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New method to assess the status of immune responses to specific antigens in detail

A new method to assess the status of immune responses to specific antigens in detail by analysis using the B cell receptor (BCR) repertoire has been developed by a research group, consisting of Assistant Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, Professor Hironobu Minami (Kobe University Graduate School of Medicine), Associate Professor Goh Ohji (Kobe University Hospital), and Researcher Takaji Matsutani (Repertoire Genesis Inc.).

18 Aug 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels.

17 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

KFF Health News' 'What the Health?': Abortion pill’s legal limbo continues

A divided three-judge federal appeals court panel has ruled that a lower court was wrong to try to reverse entirely the FDA's approval of the abortion drug mifepristone.

17 Aug 2023

Levonorgestrel-piroxicam co-treatment shows promise as more effective emergency contraception

Taking piroxicam, an anti-inflammatory medication commonly used for arthritis pain, at the same time as the levonorgestrel emergency contraceptive pill after unprotected sex prevents significantly more pregnancies compared to taking levonorgestrel alone, according to a randomised controlled trial published in The Lancet.

17 Aug 2023

Recreational drug use may worsen outcomes for cardiac intensive care patients

Recreational drug use may be a factor in a significant proportion of admissions to cardiac intensive care, with various substances detected in 1 in 10 such patients, suggest the findings of a multicentre French study published online in the journal Heart.

17 Aug 2023

Long-term use of proton pump inhibitors associated with increased risk of dementia

Researchers determine whether the current and cumulative use of prescription proton pump inhibitors increases the risk of incident dementia.

17 Aug 2023

Study: 93 million U.S. adults may benefit from semaglutide medication

Researchers from the University of California, Irvine have just published a study that projects 93 million U.S. adults that are overweight and obese may be suitable for the 2.4 mg dosage of semaglutide, a weight loss medication known under the brand name Wegovy.

16 Aug 2023

Many cancer drugs approved without clear evidence of benefit, study shows

New cancer drugs are being launched at a rapid pace, before their long-term effectiveness for patients can be evaluated.

15 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Scientists have developed a lymph node-targeted multi-epitope subunit vaccine that induces strong humoral and cellular immune responses against EBV in mice.

14 Aug 2023

$Study suggests Vitamin D prescription lowers hip fracture incidence$

Study suggests Vitamin D prescription lowers hip fracture incidence

Researchers examined the relationship between vitamin D supplementation and osteoporosis-related fracture incidence.

14 Aug 2023

New Alzheimer’s drug raises hopes — along with questions

The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer's and a precursor condition, mild cognitive impairment.

11 Aug 2023

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants.

11 Aug 2023

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Transplant recipients must take life-long immunosuppressive medications to prevent rejection, but these drugs can compromise the effectiveness of vaccines.

11 Aug 2023

Study explores the use of existing medicines to revolutionize cancer treatment

In a recent study published in the journal of Genes & Diseases, Research team led by Lu explores the potential for the use of FDA-approved hypertension and EMA-approved cough medicines to revolutionize cancer treatment.

10 Aug 2023

$Patients prescribed corticosteroids less likely to receive fracture preventive care$

Patients prescribed corticosteroids less likely to receive fracture preventive care

Prolonged use of corticosteroids, such as prednisolone, has been shown to cause osteoporosis and therefore increases the risk of breaking a bone.

10 Aug 2023

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

A personalized therapy selection algorithm for two diabetes type 2 (T2D) treatment drug classes.

10 Aug 2023

Dementia risk may increase with long-term use of acid reflux drugs

People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

9 Aug 2023

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Pharmaceutical News

New method to assess the status of immune responses to specific antigens in detail

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

KFF Health News' 'What the Health?': Abortion pill’s legal limbo continues

Levonorgestrel-piroxicam co-treatment shows promise as more effective emergency contraception

Recreational drug use may worsen outcomes for cardiac intensive care patients

Long-term use of proton pump inhibitors associated with increased risk of dementia

Study: 93 million U.S. adults may benefit from semaglutide medication

Many cancer drugs approved without clear evidence of benefit, study shows

Epigenetic manipulation may improve breast cancer treatment responses

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Study suggests Vitamin D prescription lowers hip fracture incidence

New Alzheimer’s drug raises hopes — along with questions

Illustrating the safety of a new drug treatment designed for spinal cord injury

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Study explores the use of existing medicines to revolutionize cancer treatment

Patients prescribed corticosteroids less likely to receive fracture preventive care

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

Dementia risk may increase with long-term use of acid reflux drugs

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