T Cell News and Research

Latest T Cell News and Research

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens-;small fragments of randomly mutated proteins that are typically unique to a patient's cancer-;and destroy the tumors that express them.

15 Nov 2021

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

A recent study evaluates the immune responses elicited by COVID-19 vaccines in infliximab- or vedolizumab-treated IBD patients.

15 Nov 2021

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

A new study investigates serum from COVID-19 convalescents and uninfected individuals to determine the molecular mechanisms of host responses.

15 Nov 2021

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

The current study reveals that mice infected with mycobacterium tuberculosis are resistant to SARS-CoV-2 infection.

14 Nov 2021

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

Researchers study individuals recruited in the ‘Virus Watch’ community cohort who had received their second dose of either ChAdOx1 or BNT162b2 vaccine.

14 Nov 2021

Study assesses whether medicinal mushrooms and Chinese herbs can help treat COVID-19

A novel study is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.

12 Nov 2021

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

The Protective Immunity from T-cells to COVID-19 in Healthcare workers (PITCH) is a prospective, cohort, multi-center study enclosed within the SIREN study designed to assess the effectiveness of the BNT162b2 vaccine in healthcare workers.

12 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

A new study finds improved Fc cross-reactivity against certain SARS-CoV-2 variant of concern.

10 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Researchers describe the antibody-inducing effects of DNA-based synthetic vaccines INO-4800 and INO-4802 against SARS-CoV-2 in non-human primates.

3 Nov 2021

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T Cell News and Research

Latest T Cell News and Research

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers develop a highly efficient method to generate immune cells for cancer therapies

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

Study assesses whether medicinal mushrooms and Chinese herbs can help treat COVID-19

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Pfizer COVID-19 vaccine elicits durable specific memory T-cell response

Novel model-based framework evaluates immune mechanism of COVID-19 vaccine response

Adaptive immunity in patients infected with SARS-CoV-2 Δ382 Variant

Cross-reactive immunity against coronaviruses

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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