Molecular & Structural Biology

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Research explores the evolution and function of human growth hormone receptor gene

A new study delves into the evolution and function of the human growth hormone receptor gene and asks what forces in humanity's past may have driven changes to this vital piece of DNA.

25 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

Bubble and droplet formation theory inspires a framework for engineering living cells

The heady math that describes how bubbles form in a glass of Champagne has inspired a framework for engineering living cells.

23 Sep 2021

UW research provides a basic structure of neural networks in the mammalian brain

Two University of Wyoming researchers decided to pick each other's brain, so to speak. Specifically, they examined the importance of the frontal cortex, the portion of the brain used in decision-making, expressive language and voluntary movement.

22 Sep 2021

Researchers unravel the structure of bacterial appendages

A research team led by David Thanassi, PhD, of Stony Brook University, has used molecular biology and cryoelectron microscopy to successfully unravel the structure of bacterial appendages called P pili.

22 Sep 2021

Scientists use statistical mechanics to make sense of DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

New open-source, multi-disciplinary simulation platform to study biological processes

Agent-based simulations (ABS) are powerful computational tools that help scientists understand complex biological systems.

20 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

New study reveals chemical steps in an important cellular modification process

The chemical steps in an important cellular modification process that adds a chemical tag to some RNAs have been revealed in a new study. Interfering with this process in humans can lead to neuronal diseases, diabetes, and cancers.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Researchers develop a new tool to help provide early warning of rare and unknown viruses

Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses.

15 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

Research provides fundamental insight into motor planning under uncertainty

In baseball, a pitch can take as little as 400 milliseconds to reach the plate. With a typical reaction time of 200 milliseconds and a swing of about 150 milliseconds, a batter must decide whether to swing and how to swing based only on the first 10 to 20 percent of the ball's flight.

15 Sep 2021

Molecular & Structural Biology

Research explores the evolution and function of human growth hormone receptor gene

Study identifies master regulator behind the development of antibody-producing cells

Exploring the polymerase of poxviruses at an atomic level

Neuroscientists discover how associative memories are formed

Bubble and droplet formation theory inspires a framework for engineering living cells

UW research provides a basic structure of neural networks in the mammalian brain

Researchers unravel the structure of bacterial appendages

Scientists use statistical mechanics to make sense of DNA folding

Researchers provide structural insights into HCV receptor binding and entry

New open-source, multi-disciplinary simulation platform to study biological processes

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

New study reveals chemical steps in an important cellular modification process

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers develop a new tool to help provide early warning of rare and unknown viruses

Analysis of the immune landscape in mild-to-moderate COVID-19

Research provides fundamental insight into motor planning under uncertainty

A family of proteins may be able to outwit emerging and re-emerging viruses

A protein found to be effective at reversing aging in skeletal muscle cells

New slow-release system mimics nature to provide long-lasting local anesthesia

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

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