CRISPR News and Research

Latest CRISPR News and Research

Surprising discovery reveals new target for aggressive lung adenocarcinoma

Targeted therapies are currently available for about one-third of people with lung adenocarcinoma, the most common kind of lung cancer.

2 Dec 2020

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients' immune response to better attack malignant tumors.

2 Dec 2020

Telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Scientists use large-scale method to study genes associated with autism spectrum disorder

Scientists at Harvard University, the Broad Institute of MIT and Harvard, and MIT have developed a technology to investigate the function of many different genres in many different cell types at once, in a living organism.

1 Dec 2020

Research sheds new light on how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

25 Nov 2020

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

In a recent medRxiv* preprint paper, researchers from the University of Connecticut Health Center in the United States unveil their digital warm-start CRISPR (WS-CRISPR) method for stringent and sensitive quantitative detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples of patients with coronavirus disease (COVID-19).

24 Nov 2020

New link found between Alzheimer's dementia and Dlgap2 gene

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine.

23 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

Scientists develop a new vaccine approach for HIV

Unlike so many other deadly viruses, HIV still lacks a vaccine. The virus--which continues to infect millions around the world--has proven especially tricky to prevent with conventional antibodies, in part because it evolves so rapidly in the body.

20 Nov 2020

Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

The replacement of lost neurons is a holy grail for neuroscience. A new promising approach is the conversion of glial cells into new neurons. Improving the efficiency of this conversion or reprogramming after brain injury is an important step towards developing reliable regenerative medicine therapies.

17 Nov 2020

Researchers discover a mechanism that cells use to degrade microRNAs

UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.

12 Nov 2020

New method using light-activated liposomes is safer, more direct to deliver CRISPR gene therapy

Light-activated liposomes could help to deliver CRISPR gene therapy - and the method could prove safer and more direct than current methods.

12 Nov 2020

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver.

11 Nov 2020

Two paralogous androgen receptor genes control social dominance

Rank in social hierarchy is a condition not solely claimed by humans. In the animal kingdom, male peacocks exhibit brightly colored plumes to illustrate dominance, and underwater, male fish show pops of bright colors to do the same.

11 Nov 2020

How do low levels of oxygen damage the brain?

In this interview, Professor Paul Tesar and Kevin Allan speak to News-Medical about how low levels of oxygen damage the brain.

6 Nov 2020

Study shows iscan method could be effective for rapid COVID-19 testing

A simple COVID-19 test kit combines virus amplification with a CRISPR-Cas system for effective SARS-CoV-2 detection. The kit, called iSCAN, uses reagents that can be locally manufactured.

6 Nov 2020

New resource can help predict drug sensitivity and optimize therapeutic strategies

Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies.

6 Nov 2020

CRISPR News and Research

Latest CRISPR News and Research

Surprising discovery reveals new target for aggressive lung adenocarcinoma

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Telomere shortening helps prevent cancer in humans

Researchers successfully edit SIV virus from genomes of non-human primates

Scientists use large-scale method to study genes associated with autism spectrum disorder

Research sheds new light on how the CRISPR immune system evolved

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

New link found between Alzheimer's dementia and Dlgap2 gene

New findings could pave the way for more effective, safer and cheaper gene therapy

Scientists develop a new vaccine approach for HIV

Researchers uncover potential new target to fight inflammatory diseases

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

Researchers discover a mechanism that cells use to degrade microRNAs

New method using light-activated liposomes is safer, more direct to deliver CRISPR gene therapy

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Two paralogous androgen receptor genes control social dominance

How do low levels of oxygen damage the brain?

Study shows iscan method could be effective for rapid COVID-19 testing

New resource can help predict drug sensitivity and optimize therapeutic strategies

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