Molecular & Structural Biology

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Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

Researchers have long thought that once a cell starts down its path of differentiation, growing into a skin cell or a liver cell or a neuron, that path could not be changed.

7 Jun 2023

Chain reaction: Nutritional keys to a healthier diet may lie in unraveling starch structures

The chain length distribution (CLD) of starch plays a crucial role in human health, affecting the digestibility of starch-containing foods and correlating with diseases like diabetes, cardiovascular disease, and obesity. By understanding and manipulating CLDs, it is possible to develop plant varieties that provide improved health properties in starch-based foods.

6 Jun 2023

World's fastest camera can detect fluorescence from single molecules

Researchers at Kyoto University, Okinawa Institute of Science and Technology Graduate University (OIST), and Photron Limited in Japan have developed the world's fastest camera capable of detecting fluorescence from single molecules.

6 Jun 2023

Efficient machine learning pipeline predicts the location of nanoscale interactions

Identifying whether and how a nanoparticle and protein will bind with one another is an important step toward being able to design antibiotics and antivirals on demand, and a computer model developed at the University of Michigan can do it.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Study provides a treasure trove of information on molecular biology of the immune system

Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system to help treat autoimmune diseases.

5 Jun 2023

Groundbreaking study maps molecular architecture of the visual system's integral components

A groundbreaking study has taken a significant step towards understanding the complexities of the human eye.

4 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

How does a riboswitch regulate its own synthesis?

To prevent a global health crisis, scientists around the world are searching for ways to fight bacteria that can evade the current arsenal of antibiotics.

2 Jun 2023

Experts find remnants of ancient RNA viruses embedded inside reef-building corals

An international team of marine biologists has discovered the remnants of ancient RNA viruses embedded in the DNA of symbiotic organisms living inside reef-building corals.

2 Jun 2023

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

1 Jun 2023

Groundbreaking 3D imaging unveils secrets of cilia

Study provides a comprehensive analysis of human primary cilia, uncovering their architectural features and functional implications in cellular processes. It highlights the importance of these sensory organelles in signaling, motility, and intercellular communication.

31 May 2023

New method to study the ultra-fast movements of proteins

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

30 May 2023

Fast and accurate automatic neuron reconstruction using 3D images

Dr. Shuiwang Ji, a professor in the Department of Computer Science and Engineering at Texas A&M University, is part of a collaborative research community that recently had its paper titled "BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets" published in the April issue of the journal Nature Methods.

26 May 2023

Immune cells targeting core protein play an important role in early immune defense against COVID-19

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

For pharmaceuticals, knowing the chemical composition is not enough - molecular geometry and crystal structure also play an important role in a drug's activity.

23 May 2023

Molecular & Structural Biology

Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

Chain reaction: Nutritional keys to a healthier diet may lie in unraveling starch structures

World's fastest camera can detect fluorescence from single molecules

Efficient machine learning pipeline predicts the location of nanoscale interactions

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Study provides a treasure trove of information on molecular biology of the immune system

Groundbreaking study maps molecular architecture of the visual system's integral components

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

How does a riboswitch regulate its own synthesis?

Experts find remnants of ancient RNA viruses embedded inside reef-building corals

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Peptidomimetic antibiotics may be effective against resistant bacteria

Study sheds light on metabolic enzymes and processes essential for DNA damage repair

Groundbreaking 3D imaging unveils secrets of cilia

New method to study the ultra-fast movements of proteins

Fast and accurate automatic neuron reconstruction using 3D images

Immune cells targeting core protein play an important role in early immune defense against COVID-19

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Scientists study the structure and function of a transporter involved in cancer, immunity

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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