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Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023

Americans will spend a larger share of their lifetime taking prescription drugs, research finds

An American born in 2019 will spend a larger share of their lifetime taking prescription drugs than being married or receiving an education, according to new research by Jessica Ho, associate professor of sociology and demography at Penn State.

12 Oct 2023

Study reassures patients on safety of widely prescribed hypertension drug amlodipine

A new paper in the journal Function, published by Oxford Univetrsity Press, finds that a widely prescribed drug for treating hypertension, amlodipine, is not dangerous for patients, despite recent concerns from researchers and clinicians that taking amlodipine may have risks.

12 Oct 2023

Researchers call for urgent improvement in pain management for inflammatory arthritis patients

Researchers from Keele University's School of Medicine have found that analgesic medicines - commonly known as "painkillers" - are widely prescribed to people with inflammatory arthritis across England despite little research evidence that they improve pain for these patients, and studies showing they can cause serious side-effects.

12 Oct 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

Maternal pertussis vaccination boosts infant protection up to eight months

In a large-scale Australian study, maternal vaccination during pregnancy significantly increased pertussis resistance in infants up to eight months. While it slightly reduced the effectiveness of infants' routine vaccinations, it did not increase infection risk.

11 Oct 2023

Finerenone: A promising therapeutic option for cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mineralocorticoid receptor antagonists (MRA) have significant therapeutic effects on heart failure, hypertension, chronic kidney disease and primary aldosteronism.

11 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Intermittent use of benzodiazepines linked with fewer side effects

More than 60 years after being introduced, doctors have uncovered the first reliable evidence to confirm the belief that taking benzodiazepines such as Valium and Ativan intermittently rather than continuously is associated with fewer side effects and reduced falls, hospitalizations and deaths.

9 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Intrusive thoughts, involuntary repetition of undesirable gestures and behaviors combined with high anxiety... Obsessive-compulsive disorder (OCD), a disabling condition, affects around 2% of the population, regardless of age.

9 Oct 2023

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

Recent study assesses NVX-CoV2373 vaccine's effectiveness against Omicron variant. Findings show decreased efficacy over four months, but stable protection against symptomatic COVID-19.

8 Oct 2023

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Researchers investigate whether ribavirin and pleconaril could stimulate endogenous insulin production among individuals with incident type 1 diabetes.

8 Oct 2023

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Nirmatrelvir and ritonavir treatment significantly reduces the risk of hospitalization and death from COVID-19 in high-risk individuals, according to a recent JAMA Network Open study. However, the treatment's efficacy varied based on the degree of vulnerability, emphasizing tailored approaches for different risk groups.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Trump misplaced blame when he said drug shortages were Biden’s fault

"Under 'Crooked Joe' Biden, there has been a catastrophic increase in shortages of essential medicines."

6 Oct 2023

Why are most Americans skipping the COVID-19 booster?

A study in the journal Vaccine reveals that misinformation and concerns about side effects are leading reasons why over 80% of eligible Americans have skipped the SARS-CoV-2 vaccine booster. The research underscores the need for more public education about the vaccine's benefits in combating severe COVID-19 infections.

5 Oct 2023

How is TikTok's #Ozempic trend impacting diabetes patients?

A recent study analyzed TikTok videos with the hashtag "Ozempic," highlighting the platform's influence on promoting the weight loss drug. The surge in popularity resulted in medication shortages for diabetes patients, emphasizing the need for careful monitoring and collaboration among health professionals and social media platforms.

5 Oct 2023

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Pharmaceutical News

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Americans will spend a larger share of their lifetime taking prescription drugs, research finds

Study reassures patients on safety of widely prescribed hypertension drug amlodipine

Researchers call for urgent improvement in pain management for inflammatory arthritis patients

Does your gut microbiome play a role in therapeutic outcomes?

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Maternal pertussis vaccination boosts infant protection up to eight months

Finerenone: A promising therapeutic option for cardiovascular diseases

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

Intermittent use of benzodiazepines linked with fewer side effects

Research explains the reason behind delay in therapeutic action of antidepressants

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

Trump misplaced blame when he said drug shortages were Biden’s fault

Why are most Americans skipping the COVID-19 booster?

How is TikTok's #Ozempic trend impacting diabetes patients?

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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