Pharmacology News and Research

Latest Pharmacology News and Research

Deletion of autism-linked gene diminishes myelin in mice

Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, new research finds.

21 Dec 2021

Scientists discover new autism biomarker in cerebrospinal fluid

Northwestern Medicine scientists have discovered a biomarker for one type of autism within patients' cerebrospinal fluid, according to a study published in the journal Neuron.

17 Dec 2021

Seda announces £4m investment in new state-of-the-art facilities

With huge growth in demand for its services, Seda has acquired a new property and is on track to double its annual turnover to at least £7m in the next two years.

From Seda Pharmaceutical Development Services 17 Dec 2021

Study determines minimally effective dose of clinical candidate gene therapy vector to treat hemophilia A

Researchers determined the minimally effective dose (MED) of a clinical candidate gene therapy vector for treating hemophilia A.

16 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Study details the effectiveness of face masks to reduce the spread of respiratory infections

Findings from a new study published today provide guidance for increasing the effectiveness of face masks to reduce the spread of respiratory infectious pathogens including SARS-CoV-2. T

16 Dec 2021

Combination treatment can effectively inhibit tumor growth

Researchers at the Paul Scherrer Institute PSI have tested various methods to check how effective they are in combatting certain types of cancer.

15 Dec 2021

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

An international research team co-led by scientists at Roswell Park Comprehensive Cancer Center and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified an important accelerator of treatment-resistant prostate cancer.

14 Dec 2021

Driving up immunity at tumor site may help enhance immunotherapy treatments

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

14 Dec 2021

Researchers uncover a key role for SIRT1 enzyme in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia. Despite advances in treatments, patients have an extremely poor prognosis, highlighting the need to explore the genetic components that lead to the formation of T-ALL, as well as the need to discover new targeted therapeutic approaches and treatment resistance.

14 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

UTSW study points to a new way to fight parasitic nematode diseases

Combining two agents to block a parasitic worm's life cycle boosted survival from a potentially deadly tropical disease to 85% in animal models, far better than either treatment alone, according to a proof-of-concept study led by UT Southwestern Medical Center pharmacologists.

11 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Study examines the extent of medication-related harm in pediatric intensive care units

In an observational study conducted across three pediatric intensive care units (PICUs) in England over a three-month period in 2019, one-sixth of patients experienced at least one adverse drug event, in which they were harmed by a medication.

8 Dec 2021

Study shows how senescent cells can be an underlying cause of kidney damage

A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in the linings of blood vessels, leads to cellular senescence, a process by which a cell ages and permanently stops dividing but does not die.

8 Dec 2021

Study analyzes the contribution of AI to cancer patient care and vaccine design

Artificial Intelligence/Machine Learning (AI/ML) is the development of computer systems that are able to perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home devices or digital voice assistants.

8 Dec 2021

Novel AI-based system models the progression of chronic diseases as patients age

Using artificial intelligence, a team of University at Buffalo researchers has developed a novel system that models the progression of chronic diseases as patients age.

7 Dec 2021

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Pharmacology News and Research

Latest Pharmacology News and Research

Deletion of autism-linked gene diminishes myelin in mice

Scientists discover new autism biomarker in cerebrospinal fluid

Seda announces £4m investment in new state-of-the-art facilities

Study determines minimally effective dose of clinical candidate gene therapy vector to treat hemophilia A

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Study details the effectiveness of face masks to reduce the spread of respiratory infections

Combination treatment can effectively inhibit tumor growth

Study provides new insights into molecular drivers of treatment resistance in prostate cancer

Driving up immunity at tumor site may help enhance immunotherapy treatments

Researchers uncover a key role for SIRT1 enzyme in T-cell acute lymphoblastic leukemia

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

UTSW study points to a new way to fight parasitic nematode diseases

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

Study examines the extent of medication-related harm in pediatric intensive care units

Study shows how senescent cells can be an underlying cause of kidney damage

Study analyzes the contribution of AI to cancer patient care and vaccine design

Novel AI-based system models the progression of chronic diseases as patients age

New protein variant underlies the ability of gastric cancers to resist chemotherapy

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Clinical drug research for the treatment of CNS and neurological disorders

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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