Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Triad of cytokines associated with long COVID

A new study suggests a trio of cytokines — IL-1ß, IL-6, and TNF-α — are associated with long COVID symptoms.

18 Nov 2021

COVID-19 in open schools and preschools in Norway

A new study describes the cases and outbreaks of COVID-19 in schools and preschools in Norway to evaluate the strategy of keeping them open with control measures in place.

18 Nov 2021

Blood proteomic survey in undiagnosed population with COVID-19

In this study, scientists have profiled 276 circulating proteins that are associated with cardiovascular and metabolic functions.

18 Nov 2021

Real-world effectiveness and safety of COVID-19 vaccines

A new study published in Infectious Diseases of Poverty aimed to systematically evaluate the effectiveness and safety of the COVID-19 vaccines in the real world as well as establish a reliable evidence-based basis to determine the actual protective effect of the COVID-19 vaccines, especially considering the new waves of infection brought about by the variants.

18 Nov 2021

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

In a new study, researchers from French and American institutes analyzed at a molecular level the interaction between SARS-CoV-2 E protein and human TLR2.

17 Nov 2021

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential.

17 Nov 2021

Vaccines and boosters remain strong against current SARS-CoV-2 variants

In a recent study published in the Lancet Microbe journal, Australian researchers studied whether in-vitro neutralization titers could predict vaccine protection from SARS-CoV-2 variants.

17 Nov 2021

Long-term Pfizer vaccine-elicited SARS-CoV-2 antibody profile in breast milk

A new study indicates that the Pfizer vaccine induces antibodies in the breast milk against SARS-CoV-2.

17 Nov 2021

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

In the current study, researchers compare the IFITM sensitivities of major SARS-CoV-2 VOCs.

17 Nov 2021

SARS-CoV-2 reinfection associated with housing instability

Researchers examine the impact of demographic factors and antibody responses following SARS-CoV-2 reinfection.

17 Nov 2021

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

A recent study sed PBPK modeling to demonstrate the use of DEX PKs for the treatment of COVID-19 in patients with liver impairment.

17 Nov 2021

SARS-CoV-2-related smell loss lasts longer than previously thought

A recent study discusses the long-term prevalence of olfactory dysfunction in COVID-19 patients.

17 Nov 2021

Game animals as potential drivers of disease emergence

A study characterized the total virome of game animals from five mammalian orders using the total RNA sequencing technique.

17 Nov 2021

Effect of contact networks on SARS-CoV-2 transmission and control

A study demonstrated that the social contacts created in different activity settings affect interventions needed to control outbreaks.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

Efficacy of UVC light prototype devices for inactivating SARS-CoV-2

Researchers examined the efficacy of UVC light prototype devices to understand the duration and wavelength of UVC radiation needed for SARS-CoV-2 inactivation.

17 Nov 2021

Nationwide Swedish study strengthens evidence for a third booster COVID vaccine dose

A nationwide study from Sweden investigates the effectiveness of COVID-19 vaccination against the risk of symptomatic infection, hospitalization, and death up to 9 months post-vaccination. This study is published on the Preprints with The Lancet website while awaiting peer review.

17 Nov 2021

SARS-CoV-2 protease suppresses host immune response by cleaving NEMO

A recent study conducted by a team of US-based scientists has highlighted a novel function of 3C-like protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The protease has been found to cleave a human immune signaling protein called NF-kB Essential Modulator (NEMO) and disrupt the host immune response.

16 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021

Ensemble cryo-electron microscopy uncovers conformational states of the nsp13 helicase of SARS-CoV-2

With this background, the goal of a new study published on the bioRxiv* preprint server was to use cryo-electron microscopy to investigate the nsp13 helicase conformational states in order to gain insights of how nsp13 functions during viral transcription/replication.

16 Nov 2021