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Roles of Selectins in the Immune System

Selectins are a family of carbohydrate-binding transmembrane molecules found on the surface of endothelial cells, leukocytes and platelets.

12 Apr 2018

Genomic Imprinting

Genomic imprinting refers to the selective expression of either the maternal or paternal allele, whilst the other remains inactive.

12 Apr 2018

Exosomes can be isolated from cells using typical methods for purifying cell fractions. The challenge in isolating vesicles is differentiating them from other types of membrane material in the cell culture supernatant.

12 Apr 2018

Applications of CAR T cells

CAR T cell therapy is a promising immunological treatment for cancer. It involves the engineering chimeric antigen receptors (CAR) to redirect T cells towards targeted cancer cells.

11 Apr 2018

Hallmarks of Cancer

There are six features, or hallmarks, of cancer that are used to organize our understanding of the stage of the disease.

11 Apr 2018

Microtubule Motor Proteins

Microtubule motor proteins move across the microtubule, transporting cellular cargo within the cell. They are responsible for mitosis, cellular transport and the movement of organelles.

10 Apr 2018

The Mechanism of DNA Damage by UV Radiation

Solar ultraviolet radiation (UV) exposure triggers DNA damage, a preliminary step in the process of carcinogenesis. Exposure to UV radiation alters the structure of DNA, affecting the physiological processes of all living systems ranging from bacteria to humans.

10 Apr 2018

Mitochondria Overview

Mitochondria are double membrane bound cytoplasmic organelles present in most eukaryotic cells. They are responsible for aerobic respiration, which they achieve through oxidative phosphorylation.

10 Apr 2018

What are Exosomes?

Exosomes are vesicles, or cellular components, that exist outside of a cell.

9 Apr 2018

Tunable Resistive Pulse Sensing Applications

Tunable resistive pulse sensing is used in single particle analysis to provide quantitative measurements that can be used in biology and nanotechnology.

9 Apr 2018

Immunoenzymatic Chromogen Staining

Immunoenzymatic staining of biological samples has grown to become a valuable tool for research and diagnostic purposes.

9 Apr 2018

Single Particle Analysis Techniques

For single particle analysis, electron microscopy is critical, processing techniques allow the structure of a single molecule or compound to be elucidated.

6 Apr 2018

What is Real-Time Quantitative PCR (qPCR)?

PCR is a commonly used method for amplifying DNA, which can then be used for gene cloning, sequencing, and for gene manipulation

5 Apr 2018

What is DNA Loop Extrusion?

DNA loop extrusion is a method used to analyze how DNA is compacted into the nucleus whilst bringing regulatory elements close to protein coding genes.

4 Apr 2018