Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Human neutralizing antibody pair blocks COVID-19-ACE2 binding

With the ongoing COVID-19 pandemic carving its deadly path across the world, and no end in sight in the immediate future, researchers are working furiously to bring out an effective therapeutic drug or vaccine that will stop the virus in its tracks.

10 May 2020

COVID-19 could accelerate activation of dormant tuberculosis (TB)

The ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has thrown much of the world into disarray, with over 4 million people reported infected and well over 282,000 deaths. A new study published on the preprint server bioRxiv in May 2020 suggests that the long-term impact of the virus could include activation of dormant bacterial infections like tuberculosis (TB).

10 May 2020

Neutralizing SARS-CoV-2 via S protein

A new study published on the preprint server bioRxiv* in May 2020 reports on a method to block severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by destroying its main spike protein, which is responsible for attachment to the host cell membrane.

10 May 2020

Low-molecular-weight drugs could help against COVID-19 says study

Chinese researchers have worked on using existing low molecular weight drugs to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

10 May 2020

Study demonstrates dynamic and broad-scale immune alterations in COVID-19 patient

A new case report released on the preprint server medRxiv* provides a detailed longitudinal analysis of the immune response associated with a fatal case of coronavirus disease (COVID-19). It highlights the need for addressing the source of hyper inflammation in the treatment approach.

10 May 2020

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

A new US study available on the preprint server medRxiv reveals certain genetic variations that are associated with infection susceptibility and diverse clinical presentation of coronavirus disease (COVID-19) – including asymptomatic cases and severe forms of the disease in younger patients.

10 May 2020

ACE inhibitors should not be discontinued over fears about COVID-19, say researchers

Researchers in Europe have found no evidence to support previous reports that the use of drugs that target the renin-angiotensin-aldosterone system (RAAS) increases susceptibility to coronavirus disease 2019 (COVID-19). The research is published in the European Heart Journal.

10 May 2020

Children are immune prepared for SARS-CoV-2

At least 30 new diseases have emerged in the last 20 years and now together threaten the health of hundreds of millions of people. For many of these diseases, there is no treatment, cure, or vaccine. While most of these diseases are dangerous to children, especially those younger than five years old, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seems to spare most of them.

8 May 2020

Antibodies from llamas may hold cure for novel coronavirus SARS-CoV-2

As scientists across the globe race to find an effective treatment for the novel coronavirus, a team of scientists believe that a four-year-old llama named Winter may hold the key to fight the coronavirus disease (COVID-19).

7 May 2020

New evidence suggests that schools should be kept closed to prevent COVID-19 spread

With most countries at a standstill, the circulating novel coronavirus has changed the way people live. Though some countries are starting to ease lockdown measures, with schools reopening, health experts worry that this may aggravate the situation. Two new studies provide evidence that children spread the coronavirus and transmit it, making them potential carriers of the infection.

7 May 2020

Predicting the dose for repurposing nitazoxanide in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports a model that could help evolve appropriate dosage protocols for future clinical trials of the repurposed drug nitazoxanide in COVID-19 prevention and treatment. The researchers say, “It was possible to achieve plasma and lung tizoxanide concentrations, using proven safe doses of nitazoxanide, that exceed the EC90 for SARS-CoV-2.”

7 May 2020

Study predicts the spread of COVID-19 in India

Dr. Shinjini Ghosh and colleagues from the Massachusetts Institute of Technology (MIT), United States, have come up with a predictive model that analyzes the spread of COVID-19 infection in India. Their study titled, "Predictive Model with Analysis of the Initial Spread of COVID-19 in India," was released prior to peer review on the preprint server Medrxiv.

7 May 2020

SARS-CoV-2 found in semen of COVID-19 patients

Since the novel coronavirus, now called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019, viral loads have been detected in body fluids, such as urine samples, saliva, stool samples, and in the gastrointestinal tract. Now, a new study reveals the SARS-CoV-2 virus in semen.

7 May 2020

U.S. needs to boost the number of beds for COVID-19 patients

A new study published in JAMA Network Open sheds light on the increased demand for intensive care and inpatient beds amid the coronavirus outbreak, based on two cities in China to determine the level of hospital capacity needed to respond to outbreaks of severe coronavirus disease 2019 in U.S. cities.

7 May 2020

Excluding children from COVID-19 clinical trials may limit their treatment options

A new viewpoint article from Harvard Medical School, published in the journal JAMA Pediatrics, discusses the hesitancy to include children in coronavirus disease 2019 (COVID-19) clinical trials, potentially diminishing their therapeutic options in the long run.

7 May 2020

Researchers show how bats carry the MERS coronavirus

A University of Saskatchewan (USask) research team has uncovered how bats can carry the Middle East respiratory syndrome (MERS) coronavirus without getting sick--research that could shed light on how coronaviruses make the jump to humans and other animals.

7 May 2020

The effect of weather on COVID-19 infection rate

Viral epidemics are nothing new in human history. Several viruses circulate freely every year among human beings, causing seasonal outbreaks of disease and death, such as the seasonal flu. A new study published on the preprint server medRxiv* reports that temperature plays a significant role in the growth of the ongoing COVID-19 pandemic.

6 May 2020

Air pollution associated with greater virulence of COVID-19

A new study published on the preprint server medRxiv* in April 2020 provides convincing evidence that air pollution contributes to greater severity of COVID-19. The researchers say, “This suggests the detrimental impact climate change will have on the trajectory of future respiratory epidemics.”

6 May 2020

SARS-CoV-2 in wastewater and rivers

A new study published on the preprint server medRxiv in May 2020 shows that while the virus causing COVID-19 may be present in wastewater and rivers, the biological agent is typically devoid of vitality and unable to cause active infection. This should provide some relief to public health authorities in their quest to contain the virus.

6 May 2020

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

The COVID-19 pandemic caused by the severe acute respiratory syndrome -coronavirus 2 (SARS-CoV-2) has spread to most of the world, causing millions of cases and hundreds of thousands of deaths. A new study published on the preprint server bioRxiv* shows that a protease inhibitor drug already approved by the Food and Drug Administration (FDA) could inhibit viral entry.

6 May 2020