses deliver proteins that directly interfere with the body's innate immune system

Prion imaging could lead to better understanding of what causes fatal neurological disorders

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Bacterium discovery helps to solve the puzzle of what factors limit cell size

Study unveils a precise model for the stinging organelle of starlet sea anemone

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Deciphering the structure of nuclear pore complex piece by piece

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Color-changing mouse model aids in better visualization of internal physiology

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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