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Alzheimer’s drug targets people with mild cognitive impairment. What does that mean?

The approval of a controversial new drug for Alzheimer's disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging.

29 Sep 2021

A retrospective surveillance study of Pfizer–BioNTech BNT162b2 mRNA COVID-19 vaccination in Israel

One recent study provided nationwide estimates of the burden of SARS-CoV-2 that could be averted by Israel's vaccination campaign.

28 Sep 2021

Trial of Sanofi/GSK SARS-CoV-2 vaccine boosters against variants in non-human primates

New research discusses the development of soluble prefusion-stabilized spike trimers (CoV2 preS dTM) comprising adjuvant AS03.

27 Sep 2021

Limited evidence colchicine reduces COVID-19 related hospitalization

The present randomized clinical trial attempted to study if colchicine will effectively hasten recovery and reduce COVID-19 associated hospitalizations or death.

27 Sep 2021

Widely used osteoporosis drug protects against type 2 diabetes, says research

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, suggests that the widely used osteoporosis drug alendronate reduces the risk of type 2 diabetes.

27 Sep 2021

WHO urges to address the high price and limited production of antibody combination for COVID-19

The World Health Organization (WHO) welcomes the addition of another therapeutic to the world's arsenal against COVID-19, but urges producing companies and governments to address the high price and limited production of the Regeneron antibody combination and ensure safe and appropriate handling of the medicine.

27 Sep 2021

A review of drugs harmful in COVID-19

In a new study, researchers investigate a number of drugs that are believed to potentially worsen outcomes in patients with COVID-19.

26 Sep 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell.

24 Sep 2021

A daily pill to treat covid could be just months away, scientists say

Within a day of testing positive for covid-19 in June, Miranda Kelly was sick enough to be scared. At 44, with diabetes and high blood pressure, Kelly, a certified nursing assistant, was having trouble breathing, symptoms serious enough to send her to the emergency room.

24 Sep 2021

Domestic reference pricing may reduce Medicare expenditures on new drugs, study finds

Basing new drug launch prices on historical domestic data could limit manufacturers' power to set extremely high launch prices and could reduce Medicare spending on new drugs by up to 30%, according to a new white paper released today by West Health and its Council for Informed Drug Spending Analysis.

23 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

It took years for Elle Moxley to get a diagnosis that explained her crippling gastrointestinal pain, digestion problems, fatigue, and hot, red rashes.

23 Sep 2021

Study finds rise in methamphetamine-involved overdose deaths from 2015 to 2019

Overdose deaths involving methamphetamine nearly tripled from 2015 to 2019 among people ages 18-64 in the United States, according to a study by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

22 Sep 2021

Implications of dosing sparing and booster shots in the context of prior SARS-CoV-2 infection

The current study suggests that deferring the second vaccination of individuals with prior infection may be a cost-effective strategy.

21 Sep 2021

Is the Pfizer-BioNTech COVID vaccine still effective after 6 months?

A team of researchers assessed the effectiveness of the Pfizer-BioNTech BNT162b2 mRNA COVID-19 vaccine.

21 Sep 2021

COVID-19 vaccine effectiveness against SARS-CoV-2 variants

A commentary published in the journal Cell summarizes international data on vaccine effectiveness against new severe acute respiratory coronavirus 2 (SARS-CoV-2) variants. Evidence shows that the currently approved vaccines continue to be effective in preventing severe and symptomatic illness — even with the widely circulating Delta variant.

21 Sep 2021

Popular class of diabetes medications may be protective against glaucoma

A popular class of diabetes medications called GLP-1R agonists (Trulicity and Rybelsus) may also protect against glaucoma in diabetic patients, according to a new study led by researchers in the Scheie Eye Institute at the University of Pennsylvania's Perelman School of Medicine.

20 Sep 2021

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

Development of a potential pan-variant aerosol to manage COVID-19

Researchers hypothesized that if APN01 could be directly introduced into the airways of an infected person, it could locally neutralize SARS-CoV-2.

19 Sep 2021

'Spice' users likely to experience more severe withdrawal symptoms, study finds

Research published today by psychologists at the University of Bath suggests that 'Spice' – which contains synthetic drugs originally designed to mimic the effects of cannabis – is more harmful than cannabis and that users are likely to experience more severe withdrawal symptoms when attempting to quit.

18 Sep 2021