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Study indicates dogs make excellent models for studying human genetic disorders

In the new Swedish-Finnish study, published in Nature Genetics, the researchers identified five loci that predispose to an SLE-related disease in Nova Scotia duck tolling retrievers.

31 Jan 2010

USPTO allows claims to Rosetta Genomics' two microRNA related patent applications

Rosetta Genomics today announced that the United States Patent and Trademark Office has allowed claims in two patent applications.

30 Jan 2010

Delaware Bio members support bioscience educational initiatives

Last night at the second annual Delaware Bio Winterfest, Delaware BioScience Association provided the Junior Achievement of Delaware with financial support of $6555.00 to aid in the outfitting of the new Innovation hub.

30 Jan 2010

Noninvasive optical imaging probes to determine amount and type of cell death in tumors

For quite some time, the "Holy Grail" in medical imaging has been the development of an effective method to image cell death as a means to intervene early in diseases and rapidly determine the effectiveness of treatments. A new paper by researchers at the University of Notre Dame and the Washington University School of Medicine describes important progress in using a synthetic probe to target dead and dying cells in mammary and prostate tumors in living animals.

30 Jan 2010

Musical video to teach basics of biotechnology

The video will be made available to high school students across North Carolina to help teach them how biotechnology harnesses cellular machinery to cure diseases, detect biohazards and manufacture new materials.

30 Jan 2010

Pathway Genomics' genetic health report provides valuable insight into certain health conditions

In the past few years, the science of genetic testing has advanced exponentially, both in the amount of information genetic testing can reveal and the precision and reliability of the results.

30 Jan 2010

Study may lead to preventative and therapeutic treatments for MS patients

Previous studies have shown multiple sclerosis (MS) patients are more often born in spring than in any other season, indicating that there is an environmental risk factor for the disease. A paper in the journal Neurology, reviewed for f1000 Medicine by Emmanuelle Waubant and Ellen Mowry, now suggests that this seasonal effect is mediated by the gene HLA-DRB1.

30 Jan 2010

New biomarker may predict treatment outcomes in RA patients

Investigators have identified a biomarker that could help doctors select patients with rheumatoid arthritis who will benefit from therapy with drugs such as Enbrel, a tumor necrosis factor (TNF)-antagonist drug.

30 Jan 2010

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types. Researchers in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Beno-t J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer-assisted structure-based drug design. The study was presented in the January 2010 online issue of the Journal of Medicinal Chemistry.

30 Jan 2010

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

A new study from UC Davis Health System identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons.

30 Jan 2010

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

Cervical cancer is highly curable when caught early. But in a third of cases, the tumor responds poorly to therapy or recurs later, when cure is much less likely.

29 Jan 2010

BBVA Foundation Frontiers of Knowledge Award granted to Robert J. Lefkowitz

The BBVA Foundation Frontiers of Knowledge Award in the Biomedicine category goes in this second edition to Prof. Robert J. Lefkowitz (1943, New York, United States), investigator in the Department of Medicine at Duke University (United States).

29 Jan 2010

Nectar of almond tree produces amygdalin

The nectar of the almond tree produces an extraordinary and dangerous poison. This is the only known plant to have this poison in its flowers' nectar. A study carried out at the University of Haifa has revealed that bees are mysteriously drawn to the toxic substance.

29 Jan 2010

Discovery may help in designing drugs for sun-damaged skin

Researchers at Ohio State University have found a new way to study how enzymes move as they repair DNA sun damage -- and that discovery could one day lead to new therapies for healing sunburned skin.

29 Jan 2010

Targeted sequencing of exome can help identify potential disease-causing genes

Researchers from University of Miami Miller School of Medicine and Roche Applied Science have recently published a research study on human exome resequencing results from eight individuals that span across three generations of a family. The findings of this study showcased the value of targeted enrichment for family-based studies which allows researchers to quickly identify potential disease-causing genetic variants and will provide the data and information for further research to better understand disease and the impact across generations of a family.

29 Jan 2010

GSA announces recipients of 2010 awards for distinguished service in the field of genetics

The Genetics Society of America (GSA) is pleased to announce the recipients of its five awards for distinguished service to the field of genetics. These awards represent sustained activity and contributions by members of the genetics community.

29 Jan 2010

New understanding of CD44 receptor's role in immune cell survival

Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a new way the cell surface protein, CD44, helps specific T helper (Th1) cells develop immunologic memory.

29 Jan 2010

Experimental vaccine protects mice and monkeys against chikungunya virus

An experimental vaccine developed using non-infectious virus-like particles (VLP) has protected macaques and mice against chikungunya virus, a mosquito-borne pathogen that has infected millions of people in Africa and Asia and causes debilitating pain, researchers at the National Institutes of Health have found.

29 Jan 2010

Findings could guide in developing more effective vaccines for HIV/AIDS and cancer

In an acute viral infection, most of the white blood cells known as T cells differentiate into cells that fight the virus and die off in the process. But a few of these "effector" T cells survive and become memory T cells, ensuring that the immune system can respond faster and stronger the next time around.

29 Jan 2010

Normal protein can be converted into prion that causes fatal brain diseases in humans

Scientists have determined how a normal protein can be converted into a prion, an infectious agent that causes fatal brain diseases in humans and mammals.

29 Jan 2010

Medical Science News

Study indicates dogs make excellent models for studying human genetic disorders

USPTO allows claims to Rosetta Genomics' two microRNA related patent applications

Delaware Bio members support bioscience educational initiatives

Noninvasive optical imaging probes to determine amount and type of cell death in tumors

Musical video to teach basics of biotechnology

Pathway Genomics' genetic health report provides valuable insight into certain health conditions

Study may lead to preventative and therapeutic treatments for MS patients

New biomarker may predict treatment outcomes in RA patients

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

BBVA Foundation Frontiers of Knowledge Award granted to Robert J. Lefkowitz

Nectar of almond tree produces amygdalin

Discovery may help in designing drugs for sun-damaged skin

Targeted sequencing of exome can help identify potential disease-causing genes

GSA announces recipients of 2010 awards for distinguished service in the field of genetics

New understanding of CD44 receptor's role in immune cell survival

Experimental vaccine protects mice and monkeys against chikungunya virus

Findings could guide in developing more effective vaccines for HIV/AIDS and cancer

Normal protein can be converted into prion that causes fatal brain diseases in humans

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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