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Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.

3 May 2023

Long term treatment with beta blockers may not be warranted in patients who don’t have heart failure

The accepted clinical practice of using beta blockers over the long term to curb the risk of further heart attacks or death doesn't seem to be warranted in patients who don't have heart failure, suggests a large study published in the journal Heart.

3 May 2023

Monovalent mRNA COVID-19 vaccines provide durable protection against critical outcomes

Study reports on the effectiveness of monovalent mRNA vaccination in preventing COVID-19-associated invasive mechanical ventilation and death. In other words, the study looks at how well the mRNA vaccine works in preventing severe illness and death from COVID-19.

2 May 2023

UC San Francisco will be first hospital in California to offer pharmacogenetic testing

Beginning May 9, UC San Francisco will be the first hospital in California, and one of only a few nationwide, to offer pharmacogenetic testing.

2 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

The association between breastfeeding, drug exposure, and infant outcomes: more research is needed

Researchers explored the data linking breastfeeding, infant outcomes, and drug exposure.

28 Apr 2023

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Research discusses recent advances in computer-aided drug discovery, including the use of virtual screening and deep learning methods and their potential to revolutionize the drug discovery process by identifying diverse, potent, and drug-like ligands to protein targets.

28 Apr 2023

NVX-CoV2373 COVID vaccine safe and effective in preventing COVID-19 in adolescent

Research reports the results of a phase 3 clinical trial evaluating the safety, immunogenicity, and efficacy of the NVX-CoV2373 vaccine in adolescents aged 12 to 17 years. The study found that the vaccine was safe, immunogenic, and efficacious in preventing COVID-19, including the Delta variant, in adolescents.

27 Apr 2023

Molnupiravir treatment reduces risk of long COVID in high risk patients

Among high-risk individuals, molnupiravir treatment in the acute phase of infection could prevent long COVID.

27 Apr 2023

New test reveals FDA-approved antibiotics can effectively treat superbugs

A new test revealed that FDA-approved antibiotics -; available at your neighborhood pharmacy -; can effectively treat superbugs.

27 Apr 2023

Study assesses trends in buprenorphine initiation and retention in the United States

Treating opioid addiction should be much easier now than it was a few years ago, thanks to pandemic-era rule changes that aim to improve access to buprenorphine, a medicine proven to help in recovery.

25 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

Listen: Mifepristone remains available for now. What happens next?

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Pharmaceutical News

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Long term treatment with beta blockers may not be warranted in patients who don’t have heart failure

Monovalent mRNA COVID-19 vaccines provide durable protection against critical outcomes

UC San Francisco will be first hospital in California to offer pharmacogenetic testing

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

The association between breastfeeding, drug exposure, and infant outcomes: more research is needed

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

NVX-CoV2373 COVID vaccine safe and effective in preventing COVID-19 in adolescent

Molnupiravir treatment reduces risk of long COVID in high risk patients

New test reveals FDA-approved antibiotics can effectively treat superbugs

Study assesses trends in buprenorphine initiation and retention in the United States

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Listen: Mifepristone remains available for now. What happens next?

Poll shows the growing interest in “deprescribing” medications among older adults

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Pain, hope, and science collide as athletes turn to magic mushrooms

Deciphering immunological imprinting in the context of COVID-19

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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