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Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

In a new study titled, "Understanding Feeling 'High' and Its Role in Medical Cannabis Patient Outcomes," published in the journal, Frontiers in Pharmacology, researchers at The University of New Mexico, in collaboration with Releaf App™ found that patients who reported feeling "High" experienced 7.7% greater symptom relief and an increase in reporting of positive side effects such as "Relaxed" and "Peaceful."

22 Jun 2023

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Researchers examined the effectiveness and safety of using Panax notoginseng saponins for ischemic stroke in adults.

22 Jun 2023

Repurposing cancer drugs for malaria treatment

With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.

21 Jun 2023

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

Ketone supplements used by some athletes may worsen performance

Kinesiologists at McMaster University have found ketone supplements, used by some athletes hoping to cross the finish line faster, may in fact worsen performance.

21 Jun 2023

Hypertension drug shown to prevent post-traumatic headaches

A study led by VA Puget Sound Health Care System researchers has shown that prazosin, a drug used to treat high blood pressure, can prevent posttraumatic headaches.

21 Jun 2023

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

A new research paper was published in Oncotarget's Volume 14 on June 19, 2023, entitled, "Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer."

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Comparing the cost-effectiveness of SGLT2i versus mineralocorticoid antagonists

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are approved for heart failure with reduced ejection fraction (HFrEF).

19 Jun 2023

Smart drugs fall short as cognitive function enhancers

A recent Science Advances study investigated the effectiveness of three popular smart drugs, namely, modafinil (MOD), methylphenidate (MPH), and dextroamphetamine (DEX), against the difficulty of real-life daily tasks, i.e., the 0-1 knapsack optimization problem (“knapsack task”). A knapsack task is basically a combinatorial optimization task, the class of NP-time challenging problems.

18 Jun 2023

Herbal extracts for mental health: Are they safe for pregnant women?

Researchers evaluate the T-cell modulating effects of St. John’s wort, valerian, hops, lavender, and California poppy.

18 Jun 2023

Injectable osteoporosis drug can be safely administered orally using a novel 'robotic pill'

A proven and effective medication for osteoporosis, which is currently only available as an injection, can be administered orally using a novel "robotic pill," according to a study presented Saturday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Reform of EU pharmaceutical legislation: Improving access to innovative drugs at the national level

The European Commission's stated aim is to improve access to innovative drugs at the national level throughout the EU.

16 Jun 2023

Opioid settlement payouts to localities made public for first time

Thousands of local governments nationwide are receiving settlement money from companies that made, sold, or distributed opioid painkillers, like Johnson & Johnson, AmerisourceBergen, and Walmart.

16 Jun 2023

Overly restricting opioid use during surgery may be doing more harm than good

Because of the opioid crisis, physicians are less likely to administer opioids to help manage patients' pain, even in the operating room.

15 Jun 2023

Study: Some breast cancer drugs may lessen the effect of weight loss medications

Breast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presented Friday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

A medication called bempedoic acid reduced the risk of cardiac events as well as statins and may offer an alternative to the popular cholesterol-reducing medications, according to industry-supported research being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting, in Chicago, Ill.

15 Jun 2023

Study reveals sharp increase in hospital encounters for benzodiazepine-related toxicity among youth

The rate of hospital encounters for benzodiazepine-related toxicity rose by 67 per cent for young adults (aged 19 to 24) and 44 per cent for youth (aged 18 or below) in Ontario between 2013 and 2020, according to a new study from ICES and Unity Health Toronto.

15 Jun 2023

Study examines the drivers of specialty drug diffusion

Researchers from McGill University and Ontario Tech University published a new Journal of Marketing article that examines the drivers of specialty drug diffusion.

15 Jun 2023

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Pharmaceutical News

Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Repurposing cancer drugs for malaria treatment

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ketone supplements used by some athletes may worsen performance

Hypertension drug shown to prevent post-traumatic headaches

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Battle against RSV: Computational design paves way for new polyvalent vaccine

Comparing the cost-effectiveness of SGLT2i versus mineralocorticoid antagonists

Smart drugs fall short as cognitive function enhancers

Herbal extracts for mental health: Are they safe for pregnant women?

Injectable osteoporosis drug can be safely administered orally using a novel 'robotic pill'

Reform of EU pharmaceutical legislation: Improving access to innovative drugs at the national level

Opioid settlement payouts to localities made public for first time

Overly restricting opioid use during surgery may be doing more harm than good

Study: Some breast cancer drugs may lessen the effect of weight loss medications

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

Study reveals sharp increase in hospital encounters for benzodiazepine-related toxicity among youth

Study examines the drivers of specialty drug diffusion

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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