Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Antibody Sequencing

Antibody protein sequencing is simply defining the sequence of amino acids of an unknown antibody. The use of mass spectrometry in de novo sequencing of antibody protein has made it possible to perform this without having the cell lines available or knowing the DNA sequence beforehand.

From Rapid Novor Inc 18 Jun 2018

Measuring Double-Stranded DNA with Fluorescent Dyes: Qubit on BMG Labtech Instruments

Measuring double-stranded DNA with fluorescent dyes, is described in this article as part of applications like next generation sequencing (NGS).

From BMG LABTECH GmbH 14 Jun 2018

Testing Living Cells to Measure Cell Compression

Living cells frequently show altered mechanical properties following infection and disease. It is possible to detect whether and how any given cell is affected using quantitative tests of the mechanical stiffness of the cell membrane on a nanoscale.

From Bruker Nano Surfaces and Metrology 14 Jun 2018

Inhibition of Mitochondrial Permeability Transition Pore Evaluated by Calcium Retention Capacity Assay

A rise in inner mitochondrial membrane permeability, through consistent mitochondrial permeability transition pore opening results in mitochondrial dysfunction

From BMG LABTECH GmbH 14 Jun 2018

Ensuring the Quality of Manufactured Heparin

Heparin is a naturally occurring anticoagulant released from mast cells. It binds reversibly with anti-thrombin, which leads to increased inactivation of coagulation enzymes, whereby preventing blood clot formation. It is a mixture of sulphated glycosaminoglycan polymers.

From Bruker BioSpin - NMR, EPR and Imaging 12 Jun 2018

Determining the Secondary Structures of Proteins

Fourier-transform infrared spectroscopy, also known as FTIR spectroscopy, has made its mark as a very versatile technique of analysis.

From Thermo Fisher Scientific - Vibrational Spectroscopy 12 Jun 2018

Combating the Opioid Epidemic with FT-Raman Spectroscopy

Fentanyl manufactured by illicit means is driving an overdose epidemic, according to data released by the Centers for Disease Control and Prevention (CDC).

From Thermo Fisher Scientific - Vibrational Spectroscopy 12 Jun 2018

Chemical Imaging for Pharmaceutical Process Analytical Technology

Mid-infrared (mid-IR) spectroscopy is an established imaging method for characterizing a broad range of materials.

From Daylight Solutions Inc 8 Jun 2018

Metabolomics in the Study of Soil Toxicity

Earthworms make up 60% of soil biomass and play a critical role in the turnover of soil organic matter and nutrients in both natural and agricultural settings. Earthworms live surrounded by soil and ingest soil, complete with any contaminants it may contain.

From Bruker BioSpin - NMR, EPR and Imaging 5 Jun 2018

Structural Analysis of Plant Pigments

Plant pigments are the beautiful array of colors seen in the plant world is created by the pigments they produce.

From Bruker BioSpin - NMR, EPR and Imaging 29 May 2018

Labelling Pancreatic Islets for Transplantation Using NMR

Organ transplantation has transformed the lives of many patients with kidney disease, lung disease and heart disease. However, transplantation still requires immunosuppressive medications to prevent attack from the immune system of the recipient.

From Bruker BioSpin - NMR, EPR and Imaging 22 May 2018

Characterising Protein - DNA Complexes

Proteins and nucleic acids often bind in stoichiometric ratios above 1:1, resulting in phenomena such as cooperativity or allosteric hindrance.

From Waters | Wyatt Technology 17 May 2018

Analysis of Expired VOCs

The Breath Analysis of Expired VOCs during Exercise markers in human breath for the determination of physiological events such as lactate threshold and oxidative stress remains a challenge for conventional ‘off-line’ gas analysis equipment, such as GCMS.

From Hiden Analytical 16 May 2018