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Combination of chemotherapy and midostaurin drug may benefit AML patients with FLT3 mutations

A targeted drug that is active against acute myeloid leukemia (AML) is particularly effective when teamed with chemotherapy in patients whose cancer cells harbor a key genetic mutation, researchers at Dana-Farber Cancer Institute and their colleagues will report at the American Society of Hematology's (ASH) annual meeting on Monday, Dec. 7 (Ernest N. Morial Convention Center, Room 343-345, 5:15 pm CT).

8 Dec 2009

New bone marrow transplantation technique shows prompt immune recovery

Although bone marrow transplants have long been standard for acute leukemia, current treatments still rely on exact matches between donor and patient. Now, scientists at the University of Perugia, Italy, and the Weizmann Institute of Science have improved on a method of transplanting bone marrow-based stem cells from a mismatched donor, making it safer for use when no exact match exists.

8 Dec 2009

New research discovers link between HIV-related cognitive deficits and Alzheimer's-related dementia

More than half of HIV patients experience memory problems and other cognitive impairments as they age, and doctors know little about the underlying causes. New research from Washington University School of Medicine in St. Louis suggests HIV-related cognitive deficits share a common link with Alzheimer's-related dementia: low levels of the protein amyloid beta in the spinal fluid.

8 Dec 2009

Prenatal exposure to microbes may help protect child from developing allergies later in life

A pregnant woman's exposure to microbes may protect her child from developing allergies later in life. Researchers in Marburg, Germany find that exposure to environmental bacteria triggers a mild inflammatory response in pregnant mice that renders their offspring resistant to allergies.

8 Dec 2009

Aston University researchers receive stimulus funds to study fundamental processes of human vision

A team of researchers led by Professor Mark Georgeson and Dr Timothy Meese at Aston University in Birmingham, UK have been awarded over £1 million pounds worth of funding from the BBSRC (Biotechnology and Biological Sciences Research Council) and the EPSRC (Engineering and Physical Sciences Research Council) to investigate some of the fundamental processes involved in human vision.

8 Dec 2009

Researchers identify gene expression and biological pathways for healing gingivitis

Gingivitis, which may affect more than one-half of the U.S. adult population, is a condition commonly attributed to lapses in simple oral hygiene habits. However, a new study shows that development and reversal of gingivitis at the molecular level is apparently much more complicated than its causes might indicate.

8 Dec 2009

Social isolation and stress can raise breast cancer risk

Social isolation and related stress could contribute to human breast cancer susceptibility, research from a rat model designed at the University of Chicago to identify environmental mechanisms contributing to cancer risk shows.

8 Dec 2009

iRGD peptide found to enhance both cancer detection and treatment

Researchers at Burnham Institute for Medical Research at University of California, Santa Barbara have identified a peptide (a chain of amino acids) that specifically recognizes and penetrates cancerous tumors but not normal tissues.

8 Dec 2009

Cyntellect and Boston University sign research collaboration agreement

Cyntellect, Inc., a privately-held life sciences company commercializing products to advance life science and stem cell research, biopharmaceutical production, and drug discovery, today announced it has entered into a research collaboration agreement with the Boston University School of Medicine.

8 Dec 2009

Caffeinated energy drink does not neutralize alcohol intoxication, says new study

People who drink may want to know that coffee won't sober them up, according to new laboratory research. Instead, a cup of coffee may make it harder for people to realize they're drunk.

8 Dec 2009

Multi-institutional team explores regenerative techniques for injured spinal cords

For more than 400 years, scientists have studied the amazing regenerative power of salamanders, trying to understand how these creatures routinely repair injuries that would usually leave humans and other mammals paralyzed - or worse.

8 Dec 2009

Study shows positive association between adolescent fitness and cognitive performance

In the first study to demonstrate a clear positive association between adolescent fitness and adult cognitive performance, Nancy Pedersen of the University of Southern California and colleagues in Sweden find that better cardiovascular health among teenage boys correlates to higher scores on a range of intelligence tests - and more education and income later in life.

8 Dec 2009

Cysteine-rich whey protein supplement may maintain or increase weight in advanced NSCLC patients

Immunotec Inc. announced today the enrollment of the first patient in the US Cancer trial of IMN 1207 being run at Beaumont Hospital's Community Clinical Oncology Program (CCOP) in Royal Oak, Michigan. The goal of the study is to determine the effect of IMN 1207, a cysteine-rich whey protein supplement, in preventing additional weight loss in patients with stage IV (advanced) non-small cell lung cancer.

7 Dec 2009

PharmAthene presents Protexia clinical trial results at PHEMCE conference

PharmAthene, Inc., a biodefense company developing medical countermeasures against biological and chemical threats, today announced Phase I clinical trial results for Protexia, a pegylated recombinant version of human butyrylcholinesterase (rBChE), which has been shown to be effective in animal models in preventing toxicity from exposure to chemical nerve agents.

7 Dec 2009

Cytometry system to precisely control cell movement using sound waves

Applied Biosystems, part of Life Technologies Corporation today announced its entry into the flow cytometry instrumentation market with the debut of the Attune™ Acoustic Focusing Cytometer, a first of its kind cytometry system designed to use sound waves to precisely control the movement of cells.

7 Dec 2009

New study reveals RNA may play a critical role in cancer treatment

Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a big role in cancer treatment, and provides hope for future patients battling one of the most prevalent and difficult to treat cancers.

7 Dec 2009

Computer search algorithms identify FDA-approved drugs that could be the basis for new medicines

A massive, data-crunching computer search program that matches fragments of potential drug molecules to the known shapes of viral surface proteins has identified several FDA-approved drugs that could be the basis for new medicines -- if emerging viruses such as the H5N1(avian flu) or H1N1/09 (swine flu) develop resistance to current antiviral therapies -- according to a presentation at the American Society for Cell Biology (ASCB) 49th Annual Meeting, Dec. 5-9, 2009 in San Diego.

7 Dec 2009

Scientists identify aggression-promoting pheromone in flies’ antenna

Have you ever found yourself struggling to get your order taken at a crowded bar or lunch counter, only to walk away in disgust as more aggressive customers elbow their way to the front? It turns out that flies do much the same thing, according to biologists from the California Institute of Technology (Caltech).

7 Dec 2009

Scientists explore new strategies for treating neurodegenerative diseases

Studies with fruit flies have shown that the specialized nerve cells called neurons can rebuild themselves after injury.

7 Dec 2009

Albert Einstein College of Medicine receives SU2C grant for cancer research

Matthew Levy, Ph.D., assistant professor of biochemistry at Albert Einstein College of Medicine of Yeshiva University, has been awarded more than $700,000 by Stand Up To Cancer (SU2C) for his high-risk/high-reward cancer research.

7 Dec 2009

Medical Science News

Combination of chemotherapy and midostaurin drug may benefit AML patients with FLT3 mutations

New bone marrow transplantation technique shows prompt immune recovery

New research discovers link between HIV-related cognitive deficits and Alzheimer's-related dementia

Prenatal exposure to microbes may help protect child from developing allergies later in life

Aston University researchers receive stimulus funds to study fundamental processes of human vision

Researchers identify gene expression and biological pathways for healing gingivitis

Social isolation and stress can raise breast cancer risk

iRGD peptide found to enhance both cancer detection and treatment

Cyntellect and Boston University sign research collaboration agreement

Caffeinated energy drink does not neutralize alcohol intoxication, says new study

Multi-institutional team explores regenerative techniques for injured spinal cords

Study shows positive association between adolescent fitness and cognitive performance

Cysteine-rich whey protein supplement may maintain or increase weight in advanced NSCLC patients

PharmAthene presents Protexia clinical trial results at PHEMCE conference

Cytometry system to precisely control cell movement using sound waves

New study reveals RNA may play a critical role in cancer treatment

Computer search algorithms identify FDA-approved drugs that could be the basis for new medicines

Scientists identify aggression-promoting pheromone in flies’ antenna

Scientists explore new strategies for treating neurodegenerative diseases

Albert Einstein College of Medicine receives SU2C grant for cancer research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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