Molecular & Structural Biology

RSS

Scientists identify new therapeutic target for several aggressive cancers

A protein in tumor cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown.

4 Aug 2021

Key protein linked to both physical fitness in youth and diseases of old age

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

4 Aug 2021

Research shows how neurons learn to pick the most energy-efficient perturbations

Brains have evolved to do more with less. Take a tiny insect brain, which has less than a million neurons but shows a diversity of behaviors and is more energy- efficient than current AI systems.

3 Aug 2021

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Treating mice that have a Parkinson's disease-causing mutation with a small molecule compound restores the removal of damaged mitochondria from their brain cells, shows a study published today in eLife.

3 Aug 2021

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry.

3 Aug 2021

Experimental model shows how topological defects in the mesothelium affect ovarian cancer metastasis

Ovarian cancer devastates more than 20,000 women in the U.S. every year, due in part to its tendency to evade detection and present after metastatic spread. A key element to slowing metastasis is understanding the mechanisms of how tumor cells invade tissues.

3 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight -; not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today in Science Advances.

30 Jul 2021

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs.

30 Jul 2021

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Mitofusin 2 is a key protein in the regulation of the physiology of mitochondria ─cellular organelles that produce energy─ involved in several neurodegenerative and cardiovascular diseases, as well as in cancer.

30 Jul 2021

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors.

29 Jul 2021

Mini-antibodies efficiently block SARS-CoV-2 virus

Göttingen researchers have developed mini-antibodies that efficiently block the coronavirus SARS-CoV-2 and its dangerous new variants.

28 Jul 2021

Researchers create detailed molecular atlas of fetal development of the brain

Researchers at Karolinska Institutet in Sweden have developed a detailed molecular atlas of the fetal development of the brain.

28 Jul 2021

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Oncotarget published "TERT and its binding protein: overexpression of GABPA/B in high grade gliomas" which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas.

28 Jul 2021

Research provides insights into how the hippocampus contributes to memory storage in the cortex

A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored in the visual cortex, the ability to recognize a sequence of sights critically depends on guidance from the hippocampus, a deeper structure strongly associated with memory but shrouded in mystery about exactly how.

27 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Researchers investigate brain responses to aesthetically appealing natural landscapes

How does a view of nature gain its gloss of beauty? We know that the sight of beautiful landscapes engages the brain's reward systems.

23 Jul 2021

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

From the thrill of hearing an ice cream truck approaching to the spikes of pleasure while sipping a fine wine, the neurological messenger known as dopamine has been popularly described as the brain's "feel good" chemical related to reward and pleasure.

23 Jul 2021

Scientists uncover the early assembly of gamma-secretase involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

Molecular & Structural Biology

Scientists identify new therapeutic target for several aggressive cancers

Key protein linked to both physical fitness in youth and diseases of old age

Research shows how neurons learn to pick the most energy-efficient perturbations

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

Experimental model shows how topological defects in the mesothelium affect ovarian cancer metastasis

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Mini-antibodies efficiently block SARS-CoV-2 virus

Researchers create detailed molecular atlas of fetal development of the brain

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Research provides insights into how the hippocampus contributes to memory storage in the cortex

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Novel microfluidic device used to manipulate major whey protein

Researchers investigate brain responses to aesthetically appealing natural landscapes

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

Scientists uncover the early assembly of gamma-secretase involved in plaque production

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News