Molecular & Structural Biology

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New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

A new study focuses on understanding the factors associated with the ability of the Omicron variant to infect a wide range of age groups.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Structure of protein that can pump toxic molecules out of bacterial cells revealed

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

18 Feb 2022

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

18 Feb 2022

Study hints a potential difference in molecular clockworks between the master and slave clock neurons

From tiny fruit flies to human beings, all animals on Earth maintain their daily rhythms based on their internal circadian clock.

17 Feb 2022

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

When most people think of flavonoids, natural compounds found in plants and other organisms, their nutritional benefits probably come to mind first.

17 Feb 2022

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Researchers discover a novel group of proteins that exists in all domains of life

Proteins are the "workhorses" in every living cell and constitute the chemical basis of life. These little machines are required to turn food into energy, to manage motion and brain activities and to fight off bacteria and viruses.

17 Feb 2022

Researchers discover a new and unconventional nuclear function for cancer microRNA

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Zebrafish model reveals how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Precise communication of two key memory regions boosts formation of lasting memories

In a new, rare study of direct brain recordings in children and adolescents, a Northwestern Medicine scientist and colleagues from Wayne State University have discovered as brains mature, the precise ways by which two key memory regions in the brain communicate make us better at forming lasting memories.

15 Feb 2022

Molecular & Structural Biology

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Scientists use entire human GI tracts to shed light on cellular functions

Researchers unravel essential final steps in the production of mRNA

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

The impact of SARS-CoV-2 on lipids

Structure of protein that can pump toxic molecules out of bacterial cells revealed

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

Study hints a potential difference in molecular clockworks between the master and slave clock neurons

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Research shows alterations in transfer RNAs at the epigenetic level in cancer

New research shines light on mysterious dynamics that define the interplay between nerves and muscle

Researchers discover a novel group of proteins that exists in all domains of life

Researchers discover a new and unconventional nuclear function for cancer microRNA

Zebrafish model reveals how early embryo cells begin to independently produce proteins

Precise communication of two key memory regions boosts formation of lasting memories

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Prediction of SARS-CoV-2 epitope candidates for future vaccines

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

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