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New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

The study explores the efficacy of variant-adapted COVID-19 booster vaccines, particularly against new strains like Omicron. It raises questions about the need for annual updates and the best technologies for long-term, durable immunity.

15 Oct 2023

Aureane-type sesquiterpene tetraketides hold great promise in treating IL-17A-mediated immune diseases

This new article publication from Acta Pharmaceutica Sinica B, discusses aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity.

15 Oct 2023

New TB treatments tackle the disease without wrecking your microbiome

Researchers in a study published in The Lancet Microbe examined how various tuberculosis treatment regimens affect the respiratory microbiome. They found that certain treatments control tuberculosis effectively while minimally impacting the diversity and health of the respiratory microbiome.

15 Oct 2023

Pfizer Australia and BioNTech announce TGA approval for Omicron XBB.1.5-adapted monovalent COVID-19 vaccine

Pfizer Australia and BioNTech SE today announced that the Therapeutic Goods Administration (TGA) have authorised the companies’ XBB.1.5-adapted monovalent COVID-19 vaccine (COMIRNATY® Omicron XBB.1.5) in individuals 5 years and older.

14 Oct 2023

Opioid prescribing limits may not worsen patient experience after common surgeries

Worries that surgery patients would have a tougher recovery if their doctors had to abide by a five-day limit on opioid pain medication prescriptions didn't play out as expected, a new study finds.

13 Oct 2023

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Moderna's updated mRNA-1273.815 COVID-19 vaccine shows promising results in reducing symptomatic cases, hospitalizations, and deaths in high-risk and older adults in Germany. The study finds the vaccine to be more cost-effective and clinically beneficial than both no vaccination and Pfizer's XBB.1.5 BNT162b2 vaccine.

12 Oct 2023

Ketamine shows complex influence on social cognition in schizophrenia, study reveals

Researchers from the University of Bonn delve into the complex relationship between ketamine and social cognition deficits in schizophrenia, revealing both promising and cautionary insights.

12 Oct 2023

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants' actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

12 Oct 2023

Americans will spend a larger share of their lifetime taking prescription drugs, research finds

An American born in 2019 will spend a larger share of their lifetime taking prescription drugs than being married or receiving an education, according to new research by Jessica Ho, associate professor of sociology and demography at Penn State.

12 Oct 2023

Study reassures patients on safety of widely prescribed hypertension drug amlodipine

A new paper in the journal Function, published by Oxford Univetrsity Press, finds that a widely prescribed drug for treating hypertension, amlodipine, is not dangerous for patients, despite recent concerns from researchers and clinicians that taking amlodipine may have risks.

12 Oct 2023

Researchers call for urgent improvement in pain management for inflammatory arthritis patients

Researchers from Keele University's School of Medicine have found that analgesic medicines - commonly known as "painkillers" - are widely prescribed to people with inflammatory arthritis across England despite little research evidence that they improve pain for these patients, and studies showing they can cause serious side-effects.

12 Oct 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

Maternal pertussis vaccination boosts infant protection up to eight months

In a large-scale Australian study, maternal vaccination during pregnancy significantly increased pertussis resistance in infants up to eight months. While it slightly reduced the effectiveness of infants' routine vaccinations, it did not increase infection risk.

11 Oct 2023

Finerenone: A promising therapeutic option for cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mineralocorticoid receptor antagonists (MRA) have significant therapeutic effects on heart failure, hypertension, chronic kidney disease and primary aldosteronism.

11 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Intermittent use of benzodiazepines linked with fewer side effects

More than 60 years after being introduced, doctors have uncovered the first reliable evidence to confirm the belief that taking benzodiazepines such as Valium and Ativan intermittently rather than continuously is associated with fewer side effects and reduced falls, hospitalizations and deaths.

9 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Intrusive thoughts, involuntary repetition of undesirable gestures and behaviors combined with high anxiety... Obsessive-compulsive disorder (OCD), a disabling condition, affects around 2% of the population, regardless of age.

9 Oct 2023

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Pharmaceutical News

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

Aureane-type sesquiterpene tetraketides hold great promise in treating IL-17A-mediated immune diseases

New TB treatments tackle the disease without wrecking your microbiome

Pfizer Australia and BioNTech announce TGA approval for Omicron XBB.1.5-adapted monovalent COVID-19 vaccine

Opioid prescribing limits may not worsen patient experience after common surgeries

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Ketamine shows complex influence on social cognition in schizophrenia, study reveals

Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Americans will spend a larger share of their lifetime taking prescription drugs, research finds

Study reassures patients on safety of widely prescribed hypertension drug amlodipine

Researchers call for urgent improvement in pain management for inflammatory arthritis patients

Does your gut microbiome play a role in therapeutic outcomes?

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Maternal pertussis vaccination boosts infant protection up to eight months

Finerenone: A promising therapeutic option for cardiovascular diseases

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

Intermittent use of benzodiazepines linked with fewer side effects

Research explains the reason behind delay in therapeutic action of antidepressants

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

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