Molecular & Structural Biology

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Glycerin helps calm the red itchy patches in psoriasis model

Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis and now scientists have objective evidence to support their reports.

4 Oct 2021

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases.

4 Oct 2021

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

A recent study discusses the rate of changes in peripheral blood white cells in individuals who have recovered from SARS-CoV-2 infection.

3 Oct 2021

Researchers use unnatural amino acids to create fluorescent proteins for studying biological systems

Proteins are the molecular machines that make all living things hum. They stop deadly infections, heal cells, capture energy from the sun and so much more.

2 Oct 2021

Protein network map uncovers previously unknown cancer drivers

In three studies from the Cancer Cell Map Initiative, researchers uncovered previously unknown interactions between proteins that drive cancer and combined this new data to generate a map of protein pathways informing cancer outcomes.

30 Sep 2021

Research points the way to identifying new precision treatments for cancer

Researchers at University of California San Diego and University of California San Francisco have mapped out how hundreds of mutations involved in two types of cancer affect the activity of discrete groups of proteins that are the ultimate actors behind the disease.

30 Sep 2021

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Gyros Protein Technologies AB today announced the introduction of Gyrolab® AAV9 Titer Kit for rapid determination of titer in AAV9 vector-based cell and gene therapy manufacturing.

From Gyros Protein Technologies AB 30 Sep 2021

Hippocampus connects separate, distant events to form narrative memories, study shows

People love stories. We find it easier to remember events when they are part of an overarching narrative. But in real life, the chapters of a story don't follow smoothly one from another. Other things happen in between.

30 Sep 2021

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

One of modern biologists' most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms.

30 Sep 2021

New system synthetically reconnects neural circuits using neuropeptides from Hydra

For two people to communicate in a loud, crowded room, they need to be standing side by side. The same is often true for neurons in the brain. But the same way a cell phone allows two people to communicate clearly across the room, new research at the Marine Biological Laboratory (MBL) opened up a new channel of communication in the worm C. elegans brain.

30 Sep 2021

Yale researchers uncover how the brain takes shape during mid-pregnancy

About four or five months after conception, a burst of synaptic growth begins in the prefrontal cortex (PFC) of the human fetus.

29 Sep 2021

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known as "epitranscriptomics." These base modifications can occur to most types of RNA molecules, including microRNAs.

29 Sep 2021

Two proteins joined together using a free-standing, rigid link

Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights.

29 Sep 2021

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is a protein that tends to accumulate in increasing amounts, and the amount is strictly controlled by the splicing of TDP-43. Through cell experiments and analysis of human brain tissue, researchers at Brain Research Institute, Niigata University, led by Akihiro Sugai, M.D., Ph.D., have found that methylation of TDP-43 DNA is involved in the background of motor cortex involvement with aging in ALS

29 Sep 2021

New findings highlight the need to expand the toolbox to fight against COVID-19

When Kamlendra Singh flew back to Missouri from India in April, he developed a cough and fever on the plane, despite being vaccinated for COVID-19 and testing negative for the virus right before departure.

28 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Research reveals nucleolar RNA interference based on C. elegans as a model organism

A research group led by Prof. GUANG Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. FENG Xuezhu from the First Affiliated Hospital of USTC, revealed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism. The study was published in Nuclear Acids Research.

28 Sep 2021

Researchers discover working mechanism of potential drug targets for COVID-19

A team of international researchers, including McGill Professor Stéphane Laporte, have discovered the working mechanism of potential drug targets for various diseases such as cancer, rheumatoid arthritis, and even COVID-19.

28 Sep 2021

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

Molecular & Structural Biology

Glycerin helps calm the red itchy patches in psoriasis model

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

Researchers use unnatural amino acids to create fluorescent proteins for studying biological systems

Protein network map uncovers previously unknown cancer drivers

Research points the way to identifying new precision treatments for cancer

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Hippocampus connects separate, distant events to form narrative memories, study shows

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

New system synthetically reconnects neural circuits using neuropeptides from Hydra

Yale researchers uncover how the brain takes shape during mid-pregnancy

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

Two proteins joined together using a free-standing, rigid link

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

New findings highlight the need to expand the toolbox to fight against COVID-19

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

Research reveals nucleolar RNA interference based on C. elegans as a model organism

Researchers discover working mechanism of potential drug targets for COVID-19

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

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