Molecular & Structural Biology

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Purdue researchers develop new way to view and classify protein 3D shapes

Proteins can provide a detailed look inside the human body and how it protects itself from many diseases. Proteins, which make up about 15% of body mass, are the most abundant solid substances in the human body.

9 May 2019

New research defines the chain of molecular events that goes awry in sepsis

Sepsis is a medical condition that few patients have heard of and most doctors dread. The body's response to attack by bacteria can trigger a cascade of cellular self-destruction that inadvertently causes blood clots, multi-organ failure, and death.

8 May 2019

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasize is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.

8 May 2019

Cell's cytoskeleton aids in energy transfer and information processing within neurons, study finds

Dysfunctions and malformations in the scaffold of a cell are thought to contribute to heart muscle weakness, neurodegenerative disease and even deafness.

8 May 2019

Biophysicists study structure of KR2 rhodopsin under physiological conditions

A team of biophysicists from Russia, Germany, and France, featuring researchers from the Moscow Institute of Physics and Technology, has discovered and studied the structure of the KR2 rhodopsin under physiological conditions.

8 May 2019

Cornell scientists discover new 'jumping' superbug gene

While sifting through the bacterial genome of salmonella, Cornell University food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world's few last-resort antibiotics.

7 May 2019

Scientific research articles show that imipridones target mitochondrial function in cancer cells

Oncoceutics, Inc. announced the publication of two scientific research articles demonstrating that members of the imipridone family ONC201 and ONC212 directly activate a mitochondrial protease called caseinolytic protease P.

7 May 2019

Unexpected role of junk RNA in cancer opens new way for treatment of the disease

In an article just published by Trends in Cancer online, Dr. Alan Herbert, founder at InsideOutBio, highlights how the way cancer cells solve the problem of junk RNA makes them vulnerable to a new type of cancer therapy.

7 May 2019

Researchers develop new molecule that binds to the cerebrovascular system

Brazilian and US researchers have developed a molecule called FRW that, in tests with mice, proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream.

7 May 2019

Novel bioinformatics tool improves gene identification

Like finding a needle in a haystack, identifying genes that are involved in particular diseases can be an arduous and time consuming process.

6 May 2019

Form drives function in cancer proliferation, UTSW study finds

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

6 May 2019

New dataset will help researchers better understand how the brain processes images

Neuroscientists and computer vision scientists say a new dataset of unprecedented size -- comprising brain scans of four volunteers who each viewed 5,000 images -- will help researchers better understand how the brain processes images.

6 May 2019

MIT researchers develop novel method for analyzing massive cell datasets

Data-sampling method makes "sketches" of unwieldy biological datasets while still capturing the full diversity of cell types.

3 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Cornell University study uncovers relationship between starch digestion gene and gut bacteria

A newly discovered relationship between genetic variation and the gut microbiome could help nutritionists personalize their recommendations.

2 May 2019

New research uncovers how superbug evades the immune system to cause infection

New research led by the University of Sheffield has discovered how a hospital superbug evades the immune system to cause infection - paving the way for new treatments.

30 Apr 2019

Will gene-editing of human embryos ever be justifiable?

World-leading medical ethicist Professor Arthur Caplan has published a series of recommendations with the aim of addressing worldwide concerns over gene editing of human embryos.

30 Apr 2019

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

In the majority of cases, dementia can be traced back to Alzheimer's disease. Its causes are not really understood yet. What is known is that plaques form from misfolded proteins and that there is an increase in neuronal cell death levels in the brain. However, the plaques don't necessarily go hand in hand with any symptoms.

30 Apr 2019

Parasitoid wasps zombify spiders by hacking web-spinning mechanisms

Setting off a startling chain of events, a parasitoid wasp can force a spider to weave a special web to suspend the wasp pupa just before it finishes killing its spider host.

30 Apr 2019

Molecular & Structural Biology

Purdue researchers develop new way to view and classify protein 3D shapes

New research defines the chain of molecular events that goes awry in sepsis

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Cell's cytoskeleton aids in energy transfer and information processing within neurons, study finds

Biophysicists study structure of KR2 rhodopsin under physiological conditions

Cornell scientists discover new 'jumping' superbug gene

Scientific research articles show that imipridones target mitochondrial function in cancer cells

Unexpected role of junk RNA in cancer opens new way for treatment of the disease

Researchers develop new molecule that binds to the cerebrovascular system

Novel bioinformatics tool improves gene identification

Form drives function in cancer proliferation, UTSW study finds

New dataset will help researchers better understand how the brain processes images

MIT researchers develop novel method for analyzing massive cell datasets

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

Scientists describe how cells 'decide' between pluripotency and differentiation

Cornell University study uncovers relationship between starch digestion gene and gut bacteria

New research uncovers how superbug evades the immune system to cause infection

Will gene-editing of human embryos ever be justifiable?

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

Parasitoid wasps zombify spiders by hacking web-spinning mechanisms

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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