Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection.

16 Sep 2021

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

In order to address these issues, scientists from Xitific LTD and IDEAPharma in the UK proposed a novel approach to the framework of immune correlates, built upon the previous research. The framework formulated by the authors was developed for the mRNA-based vaccinations but could be applied to the other variations.

16 Sep 2021

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

According to new research by an international team of scientists, all SARS-CoV-2 variants, including variants of concern (VOC) Alpha, Beta, Gamma, and Delta, exhibit enhanced affinity toward recombinant human soluble ACE2.

16 Sep 2021

This 3D modeling reveals how SARS-CoV-2 attacks

Now, researchers at the Garvan Institute of Medical Research, Darlinghurst in Australia, CSIRO Data61, and the School of Biotechnology and Biomolecular Sciences (UNSW) demonstrated the most comprehensive analysis of the three-dimensional structure of SARS-CoV-2, providing a new insight into how the virus infects cells and replicates.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Study looks at exposure to different SARS-CoV-2 variants and immune response

Researchers compared the responses against several SARS-CoV-2 VoCs in sera from individuals exposed to variant infection, vaccination, or both.

15 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

The Indian second wave: SARS-CoV-2 infection-induced immunity could be ineffective in protecting population

Researchers decided to investigate how effective immunity gained from previous SARS-CoV-2 infection protects a wider community from disease.

15 Sep 2021

SARS-CoV-2 variants show substantial differences in spike structure

To investigate the impact of these mutations, researchers performed cryo-electron microscopy analysis on the variants spike proteins to determine any structural changes.

15 Sep 2021

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Scientists from the USA have demonstrated that immunity induced by mRNA-based COVID-19 vaccines in previously SARS-CoV-2-infected people has the highest robustness and durability with cross-reactivity against different viral variants.

15 Sep 2021

Vaccination of children before school reopening may control COVID-19 pandemic

A team has recently explored the impact of non-pharmaceutical control measures and vaccination on the COVID-19 pandemic during school reopening in England.

15 Sep 2021

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

A new study focused on in vitro antiviral activity in various cell models and in vivo therapeutic efficacy of oral GS-621763 in a mouse model of SARS-CoV-2 pathogenesis.

15 Sep 2021

MinoTour: a real-time monitoring platform to analyze SARS-CoV-2 nanopore sequencing

A study published on the bioRxiv* preprint sever focused on ONT sequencers that can rapidly provide data on the SARS-CoV-2 virus sequence.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

This state has come to be known as long-COVID, and in a paper recently uploaded to the preprint server medRxiv* by Simjanoska et al. (September 7th, 2021) the biochemical parameters of long-COVID patients with prior mild, moderate, or severe COVID-19 that resulted in hospitalization are tracked in detail, finding a characteristically dysregulated immune and inflammatory response in the most seriously ill.

15 Sep 2021

Quantification of salivary IgG and IgA against SARS-CoV-2

Salivary antibody levels are many fold lower than found in blood serum, Immunoglobulin G (IgG) in the saliva is mainly sourced from leakage from the gingival surface and Immunoglobulin A (IgA) from mucosal membranes.

15 Sep 2021

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

This 3D modeling reveals how SARS-CoV-2 attacks

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Analysis of the immune landscape in mild-to-moderate COVID-19

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

Study looks at exposure to different SARS-CoV-2 variants and immune response

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

The Indian second wave: SARS-CoV-2 infection-induced immunity could be ineffective in protecting population

SARS-CoV-2 variants show substantial differences in spike structure

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Vaccination of children before school reopening may control COVID-19 pandemic

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

MinoTour: a real-time monitoring platform to analyze SARS-CoV-2 nanopore sequencing

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

Quantification of salivary IgG and IgA against SARS-CoV-2

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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