CRISPR News and Research

Latest CRISPR News and Research

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible are reviewed in the peer-reviewed journal Human Gene Therapy.

8 Oct 2020

SARS-CoV-2 infection analysis could help fight against COVID-19

Researchers in the United States has provided a detailed catalog of the interactions that occur between host cell proteins and RNA and the RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the course of infection.

7 Oct 2020

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

A large group of researchers from the United States reported developing an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from nasal swabs. Their state-of-the-art paper is currently available on the medRxiv* preprint server.

4 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

Compounds repurposed from malaria treatment can kill diarrheal pathogen

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

1 Oct 2020

Discovery of specific kinase as a novel drug target against SARS-CoV-2 and other coronaviruses

By using a modern genome-wide knockout approach to single out coronavirus host factors in human cells, researchers from Rega Institute in Belgium discovered a potential new target that might be exploited for developing drugs against the ongoing coronavirus disease (COVID-19) pandemic, but also future outbreaks of highly pathogenic coronaviruses

29 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

CRISPR screening identifies human host pathways that facilitate coronavirus infection

The human coronavirus family consists of 7 known pathogens, for which there are no approved vaccines or specific therapeutic options. Although the seasonal human coronaviruses - OC43, HKU1, 229E, and NL63 – only cause mild respiratory infections, three highly pathogenic coronaviruses that emerged in the last two decades revealed the pandemic potential of this family of viruses.

27 Sep 2020

Alzheimer’s disease-associated protective genetic variant enhances key functions of immune cells

A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer's disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer's disease.

25 Sep 2020

Scientists to use CRISPR gene-editing technology for Phase 1 vaccine trials in humans

Scientists are planning for Phase 1 human trials of a vaccine they developed by using CRISPR gene-editing technology to mutate the parasite that causes leishmaniasis, a skin disease common in tropical regions of the world and gaining ground in the United States

25 Sep 2020

Michael Arciero joins ERS Genomics as Vice-President of Intellectual Property and Commercial Development

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, today announced the appointment of Michael Arciero as Vice-President of Intellectual Property and Commercial Development.

23 Sep 2020

Common genetic variants may influence susceptibility to COVID-19

Researchers in the United States and Japan have conducted a study suggesting that a commonly occurring genetic variant influences susceptibility to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

23 Sep 2020

UConn researchers validate clinical feasibility of CRISPR-based platform for COVID-19 testing

In March, researchers in the Department of Biomedical Engineering-- a shared department in the schools of Dental Medicine, Medicine, and Engineering--began to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including HIV virus, the novel coronavirus (SARS-CoV-2).

19 Sep 2020

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property (IP) co-owned by Dr. Emmanuelle Charpentier, today announced it has signed an agreement with Applied StemCell, Inc., a leading provider of stem cell, animal model, antibody discovery services and reagents.

17 Sep 2020

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

Researchers from Peter the Great St.Petersburg Polytechnic University in collaboration with colleagues from the Pavlov University, ITMO University, and the University of Hamburg compared their developed carriers for delivery of genome editing (GE) tools with other available analogs.

16 Sep 2020

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Curi Bio today announced the Mantarray™ platform for human-relevant 3D engineered muscle tissue (EMT) analysis.

From Curi Bio 16 Sep 2020

3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

Pandemics caused by novel infectious agents like the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika, or Ebola virus seriously impact human health and lives while also overwhelming health care systems all over the world. Early detection and diagnosis allow isolation of the infected patients and contact tracing, which can mitigate the spread of the virus and save lives, especially when a significant number of the patients are asymptomatic.

14 Sep 2020

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's recipe to the cell's protein-making machinery.

14 Sep 2020

Veterinary college scientists pinpoint genes that drive ovarian cancer

High-grade serious ovarian carcinoma (HGSOC) is the fifth-leading cause of cancer-related deaths in women in the United States, yet little is known about the origins of this disease.

12 Sep 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

CRISPR News and Research

Latest CRISPR News and Research

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

SARS-CoV-2 infection analysis could help fight against COVID-19

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

Scientists map genetic networks that control the biology of regulatory T cells

Compounds repurposed from malaria treatment can kill diarrheal pathogen

Discovery of specific kinase as a novel drug target against SARS-CoV-2 and other coronaviruses

Risk factors for mortality among hospitalized patients with COVID-19

CRISPR screening identifies human host pathways that facilitate coronavirus infection

Alzheimer’s disease-associated protective genetic variant enhances key functions of immune cells

Scientists to use CRISPR gene-editing technology for Phase 1 vaccine trials in humans

Michael Arciero joins ERS Genomics as Vice-President of Intellectual Property and Commercial Development

Common genetic variants may influence susceptibility to COVID-19

UConn researchers validate clinical feasibility of CRISPR-based platform for COVID-19 testing

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Veterinary college scientists pinpoint genes that drive ovarian cancer

Scientists shed new light on gene regulatory pathways activated by stress hormone

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey