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GIND scientists identify drug treatments that can normalize neuron development in AD

Scientists at the Gladstone Institute of Neurological Disease (GIND) have discovered that two main causes of AD amyloid-beta (Aβ) peptides and apolipoprotein E4 (apoE4) impair the growth of new neurons born in adult brains. What is more, they have identified drug treatments that can normalize the development of these cells even in the presence of Aβ or apoE4. The findings are described in two separate papers published in the current issue of Cell Stem Cell.

4 Dec 2009

TapeBeat.Com posts research on GeneLink

TapeBeat.Com the news and community portal for the serious investor has posted research on GeneLink (GNLK). GeneLink’s approach to well-being utilizes the science of pharmacogenenomics - using individual genetic variations to customize nutritional, skincare products and health maintenance products.

4 Dec 2009

Genetic differences determine intensity of people's responses to social rejection

Scientists have long known that opium-like painkillers, called opioids, relieve not only physical pain, but also some forms of emotional stress. Now, a new study reviewed by Faculty of 1000 Biology member Markus Heilig shows that small genetic differences in the gene for the opioid receptor can determine the intensity of people's responses to social rejection.

4 Dec 2009

Shorter amyloid fibres more toxic than longer counterparts, says study

A major discovery is challenging accepted thinking about amyloids - the fibrous protein deposits associated with diseases such as Alzheimer's and Parkinson's - and may open up a potential new area for therapeutics.

4 Dec 2009

Researchers discover new strategy against invasive parasite

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a possible strategy against an invasive parasite that infects more than a quarter of the world's population, including 50 million Americans.

4 Dec 2009

Combination of green tea and DAPH-12 chemicals may help prevent brain disorders

Scientists at Boston Biomedical Research Institute (BBRI) and the University of Pennsylvania have found that combining two chemicals, one of which is the green tea component EGCG, can prevent and destroy a variety of protein structures known as amyloids. Amyloids are the primary culprits in fatal brain disorders such as Alzheimer's, Huntington's, and Parkinson's diseases.

4 Dec 2009

New biochemical probe may help in identifying toxic proteins associated with Alzheimer's disease

Alzheimer's disease (AD) is one of the most heartbreaking diagnoses a person can receive. This irreversible, progressive brain disease slowly destroys memory and thinking skills and eventually even the ability to carry out the simplest tasks

4 Dec 2009

Discovery of antibiotic molecule may lead to the development of potent antibacterial drugs

An antibiotic that binds to a well-established target in a novel and unexpected way could be the inspiration for designing new, more potent antibacterial drugs.

4 Dec 2009

NIH approves new stem cell lines for research

The National Institutes of Health announced approval of embryonic stem cell lines for federally funded research. The Washington Post reports the decision is "opening the way for millions of taxpayer dollars to be used to conduct research that was put off-limits by President George W. Bush.

3 Dec 2009

Avisio forms new subsidiary to market its virus detecting nano sensory technology

Avisio, Inc. announced today that it has formed a majority-owned subsidiary to market and commercialize Instant Detect, the company's new nano sensory technology that instantly detects biological viruses. The new company, Diagnostic Nano Applications (DNA), will be headquartered in Riverside, California.

3 Dec 2009

IsoRay to distribute Oncura's I-125 brachytherapy seed

IsoRay, Inc. announced today that it has signed a distribution agreement with Oncura to distribute the I-125 brachytherapy seed, OncoSeed™.

3 Dec 2009

Aditi Technologies, Microsoft BioIT Alliance sign agreement on Bioinformatics program

Aditi Technologies, a leading provider of software product and application development services, today announced its strategic partnership with Microsoft BioIT Alliance to extend its services focus into Bioinformatics.

3 Dec 2009

Fruit flies are valid models for studying drug addiction in humans, says scientists

Fruit flies may seem like unlikely heroes in the battle against drug abuse, but new research suggests that these insects - already used to study dozens of human disease - could claim that role. Scientists are reporting that fruit flies can be used as a simpler and more convenient animal model for studying the effects of cocaine and other drugs of abuse on the brain.

3 Dec 2009

Body needs fasting periods to stay healthy

A body that is provided with food too often gets caught up in the maelstrom of a lack of exercise, obesity and ultimately diabetes. The trigger is a molecular switch that is controlled by insulin, a new study by scientists from ETH Zurich has revealed.

3 Dec 2009

Positive results from NanoBio's recombinant H5N1 flu antigen-nanoemulsion vaccine combination study

NanoBio Corporation today announced positive results from studies in mice in which immune responses were evaluated following administration of 5µg doses of recombinant H5N1 pandemic flu antigen combined with the company’s novel nanoemulsion vaccine. These studies are unique because the adjuvant was administered for the first time by subcutaneous (SC) and intramuscular (IM) injections.

3 Dec 2009

PEG polymer may prevent GI injury during cancer radiotherapy

A non-absorbed, oral co-polymer therapy under development by Midway Pharmaceuticals demonstrated the ability to protect against damage to healthy gastrointestinal tissues and to prevent lethal bacterial infections in animal models of radiation damage.

3 Dec 2009

TGen scientists win $1,000 prize for best scientific paper presented at BIBM09

A team of scientists at the Translational Genomics Research Institute (TGen) won a $1,000 prize for best scientific paper presented at BIBM09, a premier bioinformatics and biomedicine conference.

3 Dec 2009

Discovery of cell fibrous structure may provide clues to diagnose and treat medical disorders

Researchers from the Johns Hopkins Engineering in Oncology Center have shown that in healthy cells, a bundled "cap" of thread-like fibers holds the cell's nucleus, its genetic storehouse, in its proper place.

3 Dec 2009

Study: Stem cells from donor bone marrow may help repair heart damage

Adult stem cells may help repair heart tissue damaged by heart attack according to the findings of a new study to be published in the December 8 issue of the Journal of the American College of Cardiology. Results from the Phase I study show stem cells from donor bone marrow appear to help heart attack patients recover better by growing new blood vessels to bring more oxygen to the heart

3 Dec 2009

arGEN-X to develop its SIMPLE Antibody engine with completed EUR 12.5M Series A equity financing

arGEN-X BV, a biopharmaceutical company focused on the discovery and development of human antibodies using its proprietary SIMPLE Antibody(TM) platform, today announced the successful second closing of its Series A equity financing round. The Company raised an additional EUR 3.0 million (~USD 4.5 million) from two leading life science investors, Credit Agricole Private Equity and VIB (the prestigious Flemish research institute).

3 Dec 2009

Medical Science News

GIND scientists identify drug treatments that can normalize neuron development in AD

TapeBeat.Com posts research on GeneLink

Genetic differences determine intensity of people's responses to social rejection

Shorter amyloid fibres more toxic than longer counterparts, says study

Researchers discover new strategy against invasive parasite

Combination of green tea and DAPH-12 chemicals may help prevent brain disorders

New biochemical probe may help in identifying toxic proteins associated with Alzheimer's disease

Discovery of antibiotic molecule may lead to the development of potent antibacterial drugs

NIH approves new stem cell lines for research

Avisio forms new subsidiary to market its virus detecting nano sensory technology

IsoRay to distribute Oncura's I-125 brachytherapy seed

Aditi Technologies, Microsoft BioIT Alliance sign agreement on Bioinformatics program

Fruit flies are valid models for studying drug addiction in humans, says scientists

Body needs fasting periods to stay healthy

Positive results from NanoBio's recombinant H5N1 flu antigen-nanoemulsion vaccine combination study

PEG polymer may prevent GI injury during cancer radiotherapy

TGen scientists win $1,000 prize for best scientific paper presented at BIBM09

Discovery of cell fibrous structure may provide clues to diagnose and treat medical disorders

Study: Stem cells from donor bone marrow may help repair heart damage

arGEN-X to develop its SIMPLE Antibody engine with completed EUR 12.5M Series A equity financing

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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