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Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

A Florida State University College of Medicine researcher has discovered a new interaction between a cell signaling system and a specific gene that may be the cause of B-cell lymphoma. The finding suggests a similar interaction could be occurring during the development of other types of cancer, leading to further understanding of how cancer works — and how it might be stopped.

28 May 2010

Progenics presents preclinical data on novel monoclonal antibodies against toxins produced by C. difficile

Progenics Pharmaceuticals, Inc. today announced the presentation of preclinical data on novel monoclonal antibodies against toxins produced by the bacterium Clostridium difficile (C. difficile). The monoclonal antibodies effectively neutralized the cell-killing activities of the toxins in vitro and significantly improved survival in a stringent animal model of C. difficile infection. C. difficile is the leading cause of hospital-acquired diarrhea in the United States and represents a growing global public health challenge.

28 May 2010

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions.

28 May 2010

E. coli O157:H7 is rare in some wildlife species of California's Central Coast region: Researchers

The disease-causing bacterium E. coli O157:H7 is present but rare in some wildlife species of California's agriculturally rich Central Coast region, an area often referred to as the nation's "salad bowl," reports a team or researchers led by a UC Davis scientist.

28 May 2010

Regulus Therapeutics obtains rights to intellectual property covering methods for modulating microRNA-21

Regulus Therapeutics Inc. announced today that it has obtained exclusive rights from the University of Wuerzburg to intellectual property covering methods for modulating microRNA-21. Regulus scientists and collaborators have shown that microRNA-21, (miR-21), is dysregulated in mouse models of cardiac disease and fibrosis, and that antagonizing miR-21 with therapeutic oligonucleotides targeting miR-21 inhibits fibrosis and attenuates cardiac function in such models. Regulus is currently developing a microRNA therapeutic targeting miR-21 as an anti-fibrotic therapy.

28 May 2010

Bone marrow transplant cures excessive pathological grooming behavior in mice

Scientists earlier found that mice missing one of a group of core developmental genes known as the Hox genes developed an odd and rather unexpected pathology: the mutant animals groomed themselves compulsively to the point that they were removing their own hair and leaving self-inflicted open sores on their skin. Now, they've found a surprising connection between the Hoxb8 gene and the behavior that looks an awful lot like that of people with an obsessive compulsive spectrum disorder (OCD).

28 May 2010

CDP-choline may block skull and brain damage that result from alcohol consumption early in pregnancy

The dietary supplement CDP-choline, sold as a brain-boosting agent and under study for stroke and traumatic brain injury, may block skull and brain damage that can result from alcohol consumption early in pregnancy, Medical College of Georgia researchers report.

28 May 2010

OHSU partners with UO, Harvard to expedite research into compounds that may prevent Fanconi anemia

Oregon Health & Science University is partnering with the University of Oregon and Harvard Medical School to expedite basic science research into new and existing drugs and compounds that may prevent the complications associated with Fanconi anemia, an inherited condition that can lead to bone marrow failure and cancer.

28 May 2010

Research finding may offer future alternative to antibiotics

A team of scientists from government, academia and private industry has developed a novel treatment that protects mice from infection with the bacterium that causes tularemia, a highly infectious disease of rodents, sometimes transmitted to people, and also known as rabbit fever. In additional experiments with human immune cells, the treatment also demonstrated protection against three other types of disease-causing bacteria that, like the tularemia bacteria, occur naturally, can be highly virulent, and are considered possible agents of bioterrorism.

28 May 2010

Applied Biocode receives CE Certified marking for BioCode-1000 Analyzer

Applied BioCode, Inc. announced that its BioCode-1000 Analyzer has been CE Certified under the compliance of Laboratory Equipment Standards EN55011, EN61010-1, EN61326-1, IEC61010, EN61000-3-2, and EN61000-3-3. The CE Certified marking that the BioCode-1000 Analyzer has met all relevant European Union consumer safety requirements.

28 May 2010

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

Scientists are reporting development of a fast, simple, inexpensive method for determining whether chemicals in consumer products and workplaces may cause skin allergies in people -- a method that does not involve use of animals. Their study appears in ACS' Chemical Research in Toxicology, a monthly journal.

27 May 2010

Leading stem cell scientists to discuss on stem cell clinical trials for ALS and heart attack patients

The first Cedars-Sinai Regenerative Medicine Scientific Symposium, dedicated to furthering our ability to bring stem cell therapies from the laboratory to the patient bedside. The conference, led by Clive Svendsen, Ph.D., and Eduardo Marb-n, M.D., Ph.D., will highlight the most recent developments in leading-edge stem cell research and treatments for brain and heart diseases.

27 May 2010

Genentech uses Complete Genomics' sequencing service to compare primary lung tumor, adjacent normal tissue

Complete Genomics Inc., a third-generation human genome sequencing company, today announced that Genentech Inc., a wholly owned member of the Roche Group, used the company's sequencing, bioinformatics and analytics services to sequence and compare a patient's primary lung tumor and adjacent normal tissue.

27 May 2010

Study of GCF advances efforts to develop early test for gum disease

A little-known fluid produced in tiny amounts in the gums, those tough pink tissues that hold the teeth in place, has become a hot topic for scientists trying to develop an early, non-invasive test for gum disease, the No. 1 cause of tooth loss in adults. It's not saliva, a quart of which people produce each day, but gingival crevicular fluid (GCF), produced at the rate of millionths of a quart per tooth. The study, the most comprehensive analysis of GCF to date, appears in ACS' monthly Journal of Proteome Research.

27 May 2010

Oregon State University researchers make fundamental advance in robotics

Researchers at Oregon State University have made an important fundamental advance in robotics, in work that should lead toward robots that not only can walk and run effectively, but use little energy in the process.

27 May 2010

Abnormal androgen signaling in ovaries cause female infertility

Male sex hormones, such as testosterone, have well defined roles in male reproduction and prostate cancer. What may surprise many is that they also play an important role in female fertility. A new study finds that the presence and activity of male sex hormones in the ovaries helps regulate female fertility, likely by controlling follicle growth and development and preventing deterioration of follicles that contain growing eggs.

27 May 2010

Tendons in high-stress areas repair themselves less frequently than low-stress tendons: Study

In a discovery that seems counterintuitive, a study appearing in the May 21st Journal of Biological Chemistry has found that tendons in high-stress and strain areas, like the Achilles tendon, actually repair themselves less frequently than low-stress tendons. This study sheds some light on the increased susceptibility of certain tendons to injury during aging.

27 May 2010

Blocking the activity of death receptor can stop tumor growth: New research study

Every cell contains machinery for self-destruction, used to induce death when damaged or sick. But according to a new research study, a receptor thought to mediate cell suicide in normal cells may actually be responsible for the unrestrained growth of cancerous tumors.

27 May 2010

Blocking the activity of PAT proteins stops cancer cell growth: Scientists

Cancer Research UK-funded scientists have revealed that a set of proteins act as the cell's 'nose' to 'sniff out' molecules which trigger cell growth, according to research published in Oncogene today.

27 May 2010

UCI scientists create eight-layer, early-stage retina from human embryonic stem cells

UC Irvine scientists have created an eight-layer, early-stage retina from human embryonic stem cells, the first three-dimensional tissue structure to be made from stem cells.

27 May 2010

Medical Science News

Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

Progenics presents preclinical data on novel monoclonal antibodies against toxins produced by C. difficile

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

E. coli O157:H7 is rare in some wildlife species of California's Central Coast region: Researchers

Regulus Therapeutics obtains rights to intellectual property covering methods for modulating microRNA-21

Bone marrow transplant cures excessive pathological grooming behavior in mice

CDP-choline may block skull and brain damage that result from alcohol consumption early in pregnancy

OHSU partners with UO, Harvard to expedite research into compounds that may prevent Fanconi anemia

Research finding may offer future alternative to antibiotics

Applied Biocode receives CE Certified marking for BioCode-1000 Analyzer

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

Leading stem cell scientists to discuss on stem cell clinical trials for ALS and heart attack patients

Genentech uses Complete Genomics' sequencing service to compare primary lung tumor, adjacent normal tissue

Study of GCF advances efforts to develop early test for gum disease

Oregon State University researchers make fundamental advance in robotics

Abnormal androgen signaling in ovaries cause female infertility

Tendons in high-stress areas repair themselves less frequently than low-stress tendons: Study

Blocking the activity of death receptor can stop tumor growth: New research study

Blocking the activity of PAT proteins stops cancer cell growth: Scientists

UCI scientists create eight-layer, early-stage retina from human embryonic stem cells

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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