Pharmacology News and Research

Latest Pharmacology News and Research

New brain stimulation technique precisely controls motor activity without surgical device implantation

Neurological disorders such as Parkinson's disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation.

29 May 2021

New system can measure propofol concentration in patient's blood during surgery

Anesthesia may be an exact science, but it's not yet fully personalized. Anesthesiologists use a variety of methods to calculate the right dose for a given patient: clinical studies, medical databases and laboratory measurements, for example. However, every individual responds to anesthetics in a different way, and there's no way of knowing what that response will be until the anesthetic is administered.

29 May 2021

Study explains why it is difficult to withdraw from certain antidepressants

Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications.

28 May 2021

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body.

28 May 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021

Scientists propose new strategies to find drugs that neutralize critical enzymes

Scientists from the University of Bath explore racemases and propose strategies for finding drugs that target these important enzymes.

26 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Blocking ABCB10 protein in liver cells protects against high blood sugar, fatty liver disease

A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice.

20 May 2021

Scientists use anti-psychotics to treat flies displaying behavioral problems linked to schizophrenia-associated genes

Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.

20 May 2021

Potentially inappropriate prescribing linked to functional decline in older adults

Individuals are often prescribed increasing numbers of medications as they age, and while many of these prescriptions are justifiable, some may be inappropriate.

19 May 2021

Researchers use base editing to sustainably lower high LDL cholesterol levels

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence.

19 May 2021

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Parkinson's disease is the second most common neurodegenerative disease and affects more than 10 million people around the world.

19 May 2021

Sequentia collaborated with Nextbiomics to obtain a novel immunization model against COVID-19

Sequentia Biotech and NextBiomics announced the filing of a patent application for a bacterial vaccine against the COVID-19 syndrome.

From Sequentia Biotech 19 May 2021

Researchers report promising biotherapeutics for obesity and related medical complications

The research teams at the University of Hong Kong led by Professor Xuechen LI from the Research Division for Chemistry and Department of Chemistry, and Professor Yu WANG from the Department of Pharmacology and Pharmacy, reported a synthetic biotherapeutics with promising anti-tumor, insulin sensitising and hepatoprotective activities in the Journal of the American Chemical Society.

18 May 2021

What can ancient feces tell us about the evolution of the human gut microbiome?

Researchers at the Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center in Boston, Massachusetts, analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from dry caves in northern Mexico and Utah. They found that the ancient human gut microbiome is similar to those of modern-day people from non-industrialized populations.

14 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

$Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk$

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Hospitalized COVID-19 patients with impaired first-phase ejection fraction were nearly 5 times more likely to die compared to patients with healthier measures of this early, often undetected sign of heart failure, according to new research published today in Hypertension, an American Heart Association journal.

10 May 2021

Pharmacology News and Research

Latest Pharmacology News and Research

New brain stimulation technique precisely controls motor activity without surgical device implantation

New system can measure propofol concentration in patient's blood during surgery

Study explains why it is difficult to withdraw from certain antidepressants

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists propose new strategies to find drugs that neutralize critical enzymes

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

Blocking ABCB10 protein in liver cells protects against high blood sugar, fatty liver disease

Scientists use anti-psychotics to treat flies displaying behavioral problems linked to schizophrenia-associated genes

Potentially inappropriate prescribing linked to functional decline in older adults

Researchers use base editing to sustainably lower high LDL cholesterol levels

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Sequentia collaborated with Nextbiomics to obtain a novel immunization model against COVID-19

Researchers report promising biotherapeutics for obesity and related medical complications

What can ancient feces tell us about the evolution of the human gut microbiome?

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Novel CBD analog alleviates pain in mouse model of chemotherapy-induced peripheral neuropathy

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

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Pharmacology News and Research

Latest Pharmacology News and Research

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