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Cracking the code on post-vaccine COVID protection

The study investigates the relationship between antibody levels and behavioral factors in 176 adults vaccinated with Pfizer's BNT162b2, finding that higher levels of specific antibodies correlate with greater protection against symptomatic COVID-19. It also suggests that current commercial assays may need reformatting for better risk prediction.

31 Aug 2023

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

The study finds that the fourth dose of the COVID-19 mRNA vaccine significantly boosts neutralizing antibody levels in the elderly, providing enhanced protection against new SARS-CoV-2 variants like Omicron. This supports the efficacy of booster shots for older populations in combating COVID-19.

31 Aug 2023

ADHD drug could serve as a cocaine-replacement therapy

Cocaine use continues to be a public health problem, yet despite concerted efforts, no drugs have been approved to resolve cocaine addiction. Research suggests that the attention-deficit/hyperactivity disorder drug methylphenidate (MPH; Ritalin) could serve as a cocaine-replacement therapy, but clinical results have been mixed.

30 Aug 2023

Study finds potential HIV cure using existing cancer drug

An existing blood cancer drug has shown promise in killing 'silent' HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.

30 Aug 2023

Artificial intelligence may influence whether you can get pain medication

Elizabeth Amirault had never heard of a Narx Score. But she said she learned last year the tool had been used to track her medication use.

30 Aug 2023

A move to cut drug prices has patients with rare diseases worried

For people with cystic fibrosis, like Sabrina Walker, Trikafta has been a life-changer.

30 Aug 2023

5 things to know about the new drug pricing negotiations

The Biden administration has picked the first 10 high-priced prescription drugs subject to federal price negotiations, taking a swipe at the powerful pharmaceutical industry.

30 Aug 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

Intellegens and CPI awarded £1.6m Innovate UK grant to advance manufacture of oligonucleotide therapeutics with machine learning

Intellegens, a company applying machine learning (ML) to accelerate innovation in R&D, today announced that it has secured a £1.6m grant from Innovate UK, part of UK Research and Innovation (UKRI), to apply ML in the emerging field of oligonucleotide therapies.

30 Aug 2023

Modern blood thinners linked to reduced risk of bleeding

Modern blood-thinning drugs (known as NOACs) reduce the risk of serious bleeding by up to 45 percent compared to the traditional drug Waran in the treatment of blood clots in the legs and lungs.

29 Aug 2023

Researchers elucidate the mode of action of cannabinoids in inflammation

A few days ago, the federal government took the controversial decision to make the acquisition and possession of small amounts of cannabis exempt from punishment.

29 Aug 2023

Analysis reveals limited evidence on use of cannabis products in children with cancer

A recent analysis of all relevant published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer.

29 Aug 2023

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

12 projects awarded a share of £5 million to reduce rates of fatal drug overdoses, as part of Vaccine Taskforce style approach to tackle health challenges.

29 Aug 2023

The past, present, and future of cancer drug development

A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, "Cancer drug development yesterday, today and tomorrow."

25 Aug 2023

New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

Acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are recommended as first-line treatments for managing short-term dental pain in children under age 12, according to a new clinical practice guideline developed by the American Dental Association Science & Research Institute (ADASRI), the University of Pittsburgh School of Dental Medicine and the Center for Integrative Global Oral Health at the University of Pennsylvania School of Dental Medicine.

25 Aug 2023

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Semaglutide could be a game-changer for patients with HFpEF and obesity

Semaglutide improves heart failure-related symptoms and physical function and results in greater weight loss compared with placebo in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

NHS England's Innovative Medicines Fund: A flawed approach to early access to new medicines

A new fund to fast-track patient access to potentially valuable new medicines may incentivize the pharmaceutical industry to develop high-priced drugs for rare diseases with weak evidence on clinical benefits.

25 Aug 2023

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

Researchers from the University of Minnesota Medical School and College of Pharmacy have found that high costs for hepatic encephalopathy treatment in patients with end-stage liver disease were associated with decreased treatment retention for patients.

25 Aug 2023

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Pharmaceutical News

Cracking the code on post-vaccine COVID protection

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

ADHD drug could serve as a cocaine-replacement therapy

Study finds potential HIV cure using existing cancer drug

Artificial intelligence may influence whether you can get pain medication

A move to cut drug prices has patients with rare diseases worried

5 things to know about the new drug pricing negotiations

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Intellegens and CPI awarded £1.6m Innovate UK grant to advance manufacture of oligonucleotide therapeutics with machine learning

Modern blood thinners linked to reduced risk of bleeding

Researchers elucidate the mode of action of cannabinoids in inflammation

Analysis reveals limited evidence on use of cannabis products in children with cancer

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

The past, present, and future of cancer drug development

New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Semaglutide could be a game-changer for patients with HFpEF and obesity

NHS England's Innovative Medicines Fund: A flawed approach to early access to new medicines

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

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