Virus News and Research

Latest Virus News and Research

New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

The paper, put together by a team of scientists based in the United Kingdom and Italy, also underscored the need for healthcare policies to account for the very real possibility of inadequate protective personal equipment (PPE), staff and hospital capacity, aggravated by the increased number of pediatric infections.

15 Nov 2020

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

A new paper published in the journal Science of the Total Environment on November 10, 2020, discusses the reality of the virus’s wastewater transmission. Overall, the researchers found that wastewater transmission would have a disproportionate impact on countries with low development indices.

15 Nov 2020

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

To try and shed more light on SARS-CoV-2’s transmission, a research group based in Italy examined a COVID-19 isolation ward in a Milan hospital to evaluate the level of contamination present in the air and on surfaces with SARS-CoV-2 RNA (the virus’s genetic material).

15 Nov 2020

Promising new compounds to potentially treat novel coronaviruses identified

Researchers at the University of Maryland School of Medicine and School of Pharmacy have discovered new drug compounds to potentially treat the novel coronavirus that causes COVID-19.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Researchers in Sweden and China have presented a new methodology for predicting mutation “hotspot” sites within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Arthritis drug may improve COVID-19 survival among elderly patients

A type of arthritis drug may reduce the risk of dying for elderly patients with COVID-19.

15 Nov 2020

WHO approves first ever vaccine for emergency use to address polio

WHO today listed the nOPV2 vaccine (Bio Farma, Indonesia) for emergency use to address the rising cases of a vaccine-derived polio strain in a number of African and East Mediterranean countries.

15 Nov 2020

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19, from small samples of saliva, according to a study led by Bloomberg School researchers.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

A single-center study from Wuhan in China presents ultrasound imaging evidence supporting the notion that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause infection of the testis or epididymis – and put patients at risk for further complications. The paper can be found in the Journal of Ultrasound in Medicine.

15 Nov 2020

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

Researchers in Korea and the United States have identified novel genetic variants that demonstrate the active mutational progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Nov 2020

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

With the coronavirus disease 2019 (COVID-19) pandemic infecting over 52.7 million people around the world, and killing over 1.2 million, a large amount of research has tried to better understand immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

A research team from the Engelhardt Institute of Molecular Biology in Russia have shown that Nsp1 – a non-structured protein present in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen – stimulates translation termination in the stop codon recognition stage. Studying and developing drugs that compete with Nsp1 for binding with the termination complex could therefore be a potential strategy for fighting against coronavirus disease 2019 (COVID-19).

15 Nov 2020

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

A team of researchers at the Naval Medical Research Center, Silver Spring, USA, analyzed the risk of transmission of SARS-CoV-2 among marine recruits. Their study titled, “SARS-CoV-2 Transmission among Marine Recruits during Quarantine,” was published in the latest issue of the New England Journal of Medicine.

15 Nov 2020

Virus News and Research

Latest Virus News and Research

New data highlights safety concerns on rAAV vectors used in gene therapy

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

Promising new compounds to potentially treat novel coronaviruses identified

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Arthritis drug may improve COVID-19 survival among elderly patients

WHO approves first ever vaccine for emergency use to address polio

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

Harnessing proteomics could improve therapeutic approaches to COVID-19

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

A new way of characterising biomolecules eBook

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Virus News and Research

Latest Virus News and Research

A new way of characterising biomolecules eBook

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

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