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Emerging concepts from gene regulation studies in immune cells

The seventh meeting in the “Emergence and Convergence” series jointly organized by La Fondation IPSEN and Nature brings together today in San Antonio (Texas, USA) leading experts to discuss concepts emerging from gene regulation studies in immune cells that have led to insights into the initiation and maintenance of epigenetic chromatin marks necessary for proper differentiation and function of these cells in the immune system.

19 Feb 2010

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Malaria remains one of the most deadly infectious diseases. Yet, how Plasmodium, the malaria parasite, regulates its infectious cycle has remained an enigma despite decades of rigorous research.

19 Feb 2010

Study shows how genes and environmental factors influence common human diseases

A UCLA study reveals how human genes interact with their environment to boost disease risk. Published in the Feb. 18 online edition of the American Journal of Human Genetics, the findings shed light on why the search for specific gene variants linked to human diseases can only partly explain common disorders.

19 Feb 2010

AGH neurosurgeons explore new therapeutic approach for brain tumor

Neurosurgeons at Allegheny General Hospital (AGH) are exploring use of a drug that illuminates brain tumor cells to determine if the experimental visualization technique will enhance their ability to surgically excise tumors and improve patient survival.

19 Feb 2010

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

VIRxSYS Corporation, a privately held company developing vaccines and RNA therapies for serious human diseases such as HIV and cardiovascular diseases, announced results from its prophylactic HIV vaccine (VRX1023) study in Rhesus Macaque monkeys during a presentation today at the 2010 Annual Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco, CA.

19 Feb 2010

Research shows natural compound in marine sponges reduces cancer cell motility

Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research) led by Kristiina Vuori, M.D., Ph.D., have discovered that the natural compound sceptrin, which is found in marine sponges, reduces cancer cell motility (movement) and has very low toxicity.

19 Feb 2010

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week in the online version of the Proceedings of the National Academy of Sciences.

19 Feb 2010

UCSF team: NIH ethics guidelines for embryonic stem cell research need to be modified

A UCSF team, led by bioethicist Bernard Lo, MD, recommends that the National Institutes of Health ethics guidelines for embryonic stem cell research be modified to better protect the rights of individuals donating egg or sperm to patients undergoing in vitro fertilization.

19 Feb 2010

Mechanosensitive ion channels play a key role in pain sensation

Humans and animals are able to perceive even the slightest vibration and touch of the skin. Mechanosensitive ion channels play a crucial role in the mediation of these sensations. Ion channels are pores in the cell membrane which are highly responsive to external signals.

19 Feb 2010

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Scientists at the Johns Hopkins Kimmel Cancer Center have used data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe can help physicians tailor patients' treatments. The genome-based blood tests, believed to be the first of their kind, may be used to monitor tumor levels after therapy and determine cancer recurrence.

19 Feb 2010

Cellular metabolism plays a key role in cancer development

It is not unusual to hear people blame their metabolism after gaining a few pounds. But changes in metabolism - the process that shapes how our bodies turn food into energy -- can have much more sinister effects than making it hard to fit into your favorite jeans.

19 Feb 2010

Unusual compounds in pitcher plant could prove effective against human fungal infections

The moment insects like flies, ants and beetles fall into a pitcher, the plant's enzymes are activated and begin dissolving their new meal, obtaining nutrients such as carbon and nitrogen which are difficult to extract from certain soils.

19 Feb 2010

Researchers find gene mutations that may provide clues for treating AML patients

Although leukemia is one of the best studied cancers, the cause of some types is still poorly understood. Now, a newly found mutation in acute myeloid leukemia patients could account for half of the remaining cases of adult acute leukemia with an unknown origin.

19 Feb 2010

Scottish scientists identify link between deprivation and breast cancer survival

Scottish scientists have shed light on the connection between deprivation and breast cancer survival, confirming that the link is mirrored at a genetic level.

19 Feb 2010

The Methodist Hospital Research Institute awarded $11.5M NIH grant for research into methods of targeting cancer stem cells

The Methodist Hospital Research Institute was awarded an $11.5 million Center Grant by the National Institutes for Health (NIH) today to study the best way to attack deadly cancer stem cells to enhance treatments for breast cancer. Other members of the team include Baylor College of Medicine and the University of Texas Health Science Center at Houston.

19 Feb 2010

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

Pathway Genomics™ (www.PATHWAY.com), a privately held, venture-backed company today announced that the Instituto de Referencia Andino (IRA), a Clinical Laboratory and Division of Rochem Biocare will offer Personal Genetic Health and Ancestry Testing to residents of Latin America.

18 Feb 2010

AGBT meeting: Study workshop on complete genome sequencing for human disease

Complete Genomics Inc., a third-generation human genome sequencing company, today announced that it will be unveiling some of its highly anticipated customer results at the 11th annual Advances in Genome Biology and Technology (AGBT) meeting to be held in Marco Island, Fla., Feb. 24-27, 2010.

18 Feb 2010

Single microRNA exhibits potential to forecast outcomes of MPM

Rosetta Genomics, Ltd., a leading developer and provider of microRNA-based molecular diagnostics, announced today that the results of a joint study with the NYU Langone Medical Center were published online on February 16th, 2010, and are set to be published in the March 1st issue of the American Association for Cancer Research’s journal, Cancer Research.

18 Feb 2010

BPA has no effects on brain development: New study

This new study, which exposed pregnant rodents to a range of BPA dietary doses from low to high, concluded that BPA had no effects on brain development or behavior in their offspring that had been exposed to BPA in utero and throughout development. The robust study was conducted by highly qualified researchers at WIL Research Laboratories.

18 Feb 2010

Norwegian government task force suggests formation of single company to commercialise biomaterial assets

Having studied the ethical, judicial and political arguments, the Norwegian government task force has suggested that a single nationwide company should be formed to commercialise biomaterials assets from the country’s various sources. The task force has also recommended HUNT Biosciences be a model for the national company.

18 Feb 2010

Medical Science News

Emerging concepts from gene regulation studies in immune cells

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Study shows how genes and environmental factors influence common human diseases

AGH neurosurgeons explore new therapeutic approach for brain tumor

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

Research shows natural compound in marine sponges reduces cancer cell motility

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

UCSF team: NIH ethics guidelines for embryonic stem cell research need to be modified

Mechanosensitive ion channels play a key role in pain sensation

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Cellular metabolism plays a key role in cancer development

Unusual compounds in pitcher plant could prove effective against human fungal infections

Researchers find gene mutations that may provide clues for treating AML patients

Scottish scientists identify link between deprivation and breast cancer survival

The Methodist Hospital Research Institute awarded $11.5M NIH grant for research into methods of targeting cancer stem cells

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

AGBT meeting: Study workshop on complete genome sequencing for human disease

Single microRNA exhibits potential to forecast outcomes of MPM

BPA has no effects on brain development: New study

Norwegian government task force suggests formation of single company to commercialise biomaterial assets

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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