Molecular & Structural Biology

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Different levels of two molecules from same family can influence prognosis of liposarcoma

Researchers at Hiroshima University have found that different levels of two molecules of the same family--TIMP-1 and TIMP-4--can influence prognosis of liposarcoma.

14 May 2019

Brazilian researchers develop new strategy to starve triple negative breast cancer cells

A team of Brazilian researchers has developed a strategy that slows the growth of triple negative breast cancer cells by cutting them off from two major food sources.

13 May 2019

Research on repetitive worm behavior may shed light on repetition in humans

Repetition can be useful if you're trying to memorize a poem, master a guitar riff, or just cultivate good habits.

13 May 2019

Nanotubes enable movement of toxic protein linked to Huntington's disease

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

11 May 2019

Study reveals how dengue virus replicates in infected cells

The nonstructural protein 1 of the dengue virus interacts with another viral protein called NS4A-2K-4B to enable viral replication, according to a study published May 9 in the open-access journal PLOS Pathogens by Ralf Bartenschlager of the University of Heidelberg, and colleagues.

10 May 2019

Egg yolk precursor protein plays key role in regulating mosquitos’ attraction to humans

Feeding mosquitoes sugar makes them less attracted to humans, a response that is regulated by the protein vitellogenin, according to a study publishing May 9 in the open-access journal PLOS Biology by Jessica Dittmer, Paolo Gabrieli and colleagues at the Università degli Studi di Pavia in Italy.

10 May 2019

New computational framework reveals impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice.

10 May 2019

AMP offers recommendations to aid in design and validation of clinical CYP2C9 assays

The Association for Molecular Pathology, the premier global, molecular diagnostic professional society, today published consensus, evidence-based recommendations to aid in the design and validation of clinical CYP2C9 assays, promote standardization of testing across different laboratories and improve patient care.

10 May 2019

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Most antibiotics work by interfering with critical functions such as DNA replication or construction of the bacterial cell wall.

10 May 2019

Scientists successfully create melanocyte precursor cells using stem cell technology

Our hair, skin and eyes are colored by a pigment called melanin, which is produced by pigment cells called melanocytes. Scientists have used stem cell technology to successfully create melanocyte precursor cells.

10 May 2019

Purdue researchers develop new way to view and classify protein 3D shapes

Proteins can provide a detailed look inside the human body and how it protects itself from many diseases. Proteins, which make up about 15% of body mass, are the most abundant solid substances in the human body.

9 May 2019

New research defines the chain of molecular events that goes awry in sepsis

Sepsis is a medical condition that few patients have heard of and most doctors dread. The body's response to attack by bacteria can trigger a cascade of cellular self-destruction that inadvertently causes blood clots, multi-organ failure, and death.

8 May 2019

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasize is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.

8 May 2019

Molecular & Structural Biology

Different levels of two molecules from same family can influence prognosis of liposarcoma

Brazilian researchers develop new strategy to starve triple negative breast cancer cells

Research on repetitive worm behavior may shed light on repetition in humans

Nanotubes enable movement of toxic protein linked to Huntington's disease

Study reveals how dengue virus replicates in infected cells

Egg yolk precursor protein plays key role in regulating mosquitos’ attraction to humans

New computational framework reveals impact of arthritis drugs on gene expression

AMP offers recommendations to aid in design and validation of clinical CYP2C9 assays

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Scientists successfully create melanocyte precursor cells using stem cell technology

Purdue researchers develop new way to view and classify protein 3D shapes

New research defines the chain of molecular events that goes awry in sepsis

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Cell's cytoskeleton aids in energy transfer and information processing within neurons, study finds

Biophysicists study structure of KR2 rhodopsin under physiological conditions

Cornell scientists discover new 'jumping' superbug gene

Scientific research articles show that imipridones target mitochondrial function in cancer cells

Unexpected role of junk RNA in cancer opens new way for treatment of the disease

Researchers develop new molecule that binds to the cerebrovascular system

Novel bioinformatics tool improves gene identification

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