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Research reveals racial and ethnic disparities in the benefits of newer type 2 diabetes drugs

New research analyzing the effects of two drugs used to treat type 2 diabetes indicates a consistent lack of cardiovascular and renal benefits in Black populations.

21 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Weill Cornell Medicine receives NIH grant to lead a national contraceptive research center

Weill Cornell Medicine has received a three-year, nearly $6 million grant to lead one of three national contraceptive research centers.

21 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Amoxicillin vs. amoxicillin-clavulanate: Which is more effective for acute sinusitis in children?

Brigham researchers found that patients prescribed amoxicillin-clavulanate had higher rates of gastrointestinal symptoms and yeast infections than those prescribed amoxicillin.

19 Sep 2023

Save billions or stick with Humira? Drug brokers steer Americans to the costly choice

Tennessee last year spent $48 million on a single drug, Humira — about $62,000 for each of the 775 patients who were covered by its employee health insurance program and receiving the treatment.

19 Sep 2023

Is Facebook's fight against vaccine misinformation failing?

Researchers found that Facebook's policies on removing COVID-19 vaccine misinformation are partially ineffective, as user engagement with anti-vaccine content did not decrease. The study suggests that the platform's system architecture allows users to bypass misinformation-curbing policies, making it challenging to combat the spread effectively.

18 Sep 2023

Is the new bivalent COVID-19 vaccine the booster we've been waiting for?

The bivalent COVID-19 vaccine developed by GSK and Sanofi shows promising results with a 64.7% overall effectiveness against symptomatic COVID-19, according to a phase 3 trial. The vaccine performs especially well as a booster, achieving 75.9% efficacy in non-naïve subjects.

17 Sep 2023

Experts provide guidance on opioid management in individuals with cancer-related pain

Clinicians treating cancer-related pain must consider whether and how to prescribe opioids to patients who use nonmedical stimulants such as cocaine and methamphetamines; however, no guidelines exist related to these common and challenging situations.

15 Sep 2023

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

A chemotherapy drug used to fight bone-marrow cancer also has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.

15 Sep 2023

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

The study finds that natural SARS-CoV-2 infection offers stronger immunity against the virus compared to mRNA vaccines. However, mRNA vaccines significantly reduce the infectiousness of individuals with COVID-19, playing a crucial role in limiting the virus's transmission.

14 Sep 2023

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

Researchers examined the effect of Bacillus Calmette-Guérin (BCG) vaccination on attenuating herpes labialis (cold sore) recurrences.

14 Sep 2023

CDC recommendations for pneumococcal vaccine in adults

Updated recommendations from the CDC on the use of pneumococcal vaccines in adults in the United States.

12 Sep 2023

New machine-learning algorithms can help optimize the next-generation of therapeutic antibodies

Antibody treatments may be able to activate the immune system to fight diseases like Parkinson’s, Alzheimer’s and colorectal cancer, but they are less effective when they bind with themselves and other molecules that aren’t markers of disease.

11 Sep 2023

Antidepressants may reduce negative memories, improve memory in depressed individuals

New research from Rice University finds that antidepressants may actually reduce negative memories in individuals suffering from depression while improving overall memory function.

11 Sep 2023

Vaccination amps up antibody response and cuts down COVID severity, UK study shows

UK study reveals COVID-19 vaccination effectively boosts anti-S antibody levels and reduces symptom severity post-infection, irrespective of the viral variant involved. High antibody levels are linked to quicker viral clearance, suggesting reduced transmission risk.

10 Sep 2023

Researchers use machine learning to predict drug approval chances before clinical trials

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. This is vital not only for advancing medicine but also for the overall health and well-being of humanity.

8 Sep 2023

Research review focuses on the use of psilocybin for treatment of depression

A growing body of evidence suggests that psychedelic drugs may be useful in treating various mental health conditions.

8 Sep 2023

Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

The Ohio State University Wexner Medical Center is one of the first nationwide to administer a targeted gene therapy for patients with a specific form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

8 Sep 2023

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Pharmaceutical News

Research reveals racial and ethnic disparities in the benefits of newer type 2 diabetes drugs

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Weill Cornell Medicine receives NIH grant to lead a national contraceptive research center

Transforming postpartum depression treatment with neurosteroids

Amoxicillin vs. amoxicillin-clavulanate: Which is more effective for acute sinusitis in children?

Save billions or stick with Humira? Drug brokers steer Americans to the costly choice

Is Facebook's fight against vaccine misinformation failing?

Is the new bivalent COVID-19 vaccine the booster we've been waiting for?

Experts provide guidance on opioid management in individuals with cancer-related pain

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

CDC recommendations for pneumococcal vaccine in adults

New machine-learning algorithms can help optimize the next-generation of therapeutic antibodies

Antidepressants may reduce negative memories, improve memory in depressed individuals

Vaccination amps up antibody response and cuts down COVID severity, UK study shows

Researchers use machine learning to predict drug approval chances before clinical trials

Research review focuses on the use of psilocybin for treatment of depression

Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

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