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ImmunoCellular Therapeutics options immunotherapy targeting CSCs using abnormal Notch and Numb pathways

ImmunoCellular Therapeutics, Ltd., a biotechnology company that is focused on the development of novel immune-based cancer therapies, announced today that it has entered into an option agreement with The University of Texas M. D. Anderson Cancer Center relating to an immunotherapy targeting cancer stem cells (CSCs) which has demonstrated in pre-clinical animal models significant abilities to target and destroy CSCs.

3 Dec 2009

NHLBI awards new federal grant to improve the quality of stored transfusion blood

A new, $2.8 million, four-year federal grant will support researchers at the University of Pittsburgh School of Medicine and their collaborators at Wake Forest University as they study why the quality of stored transfusion blood degrades over time and how to address the problem.

3 Dec 2009

Khat Research Program: A new first-of-its-kind international research initiative

Mustafa al'Absi, Ph.D., professor of behavioral sciences at the University of Minnesota Medical School - Duluth Campus, and director of the Duluth Medical Research Institute, has received funding and launched a new first-of-its-kind international research initiative: "Khat Research Program: Neurobehavioral Impact of Long-Term Use".

3 Dec 2009

Research study compares genetic make-up of humans and primates

In spite of their genetic similarity to humans, chimpanzees and great apes have maximum lifespans that rarely exceed 50 years. The difference, explains USC Davis School of Gerontology Professor Caleb Finch, is that as humans evolved genes that enabled them to better adjust to levels of infection and inflammation and to the high cholesterol levels of their meat rich diets.

3 Dec 2009

VARI scientists determine the structure of receptors that plants use to sense ABA

Van Andel Research Institute (VARI) researchers have determined precisely how the plant hormone abscisic acid (ABA) works at the molecular level to help plants respond to environmental stresses such as drought and cold.

3 Dec 2009

New book presents latest research on neuroendocrine physiology

In this volume an international group of basic and clinical investigators presents their latest research on neuroendocrine physiology, advances in the control of the onset of puberty and its disorders, and basic and clinical aspects of the GH/IGF-1 and hypothalamic-pituitary-adrenal axes. An entire section is dedicated to pituitary tumors, including genetics and neuroimaging, and another covers the neuroendocrine control of substrate metabolism, including hypothalamic obesity and anorexia.

3 Dec 2009

Fitness levels linked to higher IQ in young adults

Young adults who are fit have a higher IQ and are more likely to go on to university, reveals a major new study carried out at the Sahlgrenska Academy and Sahlgrenska University Hospital.

3 Dec 2009

PanGenex capitalize on the immune-boosting properties of Spirulina

PanGenex Corporation, a global nutraceutical and dietary supplement manufacturer and marketer, announced today that the Company is actively identifying new product development opportunities that will initially focus on the immune-boosting properties of Spirulina.

3 Dec 2009

Novel approach to detect flaws in defense against breast cancer earns Era of Hope Scholar Award

A novel approach to detecting and targeting flaws in first line of defense against cancer has earned an Era of Hope Scholar Award from the U.S. Department of Defense for a scientist at The University of Texas M. D. Anderson Cancer Center.

2 Dec 2009

Fruit flies use same molecular mechanisms as humans for maintaining cholestrol

More importantly, according to two new studies led by a University of Utah human geneticist, fruit flies use the same molecular mechanisms as humans to help maintain proper balances of cholesterol and a key form of stored fat that contributes to obesity. The findings mean that as researchers try to learn more about the genetic and biological processes through which people regulate cholesterol and fat metabolism, the humble fruit fly, also called Drosophila, can teach humans much about themselves.

2 Dec 2009

Researchers discover ability of stem cells in brain cancer glioma to resist radiation therapy

Duke University Medical Center researchers have figured out how stem cells in the malignant brain cancer glioma may be better able to resist radiation therapy. And using a drug to block a particular signaling pathway in these cancer stem cells, they were able to kill many more glioma cells with radiation in a laboratory experiment.

2 Dec 2009

Adult stem cells may help repair heart tissue, reveals new study

Adult stem cells may help repair heart tissue damaged by heart attack according to the findings of a new study to be published in the December 8 issue of the Journal of the American College of Cardiology. Results from the Phase I study show stem cells from donor bone marrow appear to help heart attack patients recover better by growing new blood vessels to bring more oxygen to the heart.

2 Dec 2009

Study on the genetics of osteoarthritis

Interleukin Genetics, Inc. and NYU Langone Medical Center announced findings from a study performed in collaboration with Duke University on the genetics of osteoarthritis have been published this week in the "Online First" version of the Annals of Rheumatic Diseases and is available at http://ard.bmj.com/cgi/rapidpdf/ard.2009.113043v1.pdf.

2 Dec 2009

Vitro Diagnostics files a patent application for its technology related to generation of iPS cells

Vitro Diagnostics, Inc., dba Vitro Biopharma, announced the filing of a new United States patent application entitled “POU5-F1 Expression in Human Mesenchymal Stem Cells” and the development of new technology related to generation of human induced pluripotent stem cells (iPS).

2 Dec 2009

University of Pittsburgh's McGowan Institute for Regenerative Medicine awarded IBM SUR grant

The University of Pittsburgh's McGowan Institute for Regenerative Medicine, which connects scientists who work on tissue engineering, cell therapies, artificial organs and biodevices, has been awarded a Shared University Research (SUR) Award from IBM ( IBM). The IBM SUR Award will provide IBM computer hardware, software and services to Pitt for its cutting-edge "in silico" biological research, which uses computer simulations to explore biological pathways and test therapeutic interventions.

2 Dec 2009

Patient enrollment complete in Peregrine Pharmaceuticals' Cotara trial

Peregrine Pharmaceuticals, Inc. today reported completion of patient enrollment in a dose confirmation and dosimetry trial of Cotara® in patients with relapsed glioblastoma multiforme (GBM), the deadliest form of brain cancer. Cotara is a targeted monoclonal antibody linked to a radioisotope being developed as a potential new treatment for GBM.

2 Dec 2009

World’s first 1000 MHz ultra-high field NMR AVANCE spectrometer installed at CRMN, France

Bruker BioSpin has successfully completed the installation of the world’s first 1000 MHz ultra-high field NMR AVANCE™ spectrometer at the Centre de Resonance Magnétique Nucléaire à Très Hauts Champs (CRMN) in Lyon, France (a joint research unit of CNRS, Ecole Normale Supérieure de Lyon and Université Lyon 1).

2 Dec 2009

Medical Science News

ImmunoCellular Therapeutics options immunotherapy targeting CSCs using abnormal Notch and Numb pathways

NHLBI awards new federal grant to improve the quality of stored transfusion blood

Khat Research Program: A new first-of-its-kind international research initiative

Research study compares genetic make-up of humans and primates

VARI scientists determine the structure of receptors that plants use to sense ABA

New book presents latest research on neuroendocrine physiology

Fitness levels linked to higher IQ in young adults

PanGenex capitalize on the immune-boosting properties of Spirulina

Novel approach to detect flaws in defense against breast cancer earns Era of Hope Scholar Award

Fruit flies use same molecular mechanisms as humans for maintaining cholestrol

Researchers discover ability of stem cells in brain cancer glioma to resist radiation therapy

Adult stem cells may help repair heart tissue, reveals new study

Study on the genetics of osteoarthritis

Vitro Diagnostics files a patent application for its technology related to generation of iPS cells

University of Pittsburgh's McGowan Institute for Regenerative Medicine awarded IBM SUR grant

Patient enrollment complete in Peregrine Pharmaceuticals' Cotara trial

World’s first 1000 MHz ultra-high field NMR AVANCE spectrometer installed at CRMN, France

S*BIO to present data on its novel oral JAK2 inhibitor at The American Society of Hematology meeting

Protein marker may hold the key against pancreatic cancer

Pycnogenol can improve microcirculation, retinal edema and visual acuity, reveals study

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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