Molecular & Structural Biology

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Scientists develop new approach to identify proteins in the living brain

For the first time, researchers have developed a successful approach for identifying proteins inside different types of neurons in the brain of a living animal.

11 Aug 2021

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

A study at Tampere University has identified one possible epigenetic mechanism through which the conditions at conception may affect the health of an individual in later life.

10 Aug 2021

IMBA researchers may have found the "Achilles' heel" of SARS-CoV-2 virus

Researchers identify two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants.

10 Aug 2021

Functional brain connections explain readiness to punish others for unfair behavior

The stronger the functional brain connections, the less inclined someone is to punish others for unfair behavior.

10 Aug 2021

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

A potential new treatment for mast cell cancers reduces the number of mast cells by "mutating" the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation.

10 Aug 2021

Novel mechanistic insights on how ketamine exerts antidepressant effects

The discovery that the anaesthetic ketamine can help people with severe depression has raised hopes of finding new treatment options for the disease.

10 Aug 2021

Study finds altered brain gene expression patterns in people with opioid use disorder

The epidemic of opioid abuse affects millions of people worldwide, but researchers know surprisingly little about the molecular changes caused by opioids in the human brain.

10 Aug 2021

Novel imaging method shines new light on complex coordination molecules

Coordination compounds have molecular structures which consist of either one or multiple metal atoms at the center, surrounded by non-metal atoms.

10 Aug 2021

Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain

Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.

6 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress -; an imbalance in the normal oxidation/reduction homeostasis -; caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Researchers reveal key differences in the fragmentation of chiral biomolecules

By combining mass spectroscopy with further analytical and simulation techniques, researchers have revealed key differences in the fragmentation of dipeptide biomolecules with different chiral structures.

6 Aug 2021

SMC protein complex plays a decisive role in the dynamics of holocentromeres

Monocentromeres are typical for the chromosomes of most animals and plants. The centromere is necessary for the transport of the chromosomes and represents the connection point between the chromatids.

6 Aug 2021

Study: IgG antibodies against SARS-CoV-2 remain stable, or even increase, seven months after infection

The levels of IgG antibodies against SARS-CoV-2 Spike protein remain stable, or even increase, seven months after infection, according to a follow-up study in a cohort of healthcare workers coordinated by the Barcelona Institute for Global Health, an institution supported by "la Caixa" Foundation, in collaboration with the Hospital Clinic of Barcelona.

6 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

Scientists decipher missing pieces of the reward system puzzle to increase motivation

Our motivation to put effort into achieving a goal is controlled by a reward system wired in the brain. However, many neuropathological conditions impair the reward system, diminishing the will to work.

6 Aug 2021

Study reveals structural differences and unique polymorphs in amyloid-β fibrils

Alzheimer's disease (AD) is a neurological condition leading to dementia that worsens with age as patients exhibit cognitive, memory, and psychological deficits.

5 Aug 2021

UAB researchers identify potential therapeutic target for ovarian cancer

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers say in a study published in the journal Oncogenesis.

5 Aug 2021

Molecular & Structural Biology

Scientists develop new approach to identify proteins in the living brain

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

IMBA researchers may have found the "Achilles' heel" of SARS-CoV-2 virus

Functional brain connections explain readiness to punish others for unfair behavior

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Novel mechanistic insights on how ketamine exerts antidepressant effects

Study finds altered brain gene expression patterns in people with opioid use disorder

Novel imaging method shines new light on complex coordination molecules

Study uncovers link between corticosteroid receptors and ciliary, neuroplasticity genes in the brain

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Researchers reveal key differences in the fragmentation of chiral biomolecules

SMC protein complex plays a decisive role in the dynamics of holocentromeres

Study: IgG antibodies against SARS-CoV-2 remain stable, or even increase, seven months after infection

Researchers develop a novel process for producing pure RNA

Scientists decipher missing pieces of the reward system puzzle to increase motivation

Study reveals structural differences and unique polymorphs in amyloid-β fibrils

UAB researchers identify potential therapeutic target for ovarian cancer

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Researchers use tiny worm to trace the development of human brain

Study offers molecular views on how olfactory receptors work

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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