Pharmacology News and Research

Latest Pharmacology News and Research

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

More than 20 percent of adults in the United States live with chronic pain. For many affected individuals, long-term physical discomfort negatively impacts overall well-being, leading to reduced work output and increased anxiety and depression.

29 Sep 2021

Long-held theory of cancer-induced immune suppression requires revision, study says

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

29 Sep 2021

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease.

28 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

New research from Johns Hopkins Kimmel Cancer Center investigators shows why some drugs in clinical trials for treating a form of acute myeloid leukemia (AML) often fail and demonstrates a way to restore their effectiveness.

27 Sep 2021

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

Addictive psychostimulants, from nicotine in cigarettes to illicit drugs like methamphetamine and cocaine, affect different regions of the brain. The same is believed true during withdrawal; finding a common brain pathway has proved elusive.

27 Sep 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell.

24 Sep 2021

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder (NDD), according to a study published in the American Journal of Human Genetics.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Adhesive protein facilitates cluster formation in circulating tumor cells

Circulating tumor cells (CTCs) with stem cell features use the adhesive protein ICAM1 to facilitate formation of CTC clusters, which can travel from primary tumors to other organs in the body, according to a Northwestern Medicine study published in Nature Communications.

22 Sep 2021

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $11.7 million Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute.

22 Sep 2021

Hypertonic saline solution shown to inhibit replication of SARS-CoV-2

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the biochemical mechanism involved.

22 Sep 2021

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

17 Sep 2021

New imaging technique can change the landscape of prostate cancer detection and treatment

Prostate-specific membrane antigen, or PSMA, -targeted PET imaging for prostate cancer has been a breakthrough diagnosis tool in locating prostate cancer tumors for more precise treatment.

16 Sep 2021

New NIH-funded research to solve the male infertility and spermatogenesis puzzle

Male infertility is on the rise, with significant declines in sperm quantity and quality occurring across the human population worldwide in the past two decades.

16 Sep 2021

High adherence to Mediterranean diet improves cognitive functions and memory

People of advanced age who are overweight or obese with a higher level of adherence to the Mediterranean diet preserve their cognitive performance and even improve their abilities after three years, according to a new study.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

New technology offers a faster, easier and more efficient way to study gene function

Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.

15 Sep 2021

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

14 Sep 2021

Pharmacology News and Research

Latest Pharmacology News and Research

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

Long-held theory of cancer-induced immune suppression requires revision, study says

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

Cardiotoxic effects of common chemotherapy drug could be prevented

Scientists characterize new genetic variants that cause nonsyndromic neurodevelopmental disorder

Study provides novel insights into how KLF4 influences gene expression

Adhesive protein facilitates cluster formation in circulating tumor cells

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Hypertonic saline solution shown to inhibit replication of SARS-CoV-2

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

New imaging technique can change the landscape of prostate cancer detection and treatment

New NIH-funded research to solve the male infertility and spermatogenesis puzzle

High adherence to Mediterranean diet improves cognitive functions and memory

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

New technology offers a faster, easier and more efficient way to study gene function

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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