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Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

In the early days of the pandemic, with commercial COVID tests in short supply, Rockefeller's Robert B. Darnell developed an in-house assay to identify positive cases within the Rockefeller community.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Quantification of salivary IgG and IgA against SARS-CoV-2

Salivary antibody levels are many fold lower than found in blood serum, Immunoglobulin G (IgG) in the saliva is mainly sourced from leakage from the gingival surface and Immunoglobulin A (IgA) from mucosal membranes.

15 Sep 2021

Prior symptomatic COVID-19 enhances mRNA vaccine response

A new paper describes the antibody responses in people who have already been infected with SARS-CoV-2 and are vaccinated as compared to the naïve.

14 Sep 2021

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in their blood serum at the start of anti-estrogen treatment live longer and go longer without their disease progressing than patients with high levels.

14 Sep 2021

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Dynamics of healthcare-associated SARS-CoV-2 infections revealed with whole genome sequencing

In a recent paper, the researchers study the dynamics of SARS-CoV-2 infections on a geriatric hospital ward by whole genome sequencing.

13 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

This study revealed that the CV3-13 antibody can mediate Fc effector functions against S protein-expressing cells.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

A group of researchers analyzed the B cell response to SARS-CoV-2 in unexposed individuals.

10 Sep 2021

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

Researchers in Japan have warned that the Mu (B.1.621) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – appears to be highly resistant to neutralization by sera from convalescent or vaccinated individuals.

8 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

A new study reignites the debate regarding the therapeutic utility of convalescent plasma in treating others with the COVID-19.

7 Sep 2021

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

7 Sep 2021

Assay News and Research

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Aptamers for Targeting SARS-CoV-2 Proteins

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

Quantification of salivary IgG and IgA against SARS-CoV-2

Prior symptomatic COVID-19 enhances mRNA vaccine response

Blood serum test can identify which breast cancer patients have slow-growing disease

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

Dynamics of healthcare-associated SARS-CoV-2 infections revealed with whole genome sequencing

New SARS-CoV-2 mechanism of host gene suppression

Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

Novel assay helps identify factors that can convert normal cells into liver cancer cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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