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Study demonstrates the potency of herbal medicines against Bartonella henselae

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data showing that herbal medicines have potent activity in test tubes compared to pharmaceuticals commonly-prescribed for the treatment of Bartonella henselae, a bacterium believed to be carried by ticks and the cause of cat scratch fever.

5 Aug 2021

2+2=? Senate uses murky math as it shelves drug pricing rule to fund infrastructure

The Senate’s release of its bipartisan infrastructure plan signals that lawmakers are poised to throw former President Donald Trump’s belated bid to lower Medicare drug prices under the bus — not to mention trains, bridges, tunnels and broadband connections.

5 Aug 2021

Inhibition of SARS-CoV-2 replication in vitro by Losartan

A new study explores the use of Losartan to provide protection against COVID-19 pathogenesis.

3 Aug 2021

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

Scientists evaluate the use of ChAdOx1 nCoV-19 as a potential intranasal (IN) vaccine candidate in hamster and rhesus macaque models.

3 Aug 2021

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Opioid therapy is complex. In recent years, a rise in opioid-related deaths and changing prescribing guidelines and regulatory policies have led many physicians to reduce daily doses for patients prescribed stable opioid therapy for chronic pain.

3 Aug 2021

Study finds a significant link between statins and survival rates of triple-negative breast cancer patients

A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

3 Aug 2021

Anti-parasitic drug prevents pancreatic cancer's initiation, progression and metastasis in mice

As the third-most lethal cancer in the United States, with only a 1% five-year survival rate for people with its most aggressive form, pancreatic cancer has long been a target of researchers who search for ways to slow or stop its growth and spread.

3 Aug 2021

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers in the United States have described a novel antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being evaluated in clinical trials as a treatment for coronavirus disease 2019 (COVID-19).

2 Aug 2021

Existing drug may be effective in treating SARS-CoV-2

Scientists from the University of Chicago have found that the drug masitinib may be effective in treating COVID-19.

2 Aug 2021

FDA's accelerated drug approval process plagued by missing efficacy data and questionable evidence

Since the US Food and Drug Administration established its accelerated approval pathway for drugs in 1992, nearly half of the 253 drugs authorized have not been confirmed as clinically effective, an investigation by The BMJ has found.

31 Jul 2021

New advice: Antibiotics should not be given to kids as a preventative measure to avoid UTIs

Antibiotics shouldn’t be given to children as a preventative measure to try to avoid another urinary tract infection for kids who have already had one infection, as it’s unlikely to prevent another UTI and also contributes to the growing problem of antibiotic resistance.

31 Jul 2021

Pfizer court fight could legalize Medicare copays and unleash ‘gold rush’ in sales

Three years ago, pharma giant Pfizer paid $24 million to settle federal allegations that it was paying kickbacks and inflating sales by reimbursing Medicare patients for out-of-pocket medication costs.

29 Jul 2021

SARS-CoV-2 Beta variant marginally affects Pfizer vaccination efficacy in fully vaccinated

Researchers from Israel recently evaluated the efficacy of the Pfizer vaccine against the SARS-CoV-2 B.1.351 variant.

28 Jul 2021

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

A team of international scientists has recently developed virus-like particles (VLPs) by coating liposomes with the synthetic spike glycoprotein of SARS-CoV-2.

28 Jul 2021

First interchangeable biosimilar insulin product approved by FDA for treatment of diabetes

Today, the U.S. Food and Drug Administration approved the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus.

28 Jul 2021

Systematic review explores the effects of ivermectin in preventing and treating COVID-19

Ivermectin, a drug used to treat parasites such as scabies in humans and intestinal helminths in cattle, was screened in 2020 for activity against COVID-19. Laboratory tests suggested a weak effect on SARS-CoV-2 virus in a test tube but did not seem feasible in humans as the doses needed would be large.

28 Jul 2021

Budesonide’s antiviral effect against SARS-CoV-2

A new study examines the in vitro antiviral effect of pure budesonide and Pulmicort® against the SARS-CoV-2 WT and two VoCs.

26 Jul 2021

More popular type of antihypertensive drugs causes slightly more side effects

Two types of drugs that are recommended as a first treatment for patients with high blood pressure were found equally effective in improving cardiovascular outcomes, but the more popular type causes slightly more side effects, finds a multinational observational study led by researchers at Columbia University Vagelos College of Physicians and Surgeons.

26 Jul 2021

Two types of blood pressure drugs provide equal benefits, but side effects differ

People who are just beginning treatment for high blood pressure can benefit equally from two different classes of medicine - angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) - yet ARBs may be less likely to cause medication side effects, according to an analysis of real-world data published today in Hypertension, an American Heart Association journal.

26 Jul 2021

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

A new study published on the preprint server medRxiv* presents an analysis of the differences between recorded vaccination side effects vs. early COVID-19 symptoms. The researchers focused on four vaccines, namely, Pfizer-BioNTech (PB) mRNA (BNT162b2) vaccine, based on messenger ribonucleic acid encoding the viral spike protein; the Moderna mRNA (mRNA-1273) vaccine; the Oxford-AstraZeneca (O-AZ) adenovirus-vectored vaccine; and the Janssen adenovirus-vectored Ad26.COV2.S).

26 Jul 2021

Pharmaceutical News

Study demonstrates the potency of herbal medicines against Bartonella henselae

2+2=? Senate uses murky math as it shelves drug pricing rule to fund infrastructure

Inhibition of SARS-CoV-2 replication in vitro by Losartan

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Study finds a significant link between statins and survival rates of triple-negative breast cancer patients

Anti-parasitic drug prevents pancreatic cancer's initiation, progression and metastasis in mice

Pfizer moves towards an oral anti-COVID-19 therapy

Existing drug may be effective in treating SARS-CoV-2

FDA's accelerated drug approval process plagued by missing efficacy data and questionable evidence

New advice: Antibiotics should not be given to kids as a preventative measure to avoid UTIs

Pfizer court fight could legalize Medicare copays and unleash ‘gold rush’ in sales

SARS-CoV-2 Beta variant marginally affects Pfizer vaccination efficacy in fully vaccinated

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

First interchangeable biosimilar insulin product approved by FDA for treatment of diabetes

Systematic review explores the effects of ivermectin in preventing and treating COVID-19

Budesonide’s antiviral effect against SARS-CoV-2

More popular type of antihypertensive drugs causes slightly more side effects

Two types of blood pressure drugs provide equal benefits, but side effects differ

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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