Molecular & Structural Biology

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Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Researchers develop a new tool to help provide early warning of rare and unknown viruses

Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses.

15 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

Research provides fundamental insight into motor planning under uncertainty

In baseball, a pitch can take as little as 400 milliseconds to reach the plate. With a typical reaction time of 200 milliseconds and a swing of about 150 milliseconds, a batter must decide whether to swing and how to swing based only on the first 10 to 20 percent of the ball's flight.

15 Sep 2021

A family of proteins may be able to outwit emerging and re-emerging viruses

A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.

15 Sep 2021

A protein found to be effective at reversing aging in skeletal muscle cells

A University at Buffalo-led research team has shown that a protein named for the mythical land of youth in Irish folklore is effective at reversing aging in skeletal muscle cells.

15 Sep 2021

New slow-release system mimics nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties.

14 Sep 2021

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

Progress on treating Alzheimer's disease has been frustratingly slow. A group of scientists in Houston suggest frustration at a very small scale may lead to a new path toward treatment.

14 Sep 2021

New method for profiling tissue-specific secretory proteins in live mice

Researchers have presented a method for profiling tissue-specific secretory proteins in live mice. This method is expected to be applicable to various tissues or disease models for investigating biomarkers or therapeutic targets involved in disease progression.

14 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Study compares DNA extraction and amplification methods used for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

14 Sep 2021

RIT study uncovers new information about how coronavirus attaches itself to human cells

Rochester Institute of Technology scientists have uncovered new information about the way coronavirus and several of its variants attach to human cells.

13 Sep 2021

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer's and Parkinson's.

13 Sep 2021

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

12 Sep 2021

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

A research team from the Universitat Autònoma de Barcelona has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio A disease.

12 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine.

8 Sep 2021

Research uses rodent models to connect the influence of feronomic signals on memory

The work, published recently in Nature Communications, used a model of rodents and managed to connect for the first time the influence of feronomic signals on memory. This will make it possible to explore the deficits of integration of spatial memories and social studies in transgenic models of Alzheimer's disease in the future.

7 Sep 2021

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

As part of its "Life?" project, the Volkswagen Foundation is funding a research project that is placing membraneless organelles within cells in the spotlight as a way of understanding the fundamental processes that are essential to life.

6 Sep 2021

New insights could help unlock the mystery of how lung cancer arises in never smokers

A genomic analysis of lung cancer in people with no history of smoking has found that a majority of these tumors arise from the accumulation of mutations caused by natural processes in the body.

6 Sep 2021

Molecular & Structural Biology

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers develop a new tool to help provide early warning of rare and unknown viruses

Analysis of the immune landscape in mild-to-moderate COVID-19

Research provides fundamental insight into motor planning under uncertainty

A family of proteins may be able to outwit emerging and re-emerging viruses

A protein found to be effective at reversing aging in skeletal muscle cells

New slow-release system mimics nature to provide long-lasting local anesthesia

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

New method for profiling tissue-specific secretory proteins in live mice

GIST researchers unravel coordination mechanism of base excision repair

Study compares DNA extraction and amplification methods used for microbiome research

RIT study uncovers new information about how coronavirus attaches itself to human cells

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

NIH researchers develop a detailed cellular map of chronic MS lesions

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

Research uses rodent models to connect the influence of feronomic signals on memory

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

New insights could help unlock the mystery of how lung cancer arises in never smokers

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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