Histology & Microscopy

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Utilizing AI to Accelerate the Field of High Content Analysis

In this interview, we speak to Araceli Biosciences about their latest product the Araceli Endeavor, and how its revolutionizing the field of high content screening.

From Society for Laboratory Automation and Screening (SLAS) 29 Mar 2022

Study shows how cells use octopus-like tentacles to move around the body

With help from the best tweezers in the world a team of researchers from the University of Copenhagen has shed new light on a fundamental mechanism in all living cells that helps them explore their surroundings and even invade tissue.

28 Mar 2022

Quantum dots can quantify specific types of cells inside deep tissues of the body

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body.

23 Mar 2022

Predatory bacterium can sculpt its own shape to fit inside the prey

Scientists have found that a predatory bacterium, capable of invading and consuming harmful bugs such as E.coli and Salmonella, can sculpt its own shape to fit inside its prey.

22 Mar 2022

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

21 Mar 2022

Optical coherence tomography reveals the beating and development of human heart organoids

Researchers have been using organoids - 3D organ-like, tightly-packed cell cultures - as models to study organ development, disease and drug discovery with excellent success.

16 Mar 2022

Bacteria change their morphology when acquiring drug resistance, study reveals

If you've been hitting the gym and getting results, you know it's time to strut your stuff; and it turns out bacteria feel the same way.

15 Mar 2022

Conformational variation of the SARS-CoV-2 energy landscape

Researchers demonstrate that the energy landscape of SARS-CoV-2 exhibits significant conformational variation.

14 Mar 2022

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

Researchers at UC San Diego's Scripps Institution of Oceanography have discovered a novel molecular process that corals use to control the subcellular environment of the algae that live inside them.

11 Mar 2022

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Two University of Houston researchers are developing a type of spectroscopy to help understand how ribosomes make proteins deep within cells, the discovery of which could potentially guide drug design to treat cancers and viral infections.

8 Mar 2022

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk.

4 Mar 2022

Study may pave the way for better multiple sclerosis drugs

Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.

4 Mar 2022

New micro-protein supports cell division and proliferation during nutrient scarcity

Researchers from the University of Eastern Finland and the University of Montreal (Canada) have discovered that a micro-protein, which they named Nrs1, supports cell division and proliferation when nutrients are scarce.

4 Mar 2022

Discovery provides a more precise picture of the retina's optical properties

Researchers at the National Eye Institute (NEI) have discovered that power-producing organelles in the eye's photoreceptor cells, called mitochondria, function as microlenses that help channel light to these cells' outer segments where it's converted into nerve signals.

2 Mar 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Spectacular structure of C.difficile's protective armor revealed

The spectacular structure of the protective armor of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

25 Feb 2022

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown.

25 Feb 2022

Real-time imaging shows cells of developing fruit fly eye move into position

The ability of cells to self-organize into specific patterns in tissues that serve a function is a universal feature of life.

23 Feb 2022

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

Histology & Microscopy

Utilizing AI to Accelerate the Field of High Content Analysis

Study shows how cells use octopus-like tentacles to move around the body

Quantum dots can quantify specific types of cells inside deep tissues of the body

Predatory bacterium can sculpt its own shape to fit inside the prey

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

Optical coherence tomography reveals the beating and development of human heart organoids

Bacteria change their morphology when acquiring drug resistance, study reveals

Conformational variation of the SARS-CoV-2 energy landscape

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

UH researchers receive grant for developing new imaging technique to peer into ribosomes

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

Study may pave the way for better multiple sclerosis drugs

New micro-protein supports cell division and proliferation during nutrient scarcity

Discovery provides a more precise picture of the retina's optical properties

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Spectacular structure of C.difficile's protective armor revealed

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Real-time imaging shows cells of developing fruit fly eye move into position

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers unravel essential final steps in the production of mRNA

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

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