Molecular & Structural Biology

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Super-Resolution Raman Imaging with Plasmonic Substrates

Renee Frontiera discusses the development of a super-resolution Raman microscope that could one day supersede fluorescence-based super-resolution microscopes.

From Pittcon 14 Jun 2019

Polycomb protein EED plays a complex role in brain development

The dentate gyrus (DG) is the input region of the hippocampus and plays an important role in learning and memory.

13 Jun 2019

Norovirus structures could help develop therapeutics to fight food-borne illness

Noroviruses are a leading cause of food-borne illness outbreaks, accounting for 58% of all outbreaks and cause 685 million cases worldwide each year. There is no effective therapeutic against them. Having knowledge of the intricate structure of the outer layer of noroviruses, the capsid, which allows the virus to attach to its human host, could help in vaccine development.

13 Jun 2019

Researchers develop first blood-brain barrier chip using stem cells

Researchers at Ben-Gurion University of the Negev and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier, creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.

13 Jun 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Complex molecular conversation is key to the establishment of 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

11 Jun 2019

Bruker launches timsTOF fleX with ESI/MALDI capability for SpatialOMx at ASMS 2019

Bruker Daltonics has launched a novel timsTOF fleX mass spectrometer which combines ESI/MALDI capability for SpatialOMx on a single instrument.

From Bruker Life Sciences Mass Spectrometry 10 Jun 2019

Human body is a mosaic pattern of DNA mutations, say researchers

Researchers have discovered that the cells of the human body aren’t clones of a single DNA sequence, but are actually a mosaic of mutations.

7 Jun 2019

Longevity-related molecular programs do not last beyond midlife

Just as a computer requires code to work, our bodies are regulated by molecular "programs" that are written early in life and then have to do their job properly for a lifetime. But do they? It's a question that has intrigued researchers for years.

7 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Telomere shortening in adulthood is not caused by smoking, say researchers

A new study suggests that telomere length in adults should be regarded as a static biomarker that does not significantly change during adult life.

7 Jun 2019

Scientists develop faster, easier method for making amino acid chains

Scientists often build new protein molecules by stringing groups of amino acids together. These amino acid chains, called polypeptides, are the building blocks needed in drug development and the creation of new biomaterials.

7 Jun 2019

Study: Smoking does not shorten the length of telomeres

A new study has surprised the medical world, finding that smoking does not shorten the length of telomeres - a marker at the end of our chromosomes that is widely accepted as an indicator of aging.

6 Jun 2019

A novel approach to intraplaque mast cell characterization in atherosclerosis

Researchers have devised a new flow-cytometric method to identify a subpopulation of intraplaque mast cells, the primary immune mediators of atherosclerosis.

6 Jun 2019

Scientists successfully carry out gene editing in vivo

Scientists at Harvard University have successfully proven that stem cells can be edited inside the body, rather than in a petri dish.

5 Jun 2019

Researchers investigate how antibiotic produced by the microbiome kills bacteria

A research team from the Universities of Tübingen and Göttingen as well as from the German Center for Infection Research has investigated the mode of action of a new class of antibiotics that is highly effective against multidrug-resistant pathogens.

4 Jun 2019

Scientists 'on the right track' toward universal flu vaccine

New research could bring scientists a step closer to developing an effective, universal flu vaccine.

4 Jun 2019

Study uncovers pigment cells that change their identity during normal development

A new study by researchers at the University of Virginia and other institutions has discovered a type of pigment cell in zebrafish that can transform after development into another cell type.

4 Jun 2019

Snapshot of chikungunya could help find new ways to prevent or treat viral arthritis

Chikungunya virus, once confined to the Eastern Hemisphere, has infected more than 1 million people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

4 Jun 2019

Study identifies promising cancer target for liposarcoma

A study conducted by a team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed a close association between liposarcoma (LPS), a type of cancer that develops from fat cells, and the bromodomain and extraterminal (BET) protein family.

3 Jun 2019