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The COVID-19 vaccine pipeline

Researchers from Mayo Clinic, United States of America, have reviewed the immunity developed against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

14 Oct 2020

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Today, the U.S. Food and Drug Administration approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients.

14 Oct 2020

Study: Public messaging should be communicated before the availability of COVID-19 vaccines

A new study indicates some significant public messaging should be communicated before any COVID-19 vaccines are made available in the US. And with vaccines potentially being approved by the end of the year or early next year, the clock is ticking.

14 Oct 2020

Researchers create multi-functional nano-vaccine to prevent toxoplasmosis

Fighting clever parasites requires smart vaccines that can trigger critical immune responses. A University of Chicago-based research team has found a novel way to do that.

14 Oct 2020

Research shows 10 or more medications are prescribed to older heart failure patients

More than half of older patients hospitalized for heart failure, a progressive condition in which the heart doesn't pump blood as well as it should, are discharged from the hospital with prescriptions for 10 or more medications, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

13 Oct 2020

Optimizing allocation of future COVID-19 vaccine can double effectiveness

In anticipation of coronavirus disease (COVID-19) vaccine deployment, the Australian and US researchers utilized an age-structured mathematical model to appraise the potential benefits of optimizing age-specific dose allocation for suppressing SARS-CoV-2 transmission – and reaffirmed the notion that vaccination alone may be inadequate to achieve herd immunity in some settings. The study is currently available on the medRxiv* preprint server.

12 Oct 2020

New study may lead to more effective, personalized cancer immunotherapies

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

12 Oct 2020

Study shows unique cardioprotective properties of an old drug

A drug costing less than 2 euros per dose could reduce the long term consequences of a heart attack, benefitting millions of patients. Metoprolol, a member of the beta-blocker class of drugs that has been in use for more than 40 years, has been found to have unique cardioprotective properties.

9 Oct 2020

As Trump touts his ‘great’ COVID drugs, the pharma cash flows to Biden, not him

Pharmaceutical giants Regeneron and Gilead Sciences got the kind of publicity money can't buy this week after President Donald Trump took their experimental drugs for his coronavirus infection, left the hospital and pronounced himself fully recovered.

9 Oct 2020

Study: New viral mutations would not impact the efficacy of Covid-19 vaccine candidates

Vaccines currently being developed for Covid-19 should not be affected by recent mutations in the virus, according to a new study involving a University of York virologist.

8 Oct 2020

Study: Cannabis seldom serves as substitute for non-medical opioids

A study published in the scientific journal Addiction suggests that, contrary to what some are claiming, people in the US may not be substituting cannabis for opioids.

8 Oct 2020

Researcher receives NIH award to explore effect of women's hormones on postpartum opioid relapse

When most people think of opioid addiction, they typically do not think of pregnant women. Unfortunately, however, the prevalence of opioid addiction during pregnancy has increased nearly 500% during the past 15 years.

8 Oct 2020

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene.

8 Oct 2020

DARPA selects Purdue-affiliated company to develop continuous manufacturing technology

The COVID-19 pandemic has created supply chain gaps in critical drug products, especially those needed for the most critical patients in intensive care units across the country.

7 Oct 2020

Sofosbuvir combined with other antivirals is more effective against COVID-19, shows study

Columbia Engineering researchers report that Sofosbuvir-terminated RNA is more resistant to the proofreader of SARS-CoV-2, the virus that causes COVID-19, than Remdesivir-terminated RNA.

7 Oct 2020

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

Only about one in every 170 children take them. But "orphan drugs" accounted for 1 in every 15 private insurance dollars spent on children's health care in the United States in 2018, according to a new study. That's up 65% from just five years before.

6 Oct 2020

Antibiotics might be a feasible treatment option for appendicitis, shows study

Henry Ford Health System surgeons involved in the study say patients should choose the best option in consultation with their physician.

6 Oct 2020

New drug offers a promising treatment for neuroblastoma

A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine.

6 Oct 2020

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

A postdoctoral researcher at the University of California, Riverside, has discovered human papillomavirus, or HPV, vaccination mandates fall short of ensuring both higher levels of uptake and equal uptake of the vaccine across socioeconomic and racial-ethnic groups.

6 Oct 2020

New guidelines reduce number of opioid pills prescribed to patients after surgery

To address the opioid epidemic, surgeons have embraced guidelines to reduce the number of opioid pills they prescribe to patients after surgery, and the efforts have helped to significantly reduce the number of opioids in circulation.

5 Oct 2020

Pharmaceutical News

The COVID-19 vaccine pipeline

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Study: Public messaging should be communicated before the availability of COVID-19 vaccines

Researchers create multi-functional nano-vaccine to prevent toxoplasmosis

Research shows 10 or more medications are prescribed to older heart failure patients

Optimizing allocation of future COVID-19 vaccine can double effectiveness

New study may lead to more effective, personalized cancer immunotherapies

Study shows unique cardioprotective properties of an old drug

As Trump touts his ‘great’ COVID drugs, the pharma cash flows to Biden, not him

Study: New viral mutations would not impact the efficacy of Covid-19 vaccine candidates

Study: Cannabis seldom serves as substitute for non-medical opioids

Researcher receives NIH award to explore effect of women's hormones on postpartum opioid relapse

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

DARPA selects Purdue-affiliated company to develop continuous manufacturing technology

Sofosbuvir combined with other antivirals is more effective against COVID-19, shows study

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

Antibiotics might be a feasible treatment option for appendicitis, shows study

New drug offers a promising treatment for neuroblastoma

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

New guidelines reduce number of opioid pills prescribed to patients after surgery

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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