T Cell News and Research

Latest T Cell News and Research

Study uncovers how breast cancer cells use cholesterol to overcome stress-induced death mechanism

Chronically high cholesterol levels are known to be associated with increased risks of breast cancer and worse outcomes in most cancers, but the link has not been fully understood.

24 Aug 2021

Viral clearance accompanied by persistent footprints

Viruses do not always kill the cells they infect. Researchers at the University of Basel have discovered in experiments with mice that cells have the power to self-heal and eliminate viruses. However, these cells undergo long-term changes.

24 Aug 2021

Glycyrrhizic acid as a drug candidate for COVID-19

A new study presents the benefits of licorice, an age-old herbal remedy, to treat COVID-19 at all stages.

24 Aug 2021

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

A new study reports a case of pre-eclampsia complicated by the acute fatty liver of pregnancy (AFLP).

24 Aug 2021

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

Researchers at Albert Einstein College of Medicine and the City University of New York Graduate School of Public Health and Health Policy have been awarded a five-year, $14.5 million grant from the National Institutes of Health to continue leading and expand their research on HIV treatment and care in five Central African nations.

24 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

A new clinical trial to determine whether a third dose of vaccine will improve the immune response for people who have weakened immune systems is launching in the UK.

24 Aug 2021

Study identifies a key molecular mechanism driving COVID-19 mortality

An enzyme with an elusive role in severe inflammation may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target to reduce COVID-19 mortality.

24 Aug 2021

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

Carnivorous animals lack key genes needed to detect and respond to infection by pathogens, a study has found.

24 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Researchers develop brain organoids that show neural activity similar to living human brains

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids - 3D, brain-like structures grown from human stem cells - that show organized waves of activity similar to those found in living human brains.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

A new longitudinal study posted to the medRxiv* preprint server suggests vaccinated patients on chronic hemodialysis having waning immunity against severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern. The German researchers found a drop in neutralizing antibody levels and T cell activity four months after receiving their second Pfizer-BioNTech vaccine.

24 Aug 2021

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Though vaccination efforts are underway in most countries, there are still limited options for treating COVID-19. Now, researchers at Penn State designed a new COVID-19 therapy that uses a defective synthetic version of the SARS-CoV-2 virus to interfere with the actual virus's replication.

23 Aug 2021

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

By applying a systems biology approach, a recent bioRxiv* preprint research paper by scientists from the Icahn School of Medicine at Mount Sinai in New York unveils interactions between the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) and p38 mitogen-activated protein kinase (MAPK) pathway responsible for regulating the expression of crucial inflammatory mediators in human lung epithelial cells.

23 Aug 2021

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Viruses come in many forms, and Rice University bioengineer Isaac Hilton has long been fascinated by the kind that take control of cells without rewriting their genetic code.

23 Aug 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

Study discovers lagging chromosomes as one of the major causes of infertility

Why do women over 35 have more difficulty getting pregnant? After discovering one of the causes of age-related female infertility, researchers at the University of Montreal Hospital Research Centre suggest that it will be possible in the future to improve the quality of the eggs of older patients by intervening on the cell cycle level.

23 Aug 2021

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T Cell News and Research

Latest T Cell News and Research

Study uncovers how breast cancer cells use cholesterol to overcome stress-induced death mechanism

Viral clearance accompanied by persistent footprints

Glycyrrhizic acid as a drug candidate for COVID-19

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

New $14.5 million NIH grant to support research on HIV treatment and care in Central Africa

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

Study identifies a key molecular mechanism driving COVID-19 mortality

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Researchers develop brain organoids that show neural activity similar to living human brains

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Study suggests a novel therapeutic target to reverse lung fibrosis

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Study suggests algorithm may help optimize future COVID-19 vaccine design

Study discovers lagging chromosomes as one of the major causes of infertility

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

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Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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