Molecular & Structural Biology

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Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer.

16 Nov 2022

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath in the UK.

16 Nov 2022

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

15 Nov 2022

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed.

15 Nov 2022

Unique peptides with anti-cancer potential discovered

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

14 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Neuromedin U decreases food intake and raises energy expenditure in mice, not in rats

Our sensory urges ranging from anger to hunger are regulated by hormonal or neuronal signals. Often, these impulses appear as behavioral responses, evoked through complex biological reactions.

11 Nov 2022

Study shows the importance of preserving microglia and Sirt1 functional efficiency for longevity

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 20, entitled, "Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns."

11 Nov 2022

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.

10 Nov 2022

MicroRNAs can upregulate proteins in addition to downregulating protein production

microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such as tumor cells.

10 Nov 2022

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes.

10 Nov 2022

Researchers characterize subtle differences in the brains of primates and humans

While the physical differences between humans and non-human primates are quite distinct, a new study reveals their brains may be remarkably similar. And yet, the smallest changes may make big differences in developmental and psychiatric disorders.

9 Nov 2022

Scientists create an atlas of liver infection caused by Plasmodium parasites

Malaria is a devastating disease caused by the Plasmodium parasite. After an infected mosquitos' bite, the parasites travel to the liver and infect liver cells.

9 Nov 2022

Protein complex may present strong therapeutic target for lethal breast cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that a protein complex that governs gene expression (called CoREST) sometimes gets rewired during breast cancer to help estrogen receptor positive (ER+) tumors resist endocrine therapies and become more aggressive.

8 Nov 2022

Molecular & Structural Biology

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

Unique peptides with anti-cancer potential discovered

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Neuromedin U decreases food intake and raises energy expenditure in mice, not in rats

Study shows the importance of preserving microglia and Sirt1 functional efficiency for longevity

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

MicroRNAs can upregulate proteins in addition to downregulating protein production

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Researchers characterize subtle differences in the brains of primates and humans

Scientists create an atlas of liver infection caused by Plasmodium parasites

Protein complex may present strong therapeutic target for lethal breast cancer

Study uncovers a previously unknown propofol effect in neurons

Study sheds light on how Gram-negative bacteria construct outer membrane to resemble body armor

New insights into the dynamic inner world of the human immune system

Vimentin is an important co-receptor for SARS-CoV-2 infection

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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