Molecular & Structural Biology

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Rat study gives a glimpse into habitat of 'Hobbit' hominin

A study of rat body sizes shifting over time gives a glimpse into the habitat of the mysterious hominin Homo floresiensis -- nicknamed the "Hobbit" due to its diminutive stature.

14 Mar 2019

Researchers define pathway that helps us make antibodies

Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.

13 Mar 2019

Brain pathway supporting intersection of taste and pain identified

University of Oklahoma neuroscientists have found a pathway in the brain where taste and pain intersect in a new study that originally was designed to look at the intersection of taste and food temperature.

13 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

UNH study finds how gender-biased protein may play role in autism

Researchers at the University of New Hampshire are one step closer to helping answer the question of why autism is four times more common in boys than in girls after identifying and characterizing the connection of certain proteins in the brain to autism spectrum disorders.

12 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Proving the efficacy of traditional Chinese medicine

Using GC-MS, scientists have uncovered the anti-pyretic mechanisms of Jinxin, a traditional Chinese medicine typically prescribed for fever.

11 Mar 2019

Blood donors' leftover immune cells provide crucial insights into antibody affinity

During some kinds of blood donations, you get most of your blood back. For example, platelet donation involves a procedure in which donor blood is filtered to harvest the platelets for medical use and the rest of the blood components are returned to the donor's body.

11 Mar 2019

Creating increasingly complex brain organoids

Scientists improved the initial steps of a standard protocol and produced organoids displaying regionalized brain structures, including retinal pigmented cells. The announcement was published today in BMC Developmental Biology by the D'Or Institute for Research and Education's team.

8 Mar 2019

CAR-T cell therapy could be on the horizon for patients with lupus

Researchers have developed a novel CAR-T cell therapy that can reduce B cell numbers known to cause the inflammatory responses in lupus.

7 Mar 2019

Genetic manipulation can double life expectancy and increase health of offspring

By manipulating the genes that make humans age, researchers have discovered that lifespans can be doubled with a better quality of life for offspring.

6 Mar 2019

Researchers discover facile method for introduction of fluorine atoms into organic molecules

The vast majority of pharmaceuticals employed in the treatment of human diseases are of an organic nature, meaning that the active component is a molecule (or a combination of several molecules) that is constituted of carbon and hydrogen atoms.

6 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

New approach to creating 'theranostics' for targeting specific tumors, diseases

A City of Hope scientist and his colleagues have developed a user-friendly approach to creating "theranostics" - therapy combined with diagnostics - that target specific tumors and diseases.

6 Mar 2019

Study sheds new light on early development of embryos

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.

5 Mar 2019