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Famous painters, musicians, and writers who fought against neurological disorders

The third part of Neurological Disorders in Famous Artists presents painters, musicians, and writers who had to fight against an acute or chronic neurological disease. Sometimes this fight was without success (e.g. Shostakovich, Schumann, Wolf, Pascal), but often a dynamic and paradoxical creativity of the clinical disorder was integrated into their artistic production (e.g. Klee, Ramuz).

29 May 2010

RNAi therapy shuts down gene critical to RSV, prevents virus replication

John DeVincenzo, MD, professor and researcher in the Departments of Pediatrics and Molecular Sciences at the University of Tennessee Health Science Center (UTHSC), has proven for the first time that a totally new concept in drug design can be used to treat human disease. Dr. DeVincenzo, who also serves as a children's infectious diseases specialist at Le Bonheur Children's Hospital, conducted his study at the Children's Foundation Research Center, a UT Health Science Center partner located at Le Bonheur.

29 May 2010

Study demonstrates protection against Ebola infection in nonhuman primates using RNAi

Scientists using tiny particles of genetic material to interfere in the replication process of the deadly Ebola virus have successfully prevented monkeys exposed to that virus from dying of hemorrhagic fever. The proof-of-concept study, published in this week's issue of The Lancet, suggests that such protection also should be possible in humans.

29 May 2010

Preimplantation Factor essential for pregnancy to succeed: Study

Researchers at Yale School of Medicine and their colleagues at the Society for the Investigation of Early Pregnancy have helped clarify the function of a unique protein called Preimplantation Factor, which is produced by healthy embryos to direct embryo attachment and help the mother adapt to pregnancy.

29 May 2010

Allergic reactions prevent people with allergic asthma from generating healthy immune response to influenza

New research from UT Southwestern Medical Center suggests that allergic reactions to pet dander, dust mites and mold may prevent people with allergic asthma from generating a healthy immune response to respiratory viruses such as influenza.

29 May 2010

New, non-controversial source of stem cells can form heart muscle cells, repair heart damage

A new and non-controversial source of stem cells can form heart muscle cells and help repair heart damage, according to results of preliminary lab tests reported in Circulation Research: Journal of the American Heart Association.

29 May 2010

Pancreatic cancer patients with circulating tumor cells tend to have worse outcomes: Study

Fox Chase Cancer Center investigators find that pancreatic cancer patients who have circulating tumor cells tend to have worse outcomes than patients without circulating tumor cells. Additionally, the team has uncovered evidence that not all circulating tumor cells are the same, and some may predict worse outcomes than others.

29 May 2010

Novel pipette technique for study of structural properties of tissues

A collaboration of French and Canadian researchers have found that sucking a portion of a spherical globule of cells into a tiny pipette provides information about the adhesion between cells and the elastic properties of the tissue. The method is a novel approach for the study of the structural properties of tissues, and should offer insights into processes such as embryonic development, tissue growth and cancer. A paper describing the research appears online in Physical Review Letters on May 24.

28 May 2010

Researchers discover bitter taste inhibitor

Researchers have discovered a chemical that specifically blocks people's ability to detect the bitter aftertaste that comes with artificial sweeteners such as saccharin. The key is a molecule known only as GIV3727 that specifically targets and inhibits a handful of human bitter taste receptors, according to a report published online on May 27th in Current Biology, a Cell Press publication.

28 May 2010

Study papers shows how nutrients affect gene expression

Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system.

28 May 2010

Novel imaging system helps visualize and monitor cellular immune responses of transplanted tissue in real time

A group of "color-coded" laboratory mice are providing researchers with a novel way of tracking T-cells, enabling them to visualize and monitor the cellular immune responses of transplanted tissue in real time. The new imaging system is described in the June issue of Nature Medicine, which appears on-line this week.

28 May 2010

Helicobacter pylori's helical shape helps it colonize the stomach

The bacterium Helicobacter pylori, which lives in the human stomach and is associated with ulcers and gastric cancer, is shaped like a corkscrew, or helix. For years researchers have hypothesized that the bacterium's twisty shape is what enables it to survive - and thrive - within the stomach's acid-drenched environment, but until now they have had no proof.

28 May 2010

Amorfix, Aragen Bioscience collaborate to develop high-affinity monoclonal antibodies against targets for cancer

Amorfix Life Sciences and Aragen Bioscience, Inc. announced today that they have entered into an agreement to develop high-affinity monoclonal antibodies against a number of targets for cancer. Using its proprietary ProMIS(TM) computational platform discovery technology, Amorfix has identified several disease specific epitopes ("DSEs") on misfolded Fas receptor. Aragen will use those DSEs to generate highly specific monoclonal antibodies ("mAbs").

28 May 2010

Advocates urge Congress to reauthorize C.W. Bill Young Cell Transplantation Program and NCBI

More than 60 adult donors, transplant recipients, family members and medical professionals from 25 states met with lawmakers and staff on Capitol Hill today to urge Congress for increased federal funding to grow and diversify the national registry of adult donors and publicly available cord blood units as part of the C.W. Bill Young Transplantation Program and the National Cord Blood Inventory.

28 May 2010

New study provides cause-and-effect link between immune system cells and mental illness

A Nobel Prize-winning University of Utah geneticist discovered that bone marrow transplants cure mutant mice who pull out their hair compulsively. The study provides the first cause-and-effect link between immune system cells and mental illness, and points toward eventual new psychiatric treatments.

28 May 2010

Research finding could lead to first-ever target for drug therapy for lymphedema

A genetic mutation for inherited lymphedema associated with lymphatic function has been discovered that could help create new treatments for the condition, say researchers at the University of Pittsburgh Graduate School of Public Health. Their findings are reported in the June issue of the American Journal of Human Genetics.

28 May 2010

NeoStem to present adult stem cell technologies at Stem Cell Investor & Executive Networking Conference

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, announced that the Company has been invited to present its adult stem cell technologies at the Stem Cell Investor & Executive Networking Conference Event (SCIENCE) in New York City on June 1, 2010. SCIENCE is designed to bring together investors with industry executives, visionary researchers and clinicians and other stakeholders to highlight opportunities and discuss advances in the stem cell field.

28 May 2010

Cardiac biomarkers help nephrologists manage fluid overload in dialysis patients: Study

Nephrologists must consider fluid overload effects when prescribing dialysis, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology. The fluid overload biomarker, N-terminal pro-brain-type natriuretic peptide, previously known as a "cardiac biomarker" in dialysis patients, is an important component of managing patients with kidney disease.

28 May 2010

BG Medicine announces data presentations on galectin-3 at Heart Failure Congress 2010

BG Medicine, Inc., a U.S. based, privately-held biomarker discovery and in vitro diagnostics company, announced today that there will be several data presentations regarding galectin-3 at the Heart Failure Congress 2010, the annual scientific meeting of the Heart Failure Association of the European Society of Cardiology, to be held in Berlin, Germany, on May 29th through June 1st. BG Medicine has developed and applied for FDA clearance of an in vitro diagnostic test to measure galectin-3 levels in plasma or serum.

28 May 2010

Small molecule ramps up interferon production in host cells, launching potent immune response

Many disease-causing microbes carry pumps that expel antibiotics, making the bugs hard to kill with standard drugs. Ironically, these same pumps could be the bugs' Achilles heel.

28 May 2010

Medical Science News

Famous painters, musicians, and writers who fought against neurological disorders

RNAi therapy shuts down gene critical to RSV, prevents virus replication

Study demonstrates protection against Ebola infection in nonhuman primates using RNAi

Preimplantation Factor essential for pregnancy to succeed: Study

Allergic reactions prevent people with allergic asthma from generating healthy immune response to influenza

New, non-controversial source of stem cells can form heart muscle cells, repair heart damage

Pancreatic cancer patients with circulating tumor cells tend to have worse outcomes: Study

Novel pipette technique for study of structural properties of tissues

Researchers discover bitter taste inhibitor

Study papers shows how nutrients affect gene expression

Novel imaging system helps visualize and monitor cellular immune responses of transplanted tissue in real time

Helicobacter pylori's helical shape helps it colonize the stomach

Amorfix, Aragen Bioscience collaborate to develop high-affinity monoclonal antibodies against targets for cancer

Advocates urge Congress to reauthorize C.W. Bill Young Cell Transplantation Program and NCBI

New study provides cause-and-effect link between immune system cells and mental illness

Research finding could lead to first-ever target for drug therapy for lymphedema

NeoStem to present adult stem cell technologies at Stem Cell Investor & Executive Networking Conference

Cardiac biomarkers help nephrologists manage fluid overload in dialysis patients: Study

BG Medicine announces data presentations on galectin-3 at Heart Failure Congress 2010

Small molecule ramps up interferon production in host cells, launching potent immune response

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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