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FDA approves new treatment for patients with hypoplasminogenemia

Today, the U.S. Food and Drug Administration approved Ryplazim (plasminogen, human-tmvh) for the treatment of patients with plasminogen deficiency type 1, also referred to as hypoplasminogenemia, a disorder that can impair normal tissue and organ function and may lead to blindness.

5 Jun 2021

Study elucidates the use of anticoagulants to treat bleeding in patients with gastrointestinal cancers

A study by Mayo Clinic researchers provides some clarity in the use of direct oral anticoagulants (DOAC), such as apixaban and rivaroxaban, to treat acute venous thromboembolism (VTE) in patients with gastrointestinal cancers.

5 Jun 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

The Food and Drug Administration's decision next week whether to approve the first treatment for Alzheimer's disease highlights a deep division over the drug's benefits as well as criticism about the integrity of the FDA approval process.

4 Jun 2021

New strategy for developing universal flu vaccine

A new study from the University of Chicago and Scripps Research Institute shows that during the last great pandemic--2009's H1N1 influenza pandemic--people developed strong, effective immune responses to stable, conserved parts of the virus.

4 Jun 2021

Majority of Republicans support Medicare negotiation on drug prices

A new West Health/Gallup survey finds nearly all Democrats (97%) and the majority of Republicans (61%) support empowering the federal government to negotiate lower prices of brand-name prescription drugs covered by Medicare.

4 Jun 2021

FDA issues new guidance to improve quality and security of prescription drugs in the U.S. supply chain

The following quote is attributed to Donald D. Ashley, J.D., Director of the Office of Compliance for FDA's Center for Drug Evaluation and Research

4 Jun 2021

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

4 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

Study highlights surging trends in prescriptions and costs of antidepressants

Researchers at the University of Huddersfield have warned there is an urgent need for the country's mental health interventions to create strategies optimizing the use of antidepressants after conducting a study which has highlighted an alarming rise in relation to usage and costs.

3 Jun 2021

KHN’s ‘What the Health?’: The drug price dilemma

The high cost of prescription drugs is among consumers' top health policy issues, according to public opinion polls.

3 Jun 2021

Study reveals prevalence of multimorbidity among people using methamphetamine

People who use methamphetamine are more likely to have health conditions, mental illness, and substance use disorders than people who do not use the drug, according to a new study by researchers at the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health.

3 Jun 2021

Study compares Pfizer and Moderna mRNA vaccine-elicited response to SARS-CoV-2 variants

A new study has been published on the bioRxiv preprint server which focuses on the correlation between the vaccine-triggered Immunoglobulin G (IgG) levels and neutralization titers against SARS-CoV-2 variants. Further, neutralization activities against the variants (B.1.1.7, B.1.525, and B.1.351), using Pfizer or Moderna vaccine, sera were assessed.

3 Jun 2021

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Oncotarget published "A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas" which reported that the incidence of human papillomavirus-positive head and neck squamous cell carcinoma has increased dramatically over the past decades due to an increase in infection of the oral mucosa by HPV.

3 Jun 2021

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

However, a fascinating new study posted to the medRxiv* preprint server suggests that such disappointment may have been both premature and unwarranted, based on a re-analysis of over 250 patients on invasive mechanical ventilation (IMV) during the first two months of the pandemic.

2 Jun 2021

Most prescriptions for buprenorphine are written by a small number of health care providers

Most prescriptions for the drug buprenorphine, used to treat opioid use disorder, are written by a small number of the health care providers, according to a new RAND Corporation study.

2 Jun 2021

Childhood vaccination rates in Texas have dropped steeply during COVID-19 pandemic

A team of researchers from universities in California and Texas has found immunization rates for children in Texas for a wide range of diseases, including polio and measles, have dropped steeply during the COVID-19 pandemic.

2 Jun 2021

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected.

2 Jun 2021

Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment

They have identified a group of kite-shaped compounds that are highly specific to SARS-CoV-1 and SARS-CoV-2. These compounds demonstrate high potency in inhibiting SARS-CoV-2 infection at early entry steps. The study is currently available on the bioRxiv* preprint server.

2 Jun 2021

Old vaccines can stimulate the immune system to provide protection against other infectious diseases

Inoculation with live attenuated vaccines (LAV) such as those used against TB, polio or measles can stimulate the immune system to provide protection against other infectious diseases, including COVID-19, says a new study.

2 Jun 2021

Pharmaceutical News

FDA approves new treatment for patients with hypoplasminogenemia

Study elucidates the use of anticoagulants to treat bleeding in patients with gastrointestinal cancers

Weight loss drug Wegovy approved by FDA

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

New strategy for developing universal flu vaccine

Majority of Republicans support Medicare negotiation on drug prices

FDA issues new guidance to improve quality and security of prescription drugs in the U.S. supply chain

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

Study highlights surging trends in prescriptions and costs of antidepressants

KHN’s ‘What the Health?’: The drug price dilemma

Study reveals prevalence of multimorbidity among people using methamphetamine

Study compares Pfizer and Moderna mRNA vaccine-elicited response to SARS-CoV-2 variants

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients

Most prescriptions for buprenorphine are written by a small number of health care providers

Childhood vaccination rates in Texas have dropped steeply during COVID-19 pandemic

Scientists test antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus

Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment

Old vaccines can stimulate the immune system to provide protection against other infectious diseases

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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