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COVID vaccines deployed in US highly effective at reducing hospitalizations and deaths

Researchers in the United States have conducted a large-scale study showing that the two-dose regimen vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) appear to be highly effective and durable in reducing the risk of hospitalizations and deaths following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Oct 2021

A low-cost repurposed drug can save COVID-19 patients' lives

An inexpensive repurposed drug called fluvoxamine can save the lives of COVID-19 patients and cut hospital admissions by up to 30 per cent, says a study co-led by McMaster University.

27 Oct 2021

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers emphasize that an effective vaccine should induce mucosal immunity and prevent the nasal entry of SARS-CoV-2.

27 Oct 2021

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not intentionally targeted by any available therapeutics but is widely expressed in human melanoma.

27 Oct 2021

Pharma campaign cash delivered to key lawmakers with surgical precision

The Biden administration and Congress are embroiled in high-stakes haggling over what urgent priorities will make it into the ever-shrinking social spending bill.

27 Oct 2021

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

In the worldwide effort to battle SARS-CoV-2, the virus that causes COVID-19, researchers have often turned to medications used as therapies for other conditions in the hopes of finding ones that either kill the coronavirus or lessen the impacts from its infection.

26 Oct 2021

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Israeli researchers evaluate the antibody response in ICPs to assess antibody-mediated immunity following vaccination with the Pfizer-BioNTech vaccine.

26 Oct 2021

Stimulant use linked with increased risk of cardiovascular events among older adults in the first month

New research led by Mina Tadrous, Assistant Professor, Leslie Dan Faculty of Pharmacy, University of Toronto shows that use of prescription stimulant medications in older adults increased the risk of a cardiovascular events by 40 per cent within the first thirty days of medication use.

25 Oct 2021

A comparison between Pfizer/BioNTech's and Sinopharm's SARS-CoV-2 vaccines

Researchers compare antibody titers elicited the Pfizer‐BioNTech mRNA and the classic inactivated virus Sinopharm vaccines.

24 Oct 2021

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Researchers report the binding and pseudo-neutralizing antibody titers elicited after patients had received either the Pfizer-BioNTech or AstraZeneca vaccines.

24 Oct 2021

Vaccination data from Puerto Rico strongly supports COVID19 booster shots

In a recent study, researchers from the U.S. examined the vaccine effectiveness against SARS-CoV-2 infections in Puerto Rico.

24 Oct 2021

Antidepressant offers no improvement in agitation for people with dementia, study shows

A drug used to treat agitation in people with dementia is no more effective than a placebo, and might even increase mortality, according to a new study.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Comparative effectiveness of ChAdOx1 and BNT162b2 COVID-19 vaccines

In a recent study, researchers compared the efficacy of the Pfizer-BioNTech and Oxford-AstraZeneca COVID-19 vaccines against infection SARS-CoV-2.

21 Oct 2021

Antidepressant Prozac could offer the first treatment for atrophic macular degeneration

An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine suggests.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Drug company pipelines are filling up with new molecules to help people lose weight

Drugs that promise to help people lose weight have had a checkered past, such as the infamous fen-phen that was pulled from the market in 1997 after reports of heart valve damage. But now, drug company pipelines are filling up with new molecules that aim to help people safely shed extra pounds, according to a cover story in Chemical & Engineering News, an independent news outlet of the American Chemical Society.

21 Oct 2021

Pharmaceutical News

COVID vaccines deployed in US highly effective at reducing hospitalizations and deaths

A low-cost repurposed drug can save COVID-19 patients' lives

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

Pharma campaign cash delivered to key lawmakers with surgical precision

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Stimulant use linked with increased risk of cardiovascular events among older adults in the first month

A comparison between Pfizer/BioNTech's and Sinopharm's SARS-CoV-2 vaccines

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Vaccination data from Puerto Rico strongly supports COVID19 booster shots

Antidepressant offers no improvement in agitation for people with dementia, study shows

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Comparative effectiveness of ChAdOx1 and BNT162b2 COVID-19 vaccines

Antidepressant Prozac could offer the first treatment for atrophic macular degeneration

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Drug company pipelines are filling up with new molecules to help people lose weight

How the public views COVID-19 vaccines via Twitter in the United States

New research on phagocytosis and SARS-CoV-2's spike protein

Commonly prescribed medications can make the flu virus more or less active

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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